Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration
Jiang, Ying, Alam, John J., Gomperts, Stephen N., Maruff, Paul, Lemstra, Afina W., Germann, Ursula A., Stavrides, Philip H., Darji, Sandipkumar, Malampati, Sandeep, Peddy, James, Bleiwas, Cynthia, Pawlik, Monika, Pensalfini, Anna, Yang, Dun-Sheng, Subbanna, Shivakumar, Basavarajappa, Balapal S., Smiley, John F., Gardner, Amanda, Blackburn, Kelly, Chu, Hui-May, Prins, Niels D., Teunissen, Charlotte E., Harrison, John E., Scheltens, Philip, Nixon, Ralph A.
Published in Nature communications (21.09.2022)
Published in Nature communications (21.09.2022)
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Marked Calpastatin (CAST) Depletion in Alzheimer's Disease Accelerates Cytoskeleton Disruption and Neurodegeneration: Neuroprotection by CAST Overexpression
Rao, Mala V, Mohan, Panaiyur S, Peterhoff, Corrinne M, Yang, Dun-Sheng, Schmidt, Stephen D, Stavrides, Philip H, Campbell, Jabbar, Chen, Yuanxin, Jiang, Ying, Paskevich, Peter A, Cataldo, Anne M, Haroutunian, Vahram, Nixon, Ralph A
Published in The Journal of neuroscience (19.11.2008)
Published in The Journal of neuroscience (19.11.2008)
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Mature Glycosylation and Trafficking of Nicastrin Modulate Its Binding to Presenilins
Yang, Dun-Sheng, Tandon, Anurag, Chen, Fusheng, Yu, Gang, Yu, Haung, Arawaka, Shigeki, Hasegawa, Hiroshi, Duthie, Monika, Schmidt, Stephen D, Ramabhadran, Triprayer V, Nixon, Ralph A, Mathews, Paul M, Gandy, Samuel E, Mount, Howard T J, St George-Hyslop, Peter, Fraser, Paul E
Published in The Journal of biological chemistry (02.08.2002)
Published in The Journal of biological chemistry (02.08.2002)
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Autophagy and neuronal cell death in neurological disorders
Nixon, Ralph A, Yang, Dun-Sheng
Published in Cold Spring Harbor perspectives in biology (01.10.2012)
Published in Cold Spring Harbor perspectives in biology (01.10.2012)
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Cyclodextrin has conflicting actions on autophagy flux in vivo in brains of normal and Alzheimer model mice
Yang, Dun-Sheng, Stavrides, Philip, Kumar, Asok, Jiang, Ying, Mohan, Panaiyur S, Ohno, Masuo, Dobrenis, Kostantin, Davidson, Cristin D, Saito, Mitsuo, Pawlik, Monika, Huo, Chunfeng, Walkley, Steven U, Nixon, Ralph A
Published in Human molecular genetics (01.03.2017)
Published in Human molecular genetics (01.03.2017)
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Characterization of the Binding of Amyloid‐β Peptide to Cell Culture‐Derived Native Apolipoprotein E2, E3, and E4 Isoforms and to Isoforms from Human Plasma
Yang, Dun‐Sheng, Smith, Jonathan D., Zhou, Zhongmin, Gandy, Samuel E., Martins, Ralph N.
Published in Journal of neurochemistry (01.02.1997)
Published in Journal of neurochemistry (01.02.1997)
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Manipulating the Amyloid-β Aggregation Pathway with Chemical Chaperones
Yang, Dun-Sheng, Yip, Christopher M., Huang, T.H. Jackson, Chakrabartty, Avijit, Fraser, Paul E.
Published in The Journal of biological chemistry (12.11.1999)
Published in The Journal of biological chemistry (12.11.1999)
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Presenilin structure, function and role in Alzheimer disease
Fraser, Paul E., Yang, Dun-Sheng, Yu, Gang, Lévesque, Lyne, Nishimura, Masaki, Arawaka, Shigeki, Serpell, Louise C., Rogaeva, Ekaterina, St George-Hyslop, Peter
Published in Biochimica et biophysica acta (26.07.2000)
Published in Biochimica et biophysica acta (26.07.2000)
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Presenilin function: connections to Alzheimer's disease and signal transduction
Fraser, P E, Yu, G, Lévesque, L, Nishimura, M, Yang, D S, Mount, H T, Westaway, D, St George-Hyslop, P H
Published in Biochemical Society Symposia (01.01.2001)
Published in Biochemical Society Symposia (01.01.2001)
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All or none fibrillogenesis of a prion peptide
Zou, Wen‐Quan, Yang, Dun‐Sheng, Fraser, Paul E., Cashman, Neil R., Chakrabartty, Avijit
Published in European journal of biochemistry (01.09.2001)
Published in European journal of biochemistry (01.09.2001)
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