Design, Synthesis, and Biological Activity of Potent and Selective Inhibitors of Blood Coagulation Factor Xa
Willardsen, J. Adam, Dudley, Danette A, Cody, Wayne L, Chi, Liguo, McClanahan, Thomas B, Mertz, Thomas E, Potoczak, Ronald E, Narasimhan, Lakshmi S, Holland, Debra R, Rapundalo, Stephen T, Edmunds, Jeremy J
Published in Journal of medicinal chemistry (29.07.2004)
Published in Journal of medicinal chemistry (29.07.2004)
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Rational Design, Synthesis, and Biological Activity of Benzoxazinones as Novel Factor Xa Inhibitors
Dudley, Danette A, Bunker, Amy M, Chi, Liguo, Cody, Wayne L, Holland, Debra R, Ignasiak, Diane P, Janiczek-Dolphin, Nancy, McClanahan, Thomas B, Mertz, Thomas E, Narasimhan, Lakshmi S, Rapundalo, Stephen T, Trautschold, Julia A, Van Huis, Chad A, Edmunds, Jeremy J
Published in Journal of medicinal chemistry (02.11.2000)
Published in Journal of medicinal chemistry (02.11.2000)
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Ranolazine reduces remodeling of the right ventricle and provoked arrhythmias in rats with pulmonary hypertension
Liles, John T, Hoyer, Kirsten, Oliver, Jason, Chi, Liguo, Dhalla, Arvinder K, Belardinelli, Luiz
Published in The Journal of pharmacology and experimental therapeutics (01.06.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2015)
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Profibrillatory actions of pinacidil in a conscious canine model of sudden coronary death
Chi, L, Uprichard, A C, Lucchesi, B R
Published in Journal of cardiovascular pharmacology (01.03.1990)
Published in Journal of cardiovascular pharmacology (01.03.1990)
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Long-term stability, reproducibility, and statistical sensitivity of a telemetry-instrumented dog model: A 27-month longitudinal assessment
Fryer, Ryan M., Ng, Khing Jow, Chi, Liguo, Jin, Xidong, Reinhart, Glenn A.
Published in Journal of pharmacological and toxicological methods (01.07.2015)
Published in Journal of pharmacological and toxicological methods (01.07.2015)
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Antifibrillatory and profibrillatory actions of selected class I antiarrhythmic agents
Fagbemi, S O, Chi, L, Lucchesi, B R
Published in Journal of cardiovascular pharmacology (01.05.1993)
Published in Journal of cardiovascular pharmacology (01.05.1993)
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Antifibrillatory effects of clofilium in the rabbit isolated heart
Friedrichs, Gregory S., Chi, Liguo, Green, Alysia L., Lucchesi, Benedict R.
Published in British journal of pharmacology (01.09.1994)
Published in British journal of pharmacology (01.09.1994)
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Strategic integration of in vivo cardiovascular models during lead optimization: predictive value of 4 models independent of species, route of administration, and influence of anesthesia
Fryer, Ryan M, Harrison, Paul C, Muthukumarana, Akalushi, Nodop Mazurek, Suzanne G, Ng, Khing Jow, Chen, Rong Rhonda, Harrington, Kyle E, Dinallo, Roger M, Chi, Liguo, Reinhart, Glenn A
Published in Journal of cardiovascular pharmacology (01.04.2012)
Published in Journal of cardiovascular pharmacology (01.04.2012)
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The Discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide (PD 0348292), an Orally Efficacious Factor Xa Inhibitor
Kohrt, Jeffrey T., Bigge, Christopher F., Bryant, John W., Casimiro-Garcia, Agustin, Chi, Liguo, Cody, Wayne L., Dahring, Tawny, Dudley, Danette A., Filipski, Kevin J., Haarer, Staci, Heemstra, Ron, Janiczek, Nancy, Narasimhan, Lakshmi, McClanahan, Thomas, Peterson, J. Thomas, Sahasrabudhe, Vaisheli, Schaum, Robert, Van Huis, Chad A., Welch, Kathleen M., Zhang, Erli, Leadley, Robert J., Edmunds, Jeremy J.
Published in Chemical biology & drug design (01.08.2007)
Published in Chemical biology & drug design (01.08.2007)
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Celiprolol does not protect against ventricular tachycardia or sudden death in the conscious canine: a comparison with pindolol in assessing the role of intrinsic sympathomimetic activity
UPRICHARD, A. C. G, LIGUO CHI, KITZEN, J. M, LYNCH, J. J, FRYE, J. W, LUCCHESI, B. R
Published in The Journal of pharmacology and experimental therapeutics (01.11.1989)
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Published in The Journal of pharmacology and experimental therapeutics (01.11.1989)
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Alinidine reduces the incidence of ischemic ventricular fibrillation in a conscious canine model, a protective effect antagonized by overdrive atrial pacing
Uprichard, A C, Chi, L G, Lynch, J J, Driscoll, E M, Frye, J W, Lucchesi, B R
Published in Journal of cardiovascular pharmacology (01.09.1989)
Published in Journal of cardiovascular pharmacology (01.09.1989)
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In vitro and in vivo antithrombotic activity of PD-198961, a novel synthetic factor Xa inhibitor
Chi, Liguo, Peng, Yun-Wen, Gibson, Glenn, Hicks, Gary, Mertz, Thomas E, Rapundalo, Stephen, Janiczek, Nancy, Edmunds, Jeremy J, Leadley, Robert
Published in Journal of cardiovascular pharmacology (01.10.2004)
Published in Journal of cardiovascular pharmacology (01.10.2004)
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Effects of tedisamil (KC‐8857) on cardiac electrophysiology and ventricular fibrillation in the rabbit isolated heart
Chi, Liguo, Park, James L., Friedrichs, Gregory S., Banglawala, Yasmin A., Perez, Maria A., Tanhehco, Elaine J., Lucchesi, Benedict R.
Published in British journal of pharmacology (01.03.1996)
Published in British journal of pharmacology (01.03.1996)
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Antifibrillatory effects of ibutilide in the rabbit isolated heart: mediation via ATP-dependent potassium channels
Friedrichs, G S, Chi, L, Black, S C, Manley, P J, Oh, J Y, Lucchesi, B R
Published in The Journal of pharmacology and experimental therapeutics (01.09.1993)
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Published in The Journal of pharmacology and experimental therapeutics (01.09.1993)
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