Deletion of tissue factor pathway inhibitor isoform beta or gamma, but not alpha, improves clotting in hemophilic mice
Eldem, Irem, Antunes-Heck, Lilian, Subramanian, Renumathi, Lasky, Nina M., Ashworth, Katrina, Di Paola, Jorge, Girard, Thomas J.
Published in Journal of thrombosis and haemostasis (01.10.2024)
Published in Journal of thrombosis and haemostasis (01.10.2024)
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Peripheral blood mononuclear cell tissue factor (F3 gene) transcript levels and circulating extracellular vesicles are elevated in severe coronavirus 2019 (COVID-19) disease
Girard, Thomas J., Antunes, Lilian, Zhang, Nan, Amrute, Junedh M., Subramanian, Renumathi, Eldem, Irem, Remy, Kenneth E., Mazer, Monty, Erlich, Emma C., Cruchaga, Carlos, Steed, Ashley L., Randolph, Gwendalyn J., Di Paola, Jorge
Published in Journal of thrombosis and haemostasis (01.03.2023)
Published in Journal of thrombosis and haemostasis (01.03.2023)
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Journal Article
Design, Parallel Synthesis, and Crystal Structures of Pyrazinone Antithrombotics as Selective Inhibitors of the Tissue Factor VIIa Complex
Parlow, John J, Case, Brenda L, Dice, Thomas A, Fenton, Ricky L, Hayes, Michael J, Jones, Darin E, Neumann, William L, Wood, Rhonda S, Lachance, Rhonda M, Girard, Thomas J, Nicholson, Nancy S, Clare, Michael, Stegeman, Roderick A, Stevens, Anna M, Stallings, William C, Kurumbail, Ravi G, South, Michael S
Published in Journal of medicinal chemistry (11.09.2003)
Published in Journal of medicinal chemistry (11.09.2003)
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Journal Article
Factor V, tissue factor pathway inhibitor, and east Texas bleeding disorder
Broze, Jr, George J, Girard, Thomas J
Published in The Journal of clinical investigation (01.09.2013)
Published in The Journal of clinical investigation (01.09.2013)
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Journal Article
Regulation of coagulation by a multivalent Kunitz-type inhibitor
Broze, George J, Girard, Thomas J, Novotny, William F
Published in Biochemistry (Easton) (01.08.1990)
Published in Biochemistry (Easton) (01.08.1990)
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Journal Article
Inhibitory Activity of Unsaturated Fatty Acids and Anacardic Acids toward Soluble Tissue Factor−Factor VIIa Complex
Wang, Dandan, Girard, Thomas J, Kasten, Thomas P, LaChance, Rhonda M, Miller-Wideman, Margaret A, Durley, Richard C
Published in Journal of natural products (Washington, D.C.) (01.11.1998)
Published in Journal of natural products (Washington, D.C.) (01.11.1998)
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Journal Article
Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex
South, Michael S., Case, Brenda L., Wood, Rhonda S., Jones, Darin E., Hayes, Michael J., Girard, Thomas J., Lachance, Rhonda M., Nicholson, Nancy S., Clare, Michael, Stevens, Anna M., Stegeman, Roderick A., Stallings, William C., Kurumbail, Ravi G., Parlow, John J.
Published in Bioorganic & medicinal chemistry letters (21.07.2003)
Published in Bioorganic & medicinal chemistry letters (21.07.2003)
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Journal Article
Polymer-Assisted Solution-Phase Library Synthesis and Crystal Structure of α-Ketothiazoles as Tissue Factor VIIa Inhibitors
Parlow, John J, Dice, Thomas A, Lachance, Rhonda M, Girard, Thomas J, Stevens, Anna M, Stegeman, Roderick A, Stallings, William C, Kurumbail, Ravi G, South, Michael S
Published in Journal of medicinal chemistry (11.09.2003)
Published in Journal of medicinal chemistry (11.09.2003)
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Journal Article
Polymer-Assisted solution-Phase (PASP) parallel synthesis of an α-Ketothiazole library as tissue factor VIIa inhibitors
South, Michael S, Dice, Thomas A, Girard, Thomas J, Lachance, Rhonda M, Stevens, Anna M, Stegeman, Roderick A, Stallings, William C, Kurumbail, Ravi G, Parlow, John J
Published in Bioorganic & medicinal chemistry letters (21.07.2003)
Published in Bioorganic & medicinal chemistry letters (21.07.2003)
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Journal Article
Pharmacological intervention at disparate sites in the coagulation cascade: Comparison of anti-thrombotic efficacy vs. bleeding propensity in a rat model of acute arterial thrombosis
SZALONY, James A, TAITE, Beatrice B, GIRARD, Thomas J, NICHOLSON, Nancy S, LACHANCE, Rhonda M
Published in Journal of thrombosis and thrombolysis (01.10.2002)
Published in Journal of thrombosis and thrombolysis (01.10.2002)
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Journal Article
Suppressing protein Z‐dependent inhibition of factor Xa improves coagulation in hemophilia A
Girard, T. J., Lasky, N. M., Grunz, K., Broze, G. J.
Published in Journal of thrombosis and haemostasis (01.01.2019)
Published in Journal of thrombosis and haemostasis (01.01.2019)
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Journal Article
Piperazinyl Glutamate Pyridines as Potent Orally Bioavailable P2Y(12) Antagonists for Inhibition of Platelet Aggregation
Parlow, John J., Burney, Mary W., Case, Brenda L., Girard, Thomas J., Hall, Kerri A., Harris, Peter K., Hiebsch, Ronald R., Huff, Rita M., Lachance, Rhonda M., Mischke, Deborah A., Rapp, Stephen R., Woerndle, Rhonda S., Ennis, Michael D.
Published in Journal of medicinal chemistry (11.03.2010)
Published in Journal of medicinal chemistry (11.03.2010)
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Journal Article
Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation
Cross, A H, Girard, T J, Giacoletto, K S, Evans, R J, Keeling, R M, Lin, R F, Trotter, J L, Karr, R W
Published in The Journal of clinical investigation (01.06.1995)
Published in The Journal of clinical investigation (01.06.1995)
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