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Published in Cell stem cell (07.07.2016)
Published in Cell stem cell (07.07.2016)
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Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression
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Published in Cell (07.09.2017)
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ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression
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SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition
Kim, Eunhee, Ilagan, Janine O., Liang, Yang, Daubner, Gerrit M., Lee, Stanley C.-W., Ramakrishnan, Aravind, Li, Yue, Chung, Young Rock, Micol, Jean-Baptiste, Murphy, Michele E., Cho, Hana, Kim, Min-Kyung, Zebari, Ahmad S., Aumann, Shlomzion, Park, Christopher Y., Buonamici, Silvia, Smith, Peter G., Deeg, H. Joachim, Lobry, Camille, Aifantis, Iannis, Modis, Yorgo, Allain, Frederic H.-T., Halene, Stephanie, Bradley, Robert K., Abdel-Wahab, Omar
Published in Cancer cell (11.05.2015)
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Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia
Li, Sheng, Garrett-Bakelman, Francine E, Chung, Stephen S, Sanders, Mathijs A, Hricik, Todd, Rapaport, Franck, Patel, Jay, Dillon, Richard, Vijay, Priyanka, Brown, Anna L, Perl, Alexander E, Cannon, Joy, Bullinger, Lars, Luger, Selina, Becker, Michael, Lewis, Ian D, To, Luen Bik, Delwel, Ruud, Löwenberg, Bob, Döhner, Hartmut, Döhner, Konstanze, Guzman, Monica L, Hassane, Duane C, Roboz, Gail J, Grimwade, David, Valk, Peter J M, D'Andrea, Richard J, Carroll, Martin, Park, Christopher Y, Neuberg, Donna, Levine, Ross, Melnick, Ari M, Mason, Christopher E
Published in Nature medicine (01.07.2016)
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Therapeutic Antibody Targeting of CD47 Eliminates Human Acute Lymphoblastic Leukemia
CHAO, Mark P, ALIZADEH, Ash A, TANG, Chad, JAN, Max, WEISSMAN-TSUKAMOTO, Rachel, FEIFEI ZHAO, PARK, Christopher Y, WEISSMAN, Irving L, MAJETI, Ravindra
Published in Cancer research (Chicago, Ill.) (15.02.2011)
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Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47
Chao, Mark P, Jaiswal, Siddhartha, Weissman-Tsukamoto, Rachel, Alizadeh, Ash A, Gentles, Andrew J, Volkmer, Jens, Weiskopf, Kipp, Willingham, Stephen B, Raveh, Tal, Park, Christopher Y, Majeti, Ravindra, Weissman, Irving L
Published in Science translational medicine (22.12.2010)
Published in Science translational medicine (22.12.2010)
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CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis
Jaiswal, Siddhartha, Jamieson, Catriona H.M., Pang, Wendy W., Park, Christopher Y., Chao, Mark P., Majeti, Ravindra, Traver, David, van Rooijen, Nico, Weissman, Irving L.
Published in Cell (23.07.2009)
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Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice
Pang, Wendy W., Czechowicz, Agnieszka, Logan, Aaron C., Bhardwaj, Rashmi, Poyser, Jessica, Park, Christopher Y., Weissman, Irving L., Shizuru, Judith A.
Published in Blood (09.05.2019)
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Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo
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Published in The Journal of experimental medicine (18.11.2013)
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microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia
Han, Yoon-Chi, Park, Christopher Y, Bhagat, Govind, Zhang, Jinping, Wang, Yulei, Fan, Jian-Bing, Liu, Mofang, Zou, Yongrui, Weissman, Irving L, Gu, Hua
Published in The Journal of experimental medicine (15.03.2010)
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CD99 is a therapeutic target on disease stem cells in myeloid malignancies
Chung, Stephen S, Eng, William S, Hu, Wenhuo, Khalaj, Mona, Garrett-Bakelman, Francine E, Tavakkoli, Montreh, Levine, Ross L, Carroll, Martin, Klimek, Virginia M, Melnick, Ari M, Park, Christopher Y
Published in Science translational medicine (25.01.2017)
Published in Science translational medicine (25.01.2017)
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Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells
Durham, Benjamin H., Roos-Weil, Damien, Baillou, Claude, Cohen-Aubart, Fleur, Yoshimi, Akihide, Miyara, Makoto, Papo, Matthias, Hélias-Rodzewicz, Zofia, Terrones, Nathalie, Ozkaya, Neval, Dogan, Ahmet, Rampal, Raajit, Urbain, Fanny, Le Fèvre, Lucie, Diamond, Eli L., Park, Christopher Y., Papo, Thomas, Charlotte, Frédéric, Gorochov, Guy, Taly, Valérie, Bernard, Olivier A., Amoura, Zahir, Abdel-Wahab, Omar, Lemoine, François M., Haroche, Julien, Emile, Jean-François
Published in Blood (13.07.2017)
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ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity
Moore, Michael J, Blachere, Nathalie E, Fak, John J, Park, Christopher Y, Sawicka, Kirsty, Parveen, Salina, Zucker-Scharff, Ilana, Moltedo, Bruno, Rudensky, Alexander Y, Darnell, Robert B
Published in eLife (31.05.2018)
Published in eLife (31.05.2018)
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PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage
Hwang, Hun-Way, Park, Christopher Y., Goodarzi, Hani, Fak, John J., Mele, Aldo, Moore, Michael J., Saito, Yuhki, Darnell, Robert B.
Published in Cell reports (Cambridge) (12.04.2016)
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Notch pathway activation targets AML-initiating cell homeostasis and differentiation
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Published in The Journal of experimental medicine (11.02.2013)
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FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory
Sawicka, Kirsty, Hale, Caryn R, Park, Christopher Y, Fak, John J, Gresack, Jodi E, Van Driesche, Sarah J, Kang, Jin Joo, Darnell, Jennifer C, Darnell, Robert B
Published in eLife (20.12.2019)
Published in eLife (20.12.2019)
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