(3S,4R)-3-에틸-4-(3H-이미다조[1,2-a]피롤로[2,3-e]-피라진-8-일)-N-피롤리딘-1-카복스아미드 및 이의 고체상 형태의 제조 방법
ALLIAN AYMAN D, OTHMAN AHMED A, BHAGAVATULA LAKSHMI, MULHERN MATHEW M, MARROUM PATRICK J, BORCHARDT THOMAS B, NORDSTROEM LARS F, SHEIKH AHMAD Y, MOHAMED MOHAMED ESLAM F, ROZEMA MICHAEL J, MAYER PETER T, JAYANTH JAYANTHY
Year of Publication 16.07.2018
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Year of Publication 16.07.2018
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Processes for the preparation of (3s,4r)-3-ethyl-4-(3h-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
NORDSTROEM Lars F, SHEIKH Ahmad Y, MULHERN Mathew M, BORCHARDT Thomas B, MOHAMED Mohamed-Eslam F, ROZEMA Michael J, MAYER Peter T, JAYANTH Jayanthy, ALLIAN Ayman D, BHAGAVATULA Lakshmi, MARROUM Patrick J, OTHMAN Ahmed A
Year of Publication 01.09.2024
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Year of Publication 01.09.2024
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y
Year of Publication 01.02.2024
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Year of Publication 01.02.2024
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Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
JAYANTH, Jayanthy, OTHMAN, Ahmed A, MAYER, Peter T, BORCHARDT, Thomas B, KLÜNDER, Ben, MULHERN, Mathew M, ROZEMA, Michael J, SHEIKH, Ahmad Y, MOHAMED, Mohamed-Eslam F, NORDSTROM, Fredrik Lars, BHAGAVATULA, Lakshmi, MARROUM, Patrick J, ALLIAN, Ayman D
Year of Publication 09.11.2023
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Year of Publication 09.11.2023
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Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
JAYANTH, Jayanthy, OTHMAN, Ahmed A, MAYER, Peter T, BORCHARDT, Thomas B, KLÜNDER, Ben, MULHERN, Mathew M, ROZEMA, Michael J, SHEIKH, Ahmad Y, MOHAMED, Mohamed-Eslam F, NORDSTROM, Fredrik Lars, BHAGAVATULA, Lakshmi, MARROUM, Patrick J, ALLIAN, Ayman D
Year of Publication 02.11.2023
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Year of Publication 02.11.2023
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y
Year of Publication 02.11.2023
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Year of Publication 02.11.2023
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Padley, Robert J, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y, Camp, Heidi S, Voss, Jeffrey W
Year of Publication 26.09.2024
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Year of Publication 26.09.2024
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Rozema, Michael J, Klünder, Ben, Othman, Ahmed A, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy
Year of Publication 19.10.2023
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Year of Publication 19.10.2023
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y
Year of Publication 12.10.2023
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Year of Publication 12.10.2023
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y
Year of Publication 05.10.2023
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Year of Publication 05.10.2023
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y
Year of Publication 05.10.2023
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Year of Publication 05.10.2023
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y
Year of Publication 28.09.2023
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Year of Publication 28.09.2023
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CRYTALLINE L-MALEATE OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-A]PYRROLO[2,3-E]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE
JAYANTH, Jayanthy, OTHMAN, Ahmed A, MAYER, Peter T, BORCHARDT, Thomas B, KLÜNDER, Ben, MULHERN, Mathew M, ROZEMA, Michael J, SHEIKH, Ahmad Y, MOHAMED, Mohamed-Eslam F, NORDSTROM, Fredrik Lars, BHAGAVATULA, Lakshmi, MARROUM, Patrick J, ALLIAN, Ayman D
Year of Publication 02.08.2023
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Year of Publication 02.08.2023
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y
Year of Publication 20.07.2023
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Year of Publication 20.07.2023
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Klunder, Ben, Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Mohamed, Mohamed-Eslam F, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y, Mulhem, Mathew M
Year of Publication 13.07.2023
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Year of Publication 13.07.2023
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Mohamed, Mohamed-Eslam F, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Mulhem, Mathew, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y
Year of Publication 29.06.2023
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Year of Publication 29.06.2023
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Padley, Robert J, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y, Camp, Heidi S, Voss, Jeffrey W
Year of Publication 30.05.2024
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Year of Publication 30.05.2024
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Padley, Robert J, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y, Camp, Heidi S, Voss, Jeffrey W
Year of Publication 23.05.2024
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Year of Publication 23.05.2024
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y
Year of Publication 23.02.2023
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Year of Publication 23.02.2023
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PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Allian, Ayman, Nordstrom, Fredrik Lars, Rozema, Michael J, Othman, Ahmed A, Mohamed, Mohamed-Eslam F, Mulhern, Mathew M, Mayer, Peter T, Borchardt, Thomas B, Jayanth, Jayanthy, Klünder, Ben, Bhagavatula, Lakshmi, Marroum, Patrick J, Sheikh, Ahmad Y
Year of Publication 23.02.2023
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Year of Publication 23.02.2023
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