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Phase 1 drug-drug interaction study to assess the effect of CYP3A4 inhibition and pan-CYP induction on the pharmacokinetics and safety of fosmanogepix in healthy participants
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Published in Antimicrobial agents and chemotherapy (17.05.2024)
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Pharmacokinetics and pharmacodynamics of the endothelin-receptor antagonist bosentan in healthy human subjects
Weber, C, Schmitt, R, Birnboeck, H, Hopfgartner, G, van Marle, S P, Peeters, P A, Jonkman, J H, Jones, C R
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Published in Clinical pharmacology and therapeutics (01.08.1996)
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Pharmacokinetics, safety, and tolerability of fosmanogepix IV to oral switch and multiple IV doses in healthy participants
Hodges, Michael R, Hazel, Susan, Kramer, William G, van Hoogdalem, Ewoud-Jan, van Marle, Sjoerd, Tawadrous, Margaret, Jakate, Abhijeet
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Published in Antimicrobial agents and chemotherapy (02.05.2024)
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Absorption, metabolism and excretion of darexaban (YM150), a new direct factor Xa inhibitor in humans
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Published in Xenobiotica (01.06.2013)
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Sugammadex is cleared rapidly and primarily unchanged via renal excretion
Peeters, Pierre, Passier, Paul, Smeets, Jean, Zwiers, Alex, de Zwart, Marcel, van de Wetering-Krebbers, Saskia, van Iersel, Marlou, van Marle, Sjoerd, van den Dobbelsteen, Diels
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Published in Biopharmaceutics & drug disposition (01.04.2011)
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Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a randomised study
Cahn, Anthony, Hodgson, Simon, Wilson, Robert, Robertson, Jonathan, Watson, Joanna, Beerahee, Misba, Hughes, Steve C, Young, Graeme, Graves, Rebecca, Hall, David, van Marle, Sjoerd, Solari, Roberto
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Published in BMC pharmacology & toxicology (28.02.2013)
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