TRPV4 Channels stimulate Ca²⁺-induced Ca²⁺ release in astrocytic endfeet and amplify neurovascular coupling responses
Dunn, Kathryn M., Hill-Eubanks, David C., Liedtke, Wolfgang B., Nelson, Mark T.
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2013)
Get full text
Journal Article
Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage
Lee, Whasil, Leddy, Holly A, Chen, Yong, Lee, Suk Hee, Zelenski, Nicole A, McNulty, Amy L, Wu, Jason, Beicker, Kellie N, Coles, Jeffrey, Zauscher, Stefan, Grandl, Jörg, Sachs, Frederick, Guilak, Farshid, Liedtke, Wolfgang B
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2014)
Get full text
Journal Article
Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch
Chen, Yong, Fang, Quan, Wang, Zilong, Zhang, Jennifer Y., MacLeod, Amanda S., Hall, Russell P., Liedtke, Wolfgang B.
Published in The Journal of biological chemistry (06.05.2016)
Published in The Journal of biological chemistry (06.05.2016)
Get full text
Journal Article
UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling
Moore, Carlene, Cevikbas, Ferda, Pasolli, H Amalia, Chen, Yong, Kong, Wei, Kempkes, Cordula, Parekh, Puja, Lee, Suk Hee, Kontchou, Nelly-Ange, Yeh, Iwei, Ye, Iwei, Jokerst, Nan Marie, Fuchs, Elaine, Steinhoff, Martin, Liedtke, Wolfgang B
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2013)
Get full text
Journal Article
Elementary Ca²⁺ Signals Through Endothelial TRPV4 Channels Regulate Vascular Function
Sonkusare, Swapnil K., Bonev, Adrian D., Ledoux, Jonathan, Liedtke, Wolfgang, Kotlikoff, Michael I., Heppner, Thomas J., Hill-Eubanks, David C., Nelson, Mark T.
Published in Science (American Association for the Advancement of Science) (04.05.2012)
Published in Science (American Association for the Advancement of Science) (04.05.2012)
Get full text
Journal Article
A craniofacial-specific monosynaptic circuit enables heightened affective pain
Rodriguez, Erica, Sakurai, Katsuyasu, Xu, Jennie, Chen, Yong, Toda, Koji, Zhao, Shengli, Han, Bao-Xia, Ryu, David, Yin, Henry, Liedtke, Wolfgang, Wang, Fan
Published in Nature neuroscience (01.12.2017)
Published in Nature neuroscience (01.12.2017)
Get full text
Journal Article
Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain
Zhao, Peishen, Lieu, TinaMarie, Barlow, Nicholas, Sostegni, Silvia, Haerteis, Silke, Korbmacher, Christoph, Liedtke, Wolfgang, Jimenez-Vargas, Nestor N., Vanner, Stephen J., Bunnett, Nigel W.
Published in The Journal of biological chemistry (29.05.2015)
Published in The Journal of biological chemistry (29.05.2015)
Get full text
Journal Article
Local Peroxynitrite Impairs Endothelial Transient Receptor Potential Vanilloid 4 Channels and Elevates Blood Pressure in Obesity
Ottolini, Matteo, Hong, Kwangseok, Cope, Eric L, Daneva, Zdravka, DeLalio, Leon J, Sokolowski, Jennifer D, Marziano, Corina, Nguyen, Nhiem Y, Altschmied, Joachim, Haendeler, Judith, Johnstone, Scott R, Kalani, Mohammad Y, Park, Min S, Patel, Rakesh P, Liedtke, Wolfgang, Isakson, Brant E, Sonkusare, Swapnil K
Published in Circulation (New York, N.Y.) (21.04.2020)
Published in Circulation (New York, N.Y.) (21.04.2020)
Get full text
Journal Article
Abnormal Osmotic Regulation in trpv4-/-Mice
Liedtke, Wolfgang, Friedman, Jeffrey M.
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2003)
Get full text
Journal Article
Type VI Collagen Regulates Pericellular Matrix Properties, Chondrocyte Swelling, and Mechanotransduction in Mouse Articular Cartilage
Zelenski, Nicole A., Leddy, Holly A., Sanchez‐Adams, Johannah, Zhang, Jinzi, Bonaldo, Paolo, Liedtke, Wolfgang, Guilak, Farshid
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2015)
Get full text
Journal Article
Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter
Yeo, Michele, Berglund, Ken, Hanna, Michael, Guo, Junjie U., Kittur, Jaya, Torres, Maria D., Abramowitz, Joel, Busciglio, Jorge, Gao, Yuan, Birnbaumer, Lutz, Liedtke, Wolfgang B.
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2013)
Get full text
Journal Article
Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity
Kanugula, Anantha K., Adapala, Ravi K., Jamaiyar, Anurag, Lenkey, Nina, Guarino, Brianna D., Liedtke, Wolfgang, Yin, Liya, Paruchuri, Sailaja, Thodeti, Charles K.
Published in Angiogenesis (London) (01.08.2021)
Published in Angiogenesis (London) (01.08.2021)
Get full text
Journal Article
Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission
Yeo, Michele, Chen, Yong, Jiang, Changyu, Chen, Gang, Wang, Kaiyuan, Chandra, Sharat, Bortsov, Andrey, Lioudyno, Maria, Zeng, Qian, Wang, Peng, Wang, Zilong, Busciglio, Jorge, Ji, Ru-Rong, Liedtke, Wolfgang
Published in Nature communications (27.10.2021)
Published in Nature communications (27.10.2021)
Get full text
Journal Article
TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure
Earley, Scott, Pauyo, Thierry, Drapp, Rebecca, Tavares, Matthew J, Liedtke, Wolfgang, Brayden, Joseph E
Published in American journal of physiology. Heart and circulatory physiology (01.09.2009)
Published in American journal of physiology. Heart and circulatory physiology (01.09.2009)
Get full text
Journal Article
Protease-activated Receptor 2 (PAR2) Protein and Transient Receptor Potential Vanilloid 4 (TRPV4) Protein Coupling Is Required for Sustained Inflammatory Signaling
Poole, Daniel P., Amadesi, Silvia, Veldhuis, Nicholas A., Abogadie, Fe C., Lieu, TinaMarie, Darby, William, Liedtke, Wolfgang, Lew, Michael J., McIntyre, Peter, Bunnett, Nigel W.
Published in The Journal of biological chemistry (22.02.2013)
Published in The Journal of biological chemistry (22.02.2013)
Get full text
Journal Article
TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis
Ye, Li, Kleiner, Sandra, Wu, Jun, Sah, Rajan, Gupta, Rana K, Banks, Alexander S, Cohen, Paul, Khandekar, Melin J, Boström, Pontus, Mepani, Rina J, Laznik, Dina, Kamenecka, Theodore M, Song, Xinyi, Liedtke, Wolfgang, Mootha, Vamsi K, Puigserver, Pere, Griffin, Patrick R, Clapham, David E, Spiegelman, Bruce M
Published in Cell (28.09.2012)
Published in Cell (28.09.2012)
Get full text
Journal Article
TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor
Chen, Yong, Kanju, Patrick, Fang, Quan, Lee, Suk Hee, Parekh, Puja K., Lee, Whasil, Moore, Carlene, Brenner, Daniel, Gereau, Robert W., Wang, Fan, Liedtke, Wolfgang
Published in Pain (Amsterdam) (01.12.2014)
Published in Pain (Amsterdam) (01.12.2014)
Get full text
Journal Article
The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells
Ryskamp, Daniel A, Witkovsky, Paul, Barabas, Peter, Huang, Wei, Koehler, Christopher, Akimov, Nikolay P, Lee, Suk Hee, Chauhan, Shiwani, Xing, Wei, Rentería, René C, Liedtke, Wolfgang, Krizaj, David
Published in The Journal of neuroscience (11.05.2011)
Published in The Journal of neuroscience (11.05.2011)
Get full text
Journal Article