APOBEC3A catalyzes mutation and drives carcinogenesis in vivo
Law, Emily K, Levin-Klein, Rena, Jarvis, Matthew C, Kim, Hyoung, Argyris, Prokopios P, Carpenter, Michael A, Starrett, Gabriel J, Temiz, Nuri A, Larson, Lindsay K, Durfee, Cameron, Burns, Michael B, Vogel, Rachel I, Stavrou, Spyridon, Aguilera, Alexya N, Wagner, Sandra, Largaespada, David A, Starr, Timothy K, Ross, Susan R, Harris, Reuben S
Published in The Journal of experimental medicine (07.12.2020)
Published in The Journal of experimental medicine (07.12.2020)
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Journal Article
The DNA Cytosine Deaminase APOBEC3B is a Molecular Determinant of Platinum Responsiveness in Clear Cell Ovarian Cancer
Serebrenik, Artur A, Argyris, Prokopios P, Jarvis, Matthew C, Brown, William L, Bazzaro, Martina, Vogel, Rachel I, Erickson, Britt K, Lee, Sun-Hee, Goergen, Krista M, Maurer, Matthew J, Heinzen, Ethan P, Oberg, Ann L, Huang, Yajue, Hou, Xiaonan, Weroha, S John, Kaufmann, Scott H, Harris, Reuben S
Published in Clinical cancer research (01.07.2020)
Published in Clinical cancer research (01.07.2020)
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Journal Article
Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer
Carpenter, Michael A, Temiz, Nuri A, Ibrahim, Mahmoud A, Jarvis, Matthew C, Brown, Margaret R, Argyris, Prokopios P, Brown, William L, Starrett, Gabriel J, Yee, Douglas, Harris, Reuben S
Published in PLoS genetics (30.11.2023)
Published in PLoS genetics (30.11.2023)
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Characterization of the mechanism by which the RB/E2F pathway controls expression of the cancer genomic DNA deaminase APOBEC3B
Roelofs, Pieter A, Goh, Chai Yeen, Chua, Boon Haow, Jarvis, Matthew C, Stewart, Teneale A, McCann, Jennifer L, McDougle, Rebecca M, Carpenter, Michael A, Martens, John Wm, Span, Paul N, Kappei, Dennis, Harris, Reuben S
Published in eLife (28.09.2020)
Published in eLife (28.09.2020)
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Journal Article
The deaminase APOBEC3B triggers the death of cells lacking uracil DNA glycosylase
Serebrenik, Artur A., Starrett, Gabriel J., Leenen, Sterre, Jarvis, Matthew C., Shaban, Nadine M., Salamango, Daniel J., Nilsen, Hilde, Brown, William L., Harris, Reuben S.
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2019)
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APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer
McCann, Jennifer L., Cristini, Agnese, Law, Emily K., Lee, Seo Yun, Tellier, Michael, Carpenter, Michael A., Beghè, Chiara, Kim, Jae Jin, Sanchez, Anthony, Jarvis, Matthew C., Stefanovska, Bojana, Temiz, Nuri A., Bergstrom, Erik N., Salamango, Daniel J., Brown, Margaret R., Murphy, Shona, Alexandrov, Ludmil B., Miller, Kyle M., Gromak, Natalia, Harris, Reuben S.
Published in Nature genetics (01.10.2023)
Published in Nature genetics (01.10.2023)
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Primary mucosal melanomas of the head and neck are characterised by overexpression of the DNA mutating enzyme APOBEC3B
Argyris, Prokopios P, Naumann, Jordan, Jarvis, Matthew C, Wilkinson, Peter E, Ho, Dan P, Islam, Mohammed N, Bhattacharyya, Indraneel, Gopalakrishnan, Rajaram, Li, Faqian, Koutlas, Ioannis G, Giubellino, Alessio, Harris, Reuben S
Published in Histopathology (01.03.2023)
Published in Histopathology (01.03.2023)
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