Effect of alcohol coadministration on the pharmacodynamics, pharmacokinetics, and safety of lemborexant: A randomized, placebo-controlled crossover study
Landry, Ishani, Hall, Nancy, Aluri, Jagadeesh, Filippov, Gleb, Setnik, Beatrice, Dayal, Satish, Reyderman, Larisa, Moline, Margaret
Published in Journal of psychopharmacology (Oxford) (01.06.2022)
Published in Journal of psychopharmacology (Oxford) (01.06.2022)
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Journal Article
Pharmacokinetics, Pharmacodynamics, and Safety of the Dual Orexin Receptor Antagonist Lemborexant: Findings From Single‐Dose and Multiple‐Ascending‐Dose Phase 1 Studies in Healthy Adults
Landry, Ishani, Nakai, Kenya, Ferry, Jim, Aluri, Jagadeesh, Hall, Nancy, Lalovic, Bojan, Moline, Margaret L.
Published in Clinical pharmacology in drug development (01.02.2021)
Published in Clinical pharmacology in drug development (01.02.2021)
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Journal Article
Effect of Rifampicin on the Pharmacokinetics of Lenvatinib in Healthy Adults
Shumaker, Robert C., Aluri, Jagadeesh, Fan, Jean, Martinez, Gresel, Thompson, Gary A., Ren, Min
Published in Clinical drug investigation (01.09.2014)
Published in Clinical drug investigation (01.09.2014)
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Journal Article
Concentration-Response Modeling of ECG Data From Early-Phase Clinical Studies as an Alternative Clinical and Regulatory Approach to Assessing QT Risk - Experience From the Development Program of Lemborexant
Murphy, Patricia J, Yasuda, Sanae, Nakai, Kenya, Yoshinaga, Takashi, Hall, Nancy, Zhou, Meijian, Aluri, Jagadeesh, Rege, Bhaskar, Moline, Margaret, Ferry, Jim, Darpo, Borje
Published in Journal of clinical pharmacology (01.01.2017)
Published in Journal of clinical pharmacology (01.01.2017)
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Journal Article
Population pharmacokinetic‐pharmacodynamic modeling of serum biomarkers as predictors of tumor dynamics following lenvatinib treatment in patients with radioiodine‐refractory differentiated thyroid cancer (RR‐DTC)
Majid, Oneeb, Hayato, Seiichi, Sreerama Reddy, Sree Harsha, Lalovic, Bojan, Hihara, Taro, Hoshi, Taisuke, Funahashi, Yasuhiro, Aluri, Jagadeesh, Takenaka, Osamu, Yasuda, Sanae, Hussein, Ziad
Published in CPT: pharmacometrics and systems pharmacology (01.06.2024)
Published in CPT: pharmacometrics and systems pharmacology (01.06.2024)
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Journal Article
Evaluation of the effects of formulation and food on the pharmacokinetics of lenvatinib (E7080) in healthy volunteers
Shumaker, Robert, Aluri, Jagadeesh, Fan, Jean, Martinez, Gresel, Ren, Min, Chen, Kun
Published in International journal of clinical pharmacology and therapeutics (01.04.2014)
Published in International journal of clinical pharmacology and therapeutics (01.04.2014)
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Journal Article
Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant
Landry, Ishani, Aluri, Jagadeesh, Hall, Nancy, Filippov, Gleb, Dayal, Satish, Moline, Margaret, Reyderman, Larisa
Published in Pharmacology research & perspectives (01.04.2021)
Published in Pharmacology research & perspectives (01.04.2021)
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Journal Article
Bioavailability of Three Rufinamide Oral Suspensions Compared With the Marketed 400-mg Tablet Formulation: Results From a Randomized-Sequence, Open-Label, Four-Period, Four-Sequence Crossover Study in Healthy Subjects
Critchley, David John, PhD, Aluri, Jagadeesh, MS, Boyd, Peter, MSc, Whayman, Matthew, MSc, Narurkar, Milind, PhD, Delargy, Hugh, PhD, Bibbiani, Francesco, MD
Published in Clinical therapeutics (2011)
Published in Clinical therapeutics (2011)
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Journal Article
Population Pharmacokinetics and Exposure‐Response Analyses for the Most Frequent Adverse Events Following Treatment With Lemborexant, an Orexin Receptor Antagonist, in Subjects With Insomnia Disorder
Lalovic, Bojan, Majid, Oneeb, Aluri, Jagadeesh, Landry, Ishani, Moline, Margaret, Hussein, Ziad
Published in Journal of clinical pharmacology (01.12.2020)
Published in Journal of clinical pharmacology (01.12.2020)
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Journal Article
Disposition and Metabolism of [ 14 C]Lemborexant in Healthy Human Subjects and Characterization of Its Circulating Metabolites
Ueno, Takashi, Ishida, Tomomi, Aluri, Jagadeesh, Suzuki, Michiyuki, Beuckmann, Carsten T, Kameyama, Takaaki, Asakura, Shoji, Kusano, Kazutomi
Published in Drug metabolism and disposition (01.01.2021)
Published in Drug metabolism and disposition (01.01.2021)
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Journal Article
Pharmacokinetics, Pharmacodynamics, Pharmacogenomics, Safety, and Tolerability of Avatrombopag in Healthy Japanese and White Subjects
Nomoto, Maiko, Pastino, Gina, Rege, Bhaskar, Aluri, Jagadeesh, Ferry, Jim, Han, David
Published in Clinical pharmacology in drug development (01.02.2018)
Published in Clinical pharmacology in drug development (01.02.2018)
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Journal Article
Pharmacokinetic/pharmacodynamic drug–drug interactions of avatrombopag when coadministered with dual or selective CYP2C9 and CYP3A interacting drugs
Nomoto, Maiko, Zamora, Cynthia A., Schuck, Edgar, Boyd, Peter, Chang, Min‐Kun, Aluri, Jagadeesh, Siu, Y. Amy, Lai, W. George, Yasuda, Sanae, Ferry, Jim, Rege, Bhaskar
Published in British journal of clinical pharmacology (01.05.2018)
Published in British journal of clinical pharmacology (01.05.2018)
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Journal Article
An Open-Label Phase 1 Study to Determine the Effect of Lenvatinib on the Pharmacokinetics of Midazolam, a CYP3A4 Substrate, in Patients with Advanced Solid Tumors
Shumaker, Robert, Ren, Min, Aluri, Jagadeesh, Dutcus, Corina E., Rance, Christian, He, Cixin
Published in European journal of drug metabolism and pharmacokinetics (01.06.2020)
Published in European journal of drug metabolism and pharmacokinetics (01.06.2020)
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Journal Article
Intravenous Perampanel as an Interchangeable Alternative to Oral Perampanel: A Randomized, Crossover, Phase I Pharmacokinetic and Safety Study
Hussein, Ziad, Majid, Oneeb, Boyd, Peter, Aluri, Jagadeesh, Ngo, Leock Y, Reyderman, Larisa
Published in Clinical pharmacology in drug development (01.07.2022)
Published in Clinical pharmacology in drug development (01.07.2022)
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Journal Article
First‐in‐Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E6742, a Dual Antagonist of Toll‐like Receptors 7 and 8, in Healthy Volunteers
Yamakawa, Naoto, Tago, Fumitoshi, Nakai, Kenya, Kitahara, Yasumi, Ikari, Shingo, Hojo, Seiichiro, Hall, Nancy, Aluri, Jagadeesh, Hussein, Ziad, Gevorkyan, Hakop, Maruyama, Tatsuya, Ishizaka, Sally, Yagi, Takuya
Published in Clinical pharmacology in drug development (01.04.2023)
Published in Clinical pharmacology in drug development (01.04.2023)
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Journal Article