Aminopyridine-Based c-Jun N-Terminal Kinase Inhibitors with Cellular Activity and Minimal Cross-Kinase Activity
Szczepankiewicz, Bruce G, Kosogof, Christi, Nelson, Lissa T. J, Liu, Gang, Liu, Bo, Zhao, Hongyu, Serby, Michael D, Xin, Zhili, Liu, Mei, Gum, Rebecca J, Haasch, Deanna L, Wang, Sanyi, Clampit, Jill E, Johnson, Eric F, Lubben, Thomas H, Stashko, Michael A, Olejniczak, Edward T, Sun, Chaohong, Dorwin, Sarah A, Haskins, Kristi, Abad-Zapatero, Cele, Fry, Elizabeth H, Hutchins, Charles W, Sham, Hing L, Rondinone, Cristina M, Trevillyan, James M
Published in Journal of medicinal chemistry (15.06.2006)
Published in Journal of medicinal chemistry (15.06.2006)
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Journal Article
Reduction of Protein Tyrosine Phosphatase 1B Increases Insulin-Dependent Signaling in ob/ob Mice
GUM, Rebecca J, GAEDE, Lori L, KOTERSKI, Sandra L, HEINDEL, Matthew, CLAMPIT, Jill E, ZINKER, Bradley A, TREVILLYAN, James M, ULRICH, Roger G, JIROUSEK, Michael R, RONDINONE, Cristina M
Published in Diabetes (New York, N.Y.) (01.01.2003)
Published in Diabetes (New York, N.Y.) (01.01.2003)
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Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases
Comess, Kenneth M, Sun, Chaohong, Abad-Zapatero, Cele, Goedken, Eric R, Gum, Rebecca J, Borhani, David W, Argiriadi, Maria, Groebe, Duncan R, Jia, Yong, Clampit, Jill E, Haasch, Deanna L, Smith, Harriet T, Wang, Sanyi, Song, Danying, Coen, Michael L, Cloutier, Timothy E, Tang, Hua, Cheng, Xueheng, Quinn, Christopher, Liu, Bo, Xin, Zhili, Liu, Gang, Fry, Elizabeth H, Stoll, Vincent, Ng, Teresa I, Banach, David, Marcotte, Doug, Burns, David J, Calderwood, David J, Hajduk, Philip J
Published in ACS chemical biology (18.03.2011)
Published in ACS chemical biology (18.03.2011)
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Journal Article
Developmental Switch from Prolonged Insulin Action to Increased Insulin Sensitivity in Protein Tyrosine Phosphatase 1B-Deficient Hepatocytes
Gonzalez-Rodriguez, Agueda, Clampit, Jill E, Escribano, Oscar, Benito, Manuel, Rondinone, Cristina M, Valverde, Angela M
Published in Endocrinology (Philadelphia) (01.02.2007)
Published in Endocrinology (Philadelphia) (01.02.2007)
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Journal Article
Discovery of Potent, Highly Selective, and Orally Bioavailable Pyridine Carboxamide c-Jun NH2-Terminal Kinase Inhibitors
Zhao, Hongyu, Serby, Michael D, Xin, Zhili, Szczepankiewicz, Bruce G, Liu, Mei, Kosogof, Christi, Liu, Bo, Nelson, Lissa T. J, Johnson, Eric F, Wang, Sanyi, Pederson, Terry, Gum, Rebecca J, Clampit, Jill E, Haasch, Deanna L, Abad-Zapatero, Cele, Fry, Elizabeth H, Rondinone, Cristina, Trevillyan, James M, Sham, Hing L, Liu, Gang
Published in Journal of medicinal chemistry (27.07.2006)
Published in Journal of medicinal chemistry (27.07.2006)
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Journal Article
Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies
Liu, Mei, Wang, Sanyi, Clampit, Jill E., Gum, Rebecca J., Haasch, Deanna L., Rondinone, Cristina M., Trevillyan, James M., Abad-Zapatero, Cele, Fry, Elizabeth H., Sham, Hing L., Liu, Gang
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
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Journal Article
Protein Tyrosine Phosphatase 1B Reduction Regulates Adiposity and Expression of Genes Involved in Lipogenesis
RONDINONE, Cristina M, TREVILLYAN, James M, BUTLER, Madeline, MONIA, Brett P, JIROUSEK, Michael R, WARING, Jeffrey F, CLAMPIT, Jill, GUM, Rebecca J, BERG, Cathy, KROEGER, Paul, FROST, Leigh, ZINKER, Bradley A, REILLY, Regina, ULRICH, Roger
Published in Diabetes (New York, N.Y.) (01.08.2002)
Published in Diabetes (New York, N.Y.) (01.08.2002)
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Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors
Liu, Mei, Xin, Zhili, Clampit, Jill E., Wang, Sanyi, Gum, Rebecca J., Haasch, Deanna L., Trevillyan, James M., Abad-Zapatero, Cele, Fry, Elizabeth H., Sham, Hing L., Liu, Gang
Published in Bioorganic & medicinal chemistry letters (15.05.2006)
Published in Bioorganic & medicinal chemistry letters (15.05.2006)
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Journal Article
Aminopyridine carboxamides as c-Jun N-terminal kinase inhibitors: Targeting the gatekeeper residue and beyond
Liu, Gang, Zhao, Hongyu, Liu, Bo, Xin, Zhili, Liu, Mei, Kosogof, Christi, Szczepankiewicz, Bruce G., Wang, Sanyi, Clampit, Jill E., Gum, Rebecca J., Haasch, Deanna L., Trevillyan, James M., Sham, Hing L.
Published in Bioorganic & medicinal chemistry letters (15.11.2006)
Published in Bioorganic & medicinal chemistry letters (15.11.2006)
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Journal Article
Reduction of protein-tyrosine phosphatase-1B increases insulin signaling in FAO hepatoma cells
Clampit, Jill E, Meuth, Joseph L, Smith, Harriet T, Reilly, Regina M, Jirousek, Michael R, Trevillyan, James M, Rondinone, Cristina M
Published in Biochemical and biophysical research communications (10.01.2003)
Published in Biochemical and biophysical research communications (10.01.2003)
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Journal Article
PTP1B antisense-treated mice show regulation of genes involved in lipogenesis in liver and fat
Waring, Jeffrey F., Ciurlionis, Rita, Clampit, Jill E., Morgan, Sherry, Gum, Rebecca J., Jolly, Robert A., Kroeger, Paul, Frost, Leigh, Trevillyan, James, Zinker, Bradley A., Jirousek, Michael, Ulrich, Roger G., Rondinone, Cristina M.
Published in Molecular and cellular endocrinology (30.05.2003)
Published in Molecular and cellular endocrinology (30.05.2003)
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Journal Article
Reduction of PTP1B induces differential expression of PI3-kinase (p85α) isoforms
Rondinone, Cristina M., Clampit, Jill, Gum, Rebecca J., Zinker, Bradley A., Jirousek, Michael R., Trevillyan, James M.
Published in Biochemical and biophysical research communications (15.10.2004)
Published in Biochemical and biophysical research communications (15.10.2004)
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Journal Article
Putting Thought to Paper: A μARCS Protease Screen
Groebe, Duncan R., Maus, Mary L., Pederson, Terry, Clampit, Jill, Djuric, Stevan, Trevillyan, James, Lin, Chun W., Burns, David J., Warrior, Usha
Published in SLAS discovery (01.12.2003)
Published in SLAS discovery (01.12.2003)
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