Generating Virtual Patients by Multivariate and Discrete Re-Sampling Techniques
Teutonico, D., Musuamba, F., Maas, H. J., Facius, A., Yang, S., Danhof, M., Della Pasqua, O.
Published in Pharmaceutical research (01.10.2015)
Published in Pharmaceutical research (01.10.2015)
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Journal Article
Pharmacokinetic–pharmacodynamic modelling of drug‐induced QTc interval prolongation in man: prediction from in vitro human ether‐à‐go‐go‐related gene binding and functional inhibition assays and conscious dog studies
Dubois, V F S, Casarotto, E, Danhof, M, Della Pasqua, O
Published in British journal of pharmacology (01.10.2016)
Published in British journal of pharmacology (01.10.2016)
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Journal Article
Drug effects on the CVS in conscious rats: separating cardiac output into heart rate and stroke volume using PKPD modelling
Snelder, N, Ploeger, B A, Luttringer, O, Rigel, D F, Fu, F, Beil, M, Stanski, D R, Danhof, M
Published in British journal of pharmacology (01.11.2014)
Published in British journal of pharmacology (01.11.2014)
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Journal Article
Population pharmacokinetic modelling of total and unbound cefazolin plasma concentrations as a guide for dosing in preterm and term neonates
De Cock, R F W, Smits, A, Allegaert, K, de Hoon, J, Saegeman, V, Danhof, M, Knibbe, C A J
Published in Journal of antimicrobial chemotherapy (01.05.2014)
Published in Journal of antimicrobial chemotherapy (01.05.2014)
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Journal Article
Mechanism-based pharmacokinetic-pharmacodynamic modeling-a new classification of biomarkers
Danhof, Meindert, Alvan, Gunnar, Dahl, Svein G, Kuhlmann, Jochen, Paintaud, Gilles
Published in Pharmaceutical research (01.09.2005)
Published in Pharmaceutical research (01.09.2005)
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Journal Article
A model-based approach to dose selection in early pediatric development
Cella, M, Gorter de Vries, F, Burger, D, Danhof, M, Della Pasqua, O
Published in Clinical pharmacology and therapeutics (01.03.2010)
Published in Clinical pharmacology and therapeutics (01.03.2010)
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Journal Article
Inter‐study variability of preclinical in vivo safety studies and translational exposure–QTc relationships – a PKPD meta‐analysis
Gotta, V, Cools, F, Ammel, K, Gallacher, D J, Visser, S A G, Sannajust, F, Morissette, P, Danhof, M, Graaf, P H
Published in British journal of pharmacology (01.09.2015)
Published in British journal of pharmacology (01.09.2015)
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Journal Article
PKPD modelling of the interrelationship between mean arterial BP, cardiac output and total peripheral resistance in conscious rats
Snelder, N, Ploeger, B A, Luttringer, O, Rigel, D F, Webb, R L, Feldman, D, Fu, F, Beil, M, Jin, L, Stanski, D R, Danhof, M
Published in British journal of pharmacology (01.08.2013)
Published in British journal of pharmacology (01.08.2013)
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Journal Article
Understanding the Behavior of Systems Pharmacology Models Using Mathematical Analysis of Differential Equations: Prolactin Modeling as a Case Study
Bakshi, S, de Lange, EC, van der Graaf, PH, Danhof, M, Peletier, LA
Published in CPT: pharmacometrics and systems pharmacology (01.07.2016)
Published in CPT: pharmacometrics and systems pharmacology (01.07.2016)
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Journal Article
Pharmacokinetic-Pharmacodynamic Modeling of the Antinociceptive Effect of Buprenorphine and Fentanyl in Rats: Role of Receptor Equilibration Kinetics
Yassen, Ashraf, Olofsen, Erik, Dahan, Albert, Danhof, Meindert
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
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Journal Article
Disease severity is a major determinant for the pharmacodynamics of propofol in critically ill patients
Peeters, M Y M, Bras, L J, DeJongh, J, Wesselink, R M J, Aarts, L P H J, Danhof, M, Knibbe, C A J
Published in Clinical pharmacology and therapeutics (01.03.2008)
Published in Clinical pharmacology and therapeutics (01.03.2008)
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