Effect of alcohol coadministration on the pharmacodynamics, pharmacokinetics, and safety of lemborexant: A randomized, placebo-controlled crossover study
Landry, Ishani, Hall, Nancy, Aluri, Jagadeesh, Filippov, Gleb, Setnik, Beatrice, Dayal, Satish, Reyderman, Larisa, Moline, Margaret
Published in Journal of psychopharmacology (Oxford) (01.06.2022)
Published in Journal of psychopharmacology (Oxford) (01.06.2022)
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Journal Article
Pharmacokinetics, Pharmacodynamics, and Safety of the Dual Orexin Receptor Antagonist Lemborexant: Findings From Single‐Dose and Multiple‐Ascending‐Dose Phase 1 Studies in Healthy Adults
Landry, Ishani, Nakai, Kenya, Ferry, Jim, Aluri, Jagadeesh, Hall, Nancy, Lalovic, Bojan, Moline, Margaret L.
Published in Clinical pharmacology in drug development (01.02.2021)
Published in Clinical pharmacology in drug development (01.02.2021)
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Journal Article
Effect of Rifampicin on the Pharmacokinetics of Lenvatinib in Healthy Adults
Shumaker, Robert C., Aluri, Jagadeesh, Fan, Jean, Martinez, Gresel, Thompson, Gary A., Ren, Min
Published in Clinical drug investigation (01.09.2014)
Published in Clinical drug investigation (01.09.2014)
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Journal Article
Concentration-Response Modeling of ECG Data From Early-Phase Clinical Studies as an Alternative Clinical and Regulatory Approach to Assessing QT Risk - Experience From the Development Program of Lemborexant
Murphy, Patricia J, Yasuda, Sanae, Nakai, Kenya, Yoshinaga, Takashi, Hall, Nancy, Zhou, Meijian, Aluri, Jagadeesh, Rege, Bhaskar, Moline, Margaret, Ferry, Jim, Darpo, Borje
Published in Journal of clinical pharmacology (01.01.2017)
Published in Journal of clinical pharmacology (01.01.2017)
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Journal Article
Population pharmacokinetic‐pharmacodynamic modeling of serum biomarkers as predictors of tumor dynamics following lenvatinib treatment in patients with radioiodine‐refractory differentiated thyroid cancer (RR‐DTC)
Majid, Oneeb, Hayato, Seiichi, Sreerama Reddy, Sree Harsha, Lalovic, Bojan, Hihara, Taro, Hoshi, Taisuke, Funahashi, Yasuhiro, Aluri, Jagadeesh, Takenaka, Osamu, Yasuda, Sanae, Hussein, Ziad
Published in CPT: pharmacometrics and systems pharmacology (01.06.2024)
Published in CPT: pharmacometrics and systems pharmacology (01.06.2024)
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Journal Article
Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant
Landry, Ishani, Aluri, Jagadeesh, Hall, Nancy, Filippov, Gleb, Dayal, Satish, Moline, Margaret, Reyderman, Larisa
Published in Pharmacology research & perspectives (01.04.2021)
Published in Pharmacology research & perspectives (01.04.2021)
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Journal Article
Bioavailability of Three Rufinamide Oral Suspensions Compared With the Marketed 400-mg Tablet Formulation: Results From a Randomized-Sequence, Open-Label, Four-Period, Four-Sequence Crossover Study in Healthy Subjects
Critchley, David John, PhD, Aluri, Jagadeesh, MS, Boyd, Peter, MSc, Whayman, Matthew, MSc, Narurkar, Milind, PhD, Delargy, Hugh, PhD, Bibbiani, Francesco, MD
Published in Clinical therapeutics (2011)
Published in Clinical therapeutics (2011)
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Journal Article
Population Pharmacokinetics and Exposure‐Response Analyses for the Most Frequent Adverse Events Following Treatment With Lemborexant, an Orexin Receptor Antagonist, in Subjects With Insomnia Disorder
Lalovic, Bojan, Majid, Oneeb, Aluri, Jagadeesh, Landry, Ishani, Moline, Margaret, Hussein, Ziad
Published in Journal of clinical pharmacology (01.12.2020)
Published in Journal of clinical pharmacology (01.12.2020)
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Journal Article
Developing Topics
Zhou, Jin, Rawal, Sumit, Yagi, Takuya, Wildsmith, Kristin R, Takahashi, Eri, Horie, Kanta, Barthélemy, Nicolas R, Aluri, Jagadeesh, Lalovic, Bojan, Boyd, Peter, Bateman, Randall J, Reyderman, Larisa
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Pharmacokinetic/pharmacodynamic drug–drug interactions of avatrombopag when coadministered with dual or selective CYP2C9 and CYP3A interacting drugs
Nomoto, Maiko, Zamora, Cynthia A., Schuck, Edgar, Boyd, Peter, Chang, Min‐Kun, Aluri, Jagadeesh, Siu, Y. Amy, Lai, W. George, Yasuda, Sanae, Ferry, Jim, Rege, Bhaskar
Published in British journal of clinical pharmacology (01.05.2018)
Published in British journal of clinical pharmacology (01.05.2018)
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Journal Article
An Open-Label Phase 1 Study to Determine the Effect of Lenvatinib on the Pharmacokinetics of Midazolam, a CYP3A4 Substrate, in Patients with Advanced Solid Tumors
Shumaker, Robert, Ren, Min, Aluri, Jagadeesh, Dutcus, Corina E., Rance, Christian, He, Cixin
Published in European journal of drug metabolism and pharmacokinetics (01.06.2020)
Published in European journal of drug metabolism and pharmacokinetics (01.06.2020)
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Journal Article
Effects of Lemborexant on the Pharmacokinetics of Oral Contraceptives: Results From a Phase 1 Drug‐Drug Interaction Study in Healthy Females
Landry, Ishani, Aluri, Jagadeesh, Hall, Nancy, Filippov, Gleb, Dayal, Satish, Moline, Margaret, Reyderman, Larisa
Published in Clinical pharmacology in drug development (01.09.2021)
Published in Clinical pharmacology in drug development (01.09.2021)
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Journal Article
Evaluation of the CYP3A and CYP2B6 Drug‐Drug Interaction Potential of Lemborexant
Landry, Ishani, Aluri, Jagadeesh, Nakai, Kenya, Hall, Nancy, Miyajima, Yukiko, Ueno, Takashi, Dayal, Satish, Filippov, Gleb, Lalovic, Bojan, Moline, Margaret, Reyderman, Larisa
Published in Clinical pharmacology in drug development (01.06.2021)
Published in Clinical pharmacology in drug development (01.06.2021)
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Journal Article
Effect of lenvatinib (E7080) on the QTc interval: results from a thorough QT study in healthy volunteers
Shumaker, Robert C., Zhou, Meijian, Ren, Min, Fan, Jean, Martinez, Gresel, Aluri, Jagadeesh, Darpo, Borje
Published in Cancer chemotherapy and pharmacology (01.06.2014)
Published in Cancer chemotherapy and pharmacology (01.06.2014)
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Journal Article
A randomized, three-treatment, three-period, six-sequence-crossover, single-center, bioequivalence study to evaluate the impact of different 10-mg crystalline forms on the pharmacokinetics of lenvatinib in healthy volunteers
Lee, Lucy, D'Angelo, Pina, Verbel, David, Martinez, Gresel, Aluri, Jagadeesh, Brimhall, Darin
Published in International journal of clinical pharmacology and therapeutics (01.02.2015)
Published in International journal of clinical pharmacology and therapeutics (01.02.2015)
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Journal Article
Pharmacokinetics and pharmacodynamics of argatroban in combination with a platelet glycoprotein IIB/IIIA receptor antagonist in patients undergoing percutaneous coronary intervention
Cox, Donna S, Kleiman, Neal S, Boyle, Duane A, Aluri, Jagadeesh, Parchman, L Gerald, Holdbrook, Frederick, Fossler, Michael J
Published in Journal of clinical pharmacology (01.09.2004)
Published in Journal of clinical pharmacology (01.09.2004)
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