Brain cell type-specific enhancer-promoter interactome maps and disease - risk association
Nott, Alexi, Holtman, Inge R, Coufal, Nicole G, Schlachetzki, Johannes C M, Yu, Miao, Hu, Rong, Han, Claudia Z, Pena, Monique, Xiao, Jiayang, Wu, Yin, Keulen, Zahara, Pasillas, Martina P, O'Connor, Carolyn, Nickl, Christian K, Schafer, Simon T, Shen, Zeyang, Rissman, Robert A, Brewer, James B, Gosselin, David, Gonda, David D, Levy, Michael L, Rosenfeld, Michael G, McVicker, Graham, Gage, Fred H, Ren, Bing, Glass, Christopher K
Published in Science (American Association for the Advancement of Science) (29.11.2019)
Published in Science (American Association for the Advancement of Science) (29.11.2019)
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Transplantation Strategies to Enhance Maturity and Cellular Complexity in Brain Organoids
Wang, Meiyan, Gage, Fred H., Schafer, Simon T.
Published in Biological psychiatry (1969) (01.04.2023)
Published in Biological psychiatry (1969) (01.04.2023)
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Functional Implications of miR-19 in the Migration of Newborn Neurons in the Adult Brain
Han, Jinju, Kim, Hyung Joon, Schafer, Simon T., Paquola, Apua, Clemenson, Gregory D., Toda, Tomohisa, Oh, Jinseo, Pankonin, Aimee R., Lee, Bo Suk, Johnston, Stephen T., Sarkar, Anindita, Denli, Ahmet M., Gage, Fred H.
Published in Neuron (Cambridge, Mass.) (06.07.2016)
Published in Neuron (Cambridge, Mass.) (06.07.2016)
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Cellular complexity in brain organoids: Current progress and unsolved issues
Mansour, Abed AlFatah, Schafer, Simon T., Gage, Fred H.
Published in Seminars in cell & developmental biology (01.03.2021)
Published in Seminars in cell & developmental biology (01.03.2021)
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Journal Article
Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons
Schafer, Simon T., Paquola, Apua C. M., Stern, Shani, Gosselin, David, Ku, Manching, Pena, Monique, Kuret, Thomas J. M., Liyanage, Marvin, Mansour, Abed AlFatah, Jaeger, Baptiste N., Marchetto, Maria C., Glass, Christopher K., Mertens, Jerome, Gage, Fred H.
Published in Nature neuroscience (01.02.2019)
Published in Nature neuroscience (01.02.2019)
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An in vivo neuroimmune organoid model to study human microglia phenotypes
Schafer, Simon T., Mansour, Abed AlFatah, Schlachetzki, Johannes C.M., Pena, Monique, Ghassemzadeh, Saeed, Mitchell, Lisa, Mar, Amanda, Quang, Daphne, Stumpf, Sarah, Ortiz, Irene Santisteban, Lana, Addison J., Baek, Clara, Zaghal, Raghad, Glass, Christopher K., Nimmerjahn, Axel, Gage, Fred H.
Published in Cell (11.05.2023)
Published in Cell (11.05.2023)
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Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients
Mertens, Jerome, Herdy, Joseph R., Traxler, Larissa, Schafer, Simon T., Schlachetzki, Johannes C.M., Böhnke, Lena, Reid, Dylan A., Lee, Hyungjun, Zangwill, Dina, Fernandes, Diana P., Agarwal, Ravi K., Lucciola, Raffaella, Zhou-Yang, Lucia, Karbacher, Lukas, Edenhofer, Frank, Stern, Shani, Horvath, Steve, Paquola, Apua C.M., Glass, Christopher K., Yuan, Shauna H., Ku, Manching, Szücs, Attila, Goldstein, Lawrence S.B., Galasko, Douglas, Gage, Fred H.
Published in Cell stem cell (02.09.2021)
Published in Cell stem cell (02.09.2021)
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Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
Mertens, Jerome, Wang, Qiu-Wen, Kim, Yongsung, Yu, Diana X., Pham, Son, Yang, Bo, Zheng, Yi, Diffenderfer, Kenneth E., Zhang, Jian, Soltani, Sheila, Eames, Tameji, Schafer, Simon T., Boyer, Leah, Marchetto, Maria C., Nurnberger, John I., Calabrese, Joseph R., Oedegaard, Ketil J., McCarthy, Michael J., Zandi, Peter P., Alda, Martin, Nievergelt, Caroline M., Mi, Shuangli, Brennand, Kristen J., Kelsoe, John R., Gage, Fred H., Yao, Jun
Published in Nature (London) (05.11.2015)
Published in Nature (London) (05.11.2015)
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Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons
Reid, Dylan A, Reed, Patrick J, Schlachetzki, Johannes C M, Nitulescu, Ioana I, Chou, Grace, Tsui, Enoch C, Jones, Jeffrey R, Chandran, Sahaana, Lu, Ake T, McClain, Claire A, Ooi, Jean H, Wang, Tzu-Wen, Lana, Addison J, Linker, Sara B, Ricciardulli, Anthony S, Lau, Shong, Schafer, Simon T, Horvath, Steve, Dixon, Jesse R, Hah, Nasun, Glass, Christopher K, Gage, Fred H
Published in Science (American Association for the Advancement of Science) (02.04.2021)
Published in Science (American Association for the Advancement of Science) (02.04.2021)
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Drug interaction between ceftriaxone and theodrenaline/cafedrine : A case example
Werzer, Christina, Schäfer, Simon, Hofmann-Kiefer, Klaus
Published in Die Anaesthesiologie (01.02.2023)
Published in Die Anaesthesiologie (01.02.2023)
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Journal Article
Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA
Krüger, Anne, Oldenburg, Marina, Chebrolu, Chiranjeevi, Beisser, Daniela, Kolter, Julia, Sigmund, Anna M, Steinmann, Jörg, Schäfer, Simon, Hochrein, Hubertus, Rahmann, Sven, Wagner, Hermann, Henneke, Philipp, Hornung, Veit, Buer, Jan, Kirschning, Carsten J
Published in EMBO reports (01.12.2015)
Published in EMBO reports (01.12.2015)
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AQP5-1364A/C polymorphism and the AQP5 expression influence sepsis survival and immune cell migration: a prospective laboratory and patient study
Rump, Katharina, Unterberg, Matthias, Bergmann, Lars, Bankfalvi, Agnes, Menon, Anil, Schäfer, Simon, Scherag, André, Bazzi, Zainab, Siffert, Winfried, Peters, Jürgen, Adamzik, Michael
Published in Journal of translational medicine (21.11.2016)
Published in Journal of translational medicine (21.11.2016)
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Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons
Herdy, Joseph, Schafer, Simon, Kim, Yongsung, Ansari, Zoya, Zangwill, Dina, Ku, Manching, Paquola, Apua, Lee, Hyungjun, Mertens, Jerome, Gage, Fred H
Published in eLife (17.05.2019)
Published in eLife (17.05.2019)
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The NFKB1 Promoter Polymorphism (―94ins/delATTG) Alters Nuclear Translocation of NF-κB1 in Monocytes after Lipopolysaccharide Stimulation and Is Associated with Increased Mortality in Sepsis
ADAMZIK, Michael, SCHAFER, Simon, SIFFERT, Winfried, PETERS, Jürgen, HARTMANN, Matthias, FREY, Ulrich H, BECKER, Arne, KREUZER, Maximiliane, WINNING, Sandra, FREDE, Stilla, STEINMANN, Jörg, FANDREY, Joachim, ZACHAROWSKI, Kai
Published in Anesthesiology (Philadelphia) (2013)
Published in Anesthesiology (Philadelphia) (2013)
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A Phase 1/2 Single-arm Clinical Trial of Recombinant Bacillus Calmette-Guérin (BCG) VPM1002BC Immunotherapy in Non–muscle-invasive Bladder Cancer Recurrence After Conventional BCG Therapy: SAKK 06/14
Rentsch, Cyrill A., Thalmann, George N., Lucca, Ilaria, Kwiatkowski, Maciej, Wirth, Grégory J., Strebel, Räto T., Engeler, Daniel, Pedrazzini, Augusto, Hüttenbrink, Clemens, Schultze-Seemann, Wolfgang, Torpai, Raimund, Bubendorf, Lukas, Wicki, Andreas, Roth, Beat, Bosshard, Piet, Püschel, Heike, Boll, Daniel T., Hefermehl, Lukas, Roghmann, Florian, Gierth, Michael, Ribi, Karin, Schäfer, Simon, Hayoz, Stefanie
Published in European urology oncology (01.04.2022)
Published in European urology oncology (01.04.2022)
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Journal Article
Hydrocortisone fails to abolish NF-κB1 protein nuclear translocation in deletion allele carriers of the NFKB1 promoter polymorphism (-94ins/delATTG) and is associated with increased 30-day mortality in septic shock
Schäfer, Simon T, Gessner, Sophia, Scherag, André, Rump, Katharina, Frey, Ulrich H, Siffert, Winfried, Westendorf, Astrid M, Steinmann, Jörg, Peters, Jürgen, Adamzik, Michael
Published in PloS one (18.08.2014)
Published in PloS one (18.08.2014)
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