Editorial: How does exercise modify the course of Alzheimer's disease?
Arciero, Paul J, Grasso, Patricia, Anderson-Hanley, Cay, Zimmerman, Earl
Published in Frontiers in aging neuroscience (11.01.2023)
Published in Frontiers in aging neuroscience (11.01.2023)
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Journal Article
MA-[D-Leu-4]-OB3, a small molecule synthetic peptide leptin mimetic, improves episodic memory, and reduces serum levels of tumor necrosis factor-alpha and neurodegeneration in mouse models of Type 1 and Type 2 Diabetes Mellitus
Hirschstein, Zall, Vanga, Gautam Reddy, Wang, Guirong, Novakovic, Zachary M., Grasso, Patricia
Published in Biochimica et biophysica acta. General subjects (01.11.2020)
Published in Biochimica et biophysica acta. General subjects (01.11.2020)
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[D-Leu-4]-OB3 and MA-[D-Leu-4]-OB3, small molecule synthetic peptide leptin mimetics, improve glycemic control in diet-induced obese (DIO) mice
Wang, Anke, Anderson, Brian M., Novakovic, Zachary M., Grasso, Patricia
Published in Peptides (New York, N.Y. : 1980) (01.03.2018)
Published in Peptides (New York, N.Y. : 1980) (01.03.2018)
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Prophylactic Application of MA-[d-Leu-4]-OB3, a Small Molecule Synthetic Peptide Leptin Mimetic, Prevents or Slows the Progression of Obesity, Insulin Resistance, and Cognitive Impairment in a Mouse Model of Type 2 Diabetes Mellitus
Chua, Fu Yee, Novakovic, Zachary M., Grasso, Patricia
Published in International journal of peptide research and therapeutics (01.12.2021)
Published in International journal of peptide research and therapeutics (01.12.2021)
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Journal Article
MA-[D-Leu-4]-OB3, a Small Molecule Synthetic Peptide Leptin Mimetic, Normalizes Glucose Tolerance and Episodic Memory in a Mouse Model of Type 2 Diabetes Mellitus and Alzheimer’s Disease-Like Cognitive Impairment
Hirschstein, Zall, Novakovic, Zachary M., Grasso, Patricia
Published in International journal of peptide research and therapeutics (01.12.2020)
Published in International journal of peptide research and therapeutics (01.12.2020)
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Journal Article
MA-[d-Leu-4]-OB3, a Small Molecule Synthetic Peptide Leptin Mimetic, Mirrors the Cognitive Enhancing Action of Leptin in a Mouse Model of Type 1 Diabetes Mellitus and Alzheimer’s Disease-Like Cognitive Impairment
Anderson, Brian M., Hirschstein, Zall, Novakovic, Zachary M., Grasso, Patricia
Published in International journal of peptide research and therapeutics (01.09.2020)
Published in International journal of peptide research and therapeutics (01.09.2020)
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Journal Article
MA-[D-Leu-4)-OB3, a Small Molecule Synthetic Peptide Leptin Mimetic, Improves Serum Lipid Profiles in Mouse Models of Type 1 and Type 2 Diabetes Mellitus
Hirschstein, Zall, Wang, Anke, Anderson, Brian M., Novakovic, Zachary M., Grasso, Patricia
Published in International journal of peptide research and therapeutics (01.06.2021)
Published in International journal of peptide research and therapeutics (01.06.2021)
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Journal Article
Myristic acid conjugation of [D-Leu-4]-OB3, a biologically active leptin-related synthetic peptide amide, significantly improves its pharmacokinetic profile and efficacy
Novakovic, Zachary M., Anderson, Brian M., Grasso, Patricia
Published in Peptides (New York, N.Y. : 1980) (01.12.2014)
Published in Peptides (New York, N.Y. : 1980) (01.12.2014)
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Journal Article
[D-Leu-4]-OB3, an orally bioavailable leptin-related synthetic peptide insulin sensitizer: A study comparing the efficacies of [D-Leu-4]-OB3 and metformin on energy balance and glycemic regulation in insulin-deficient male Swiss Webster mice
Novakovic, Zachary M., Leinung, Matthew C., Grasso, Patricia
Published in Peptides (New York, N.Y. : 1980) (01.05.2013)
Published in Peptides (New York, N.Y. : 1980) (01.05.2013)
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Journal Article
Leptin-derived peptides block leptin-induced proliferation by reducing expression of pro-inflammatory genes in hepatocellular carcinoma cells
Ho, Yih, Wang, Shwu-Huey, Chen, Yi-Ru, Li, Zi-Lin, Chin, Yu-Tang, Yang, Yu-Chen S.H., Wu, Yun-Hsuan, Su, Kuan-Wei, Chu, Hung-Ru, Chiu, Hsien-Chung, Crawford, Dana R., Shih, Ya-Jung, Grasso, Patricia, Tang, Heng-Yuan, Lin, Hung-Yun, Davis, Paul J., Whang-Peng, Jacqueline, Wang, Kuan
Published in Food and chemical toxicology (01.11.2019)
Published in Food and chemical toxicology (01.11.2019)
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Journal Article
Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin
Yang, Yu-Chen Sh, Chin, Yu-Tang, Hsieh, Meng-Ti, Lai, Hsuan-Yu, Ke, Chien-Chih, Crawford, Dana R, Lee, Oscar K, Fu, Earl, Mousa, Shaker A, Grasso, Patricia, Liu, Leroy F, Chang, Heng-Yu, Tang, Heng-Yuan, Lin, Hung-Yun, Davis, Paul J
Published in Oncotarget (10.05.2016)
Published in Oncotarget (10.05.2016)
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Intranasal administration of mouse [D-Leu-4]OB3, a synthetic peptide amide with leptin-like activity, enhances total uptake and bioavailability in Swiss Webster mice when compared to intraperitoneal, subcutaneous, and intramuscular delivery systems
Novakovic, Zachary M., Leinung, Matthew C., Lee, Daniel W., Grasso, Patricia
Published in Regulatory peptides (10.04.2009)
Published in Regulatory peptides (10.04.2009)
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