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Mullarky, Edouard, Xu, Jiayi, Robin, Anita D., Huggins, David J., Jennings, Andy, Noguchi, Naoyoshi, Olland, Andrea, Lakshminarasimhan, Damodharan, Miller, Michael, Tomita, Daisuke, Michino, Mayako, Su, Taojunfeng, Zhang, Guoan, Stamford, Andrew W., Meinke, Peter T., Kargman, Stacia, Cantley, Lewis C.
Published in Bioorganic & medicinal chemistry letters (01.09.2019)
Published in Bioorganic & medicinal chemistry letters (01.09.2019)
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Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor
Cumming, Jared N., Smith, Elizabeth M., Wang, Lingyan, Misiaszek, Jeffrey, Durkin, James, Pan, Jianping, Iserloh, Ulrich, Wu, Yusheng, Zhu, Zhaoning, Strickland, Corey, Voigt, Johannes, Chen, Xia, Kennedy, Matthew E., Kuvelkar, Reshma, Hyde, Lynn A., Cox, Kathleen, Favreau, Leonard, Czarniecki, Michael F., Greenlee, William J., McKittrick, Brian A., Parker, Eric M., Stamford, Andrew W.
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
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A Novel Method for the Preparation of 4‑Arylimidazolones
DeMong, Duane E, Ng, Irene, Miller, Michael W, Stamford, Andrew W
Published in Organic letters (07.06.2013)
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On the power of super acid—iodination of aromatic ring in the presence of imidazole moiety of the potent gamma secretase modulators (GSM) en route to tritium labeling
Mandal, Mihirbaran, Lavey, Carolee, Buevich, Alexei V., Zhu, Zhaoning, Stamford, Andrew W., Liu, Xiaoxiang
Published in Tetrahedron letters (04.04.2012)
Published in Tetrahedron letters (04.04.2012)
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Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetes
Xia, Yan, Chackalamannil, Samuel, Greenlee, William J., Jayne, Charles, Neustadt, Bernard, Stamford, Andrew, Vaccaro, Henry, Xu, Xiaoying (Lucy), Baker, Hana, O’Neill, Kim, Woods, Morgan, Hawes, Brian, Kowalski, Tim
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
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Potent and selective adenosine A(2A) receptor antagonists: [1,2,4]-triazolo[4,3-c]pyrimidin-3-ones
Harris, Joel M, Neustadt, Bernard R, Zhang, Hongtao, Lachowicz, Jean, Cohen-Williams, Mary, Varty, Geoff, Hao, Jinsong, Stamford, Andrew W
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
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Combining NMR and X-ray crystallography in fragment-based drug discovery: discovery of highly potent and selective BACE-1 inhibitors
Wyss, Daniel F, Wang, Yu-Sen, Eaton, Hugh L, Strickland, Corey, Voigt, Johannes H, Zhu, Zhaoning, Stamford, Andrew W
Published in Topics in current chemistry (01.01.2012)
Published in Topics in current chemistry (01.01.2012)
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Tetrahydroquinoline sulfonamides as vasopressin 1b receptor anatgonists
Scott, Jack D., Miller, Michael W., Li, Sarah W., Lin, Sue-Ing, Vaccaro, Henry A., Hong, Liwu, Mullins, Deborra E., Guzzi, Mario, Weinstein, Jay, Hodgson, Robert A., Varty, Geoffrey B., Stamford, Andrew W., Chan, Tin-Yau, McKittrick, Brian A., Greenlee, William J., Priestley, Tony, Parker, Eric M.
Published in Bioorganic & medicinal chemistry letters (01.11.2009)
Published in Bioorganic & medicinal chemistry letters (01.11.2009)
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Diaryl piperidines as CB1 receptor antagonists
SCOTT, Jack D, LI, Sarah W, STAMFORD, Andrew W, CHACKALAMANNIL, Samuel, LACHOWICZ, Jean E, GREENLEE, William J, HONGWU WANG, YAN XIA, JAYNE, Charles L, MILLER, Michael W, DUFFY, Ruth A, BOYKOW, George C, KOWALSKI, Timothy J, SPAR, Brian D
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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Optimization of purine based PDE1/PDE5 inhibitors to a potent and selective PDE5 inhibitor for the treatment of male ED
Boyle, Craig D., Xu, Ruo, Asberom, Theodros, Chackalamannil, Samuel, Clader, John W., Greenlee, William J., Guzik, Henry, Hu, Yuequing, Hu, Zhiyong, Lankin, Claire M., Pissarnitski, Dmitri A., Stamford, Andrew W., Wang, Yuguang, Skell, Jeffrey, Kurowski, Stanley, Vemulapalli, Subbarao, Palamanda, Jairam, Chintala, Madhu, Wu, Ping, Myers, Joyce, Wang, Peng
Published in Bioorganic & medicinal chemistry letters (02.05.2005)
Published in Bioorganic & medicinal chemistry letters (02.05.2005)
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SAR development of polycyclic guanine derivatives targeted to the discovery of a selective PDE5 inhibitor for treatment of erectile dysfunction
PISSARNITSKI, Dmitri A, ASBEROM, Theodros, PALAMANDA, Jairam, STAMFORD, Andrew W, VEMULAPALLI, Subbarao, YUGUANG WANG, PENG WANG, PING WU, RUO XU, BOYLE, Craig D, CHACKALAMANNIL, Samuel, CHINTALA, Madhu, CLADER, John W, GREENLEE, William J, YUEQING HU, KUROWSKI, Stanley, MYERS, Joyce
Published in Bioorganic & medicinal chemistry letters (08.03.2004)
Published in Bioorganic & medicinal chemistry letters (08.03.2004)
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Design and synthesis of xanthine analogues as potent and selective PDE5 inhibitors
Wang, Yuguang, Chackalamannil, Samuel, Hu, Zhiyong, Boyle, Craig D, Lankin, Claire M, Xia, Yan, Xu, Ruo, Asberom, Theodros, Pissarnitski, Dmitri, Stamford, Andrew W, Greenlee, William J, Skell, Jeffrey, Kurowski, Stanley, Vemulapalli, Subbarao, Palamanda, Jairam, Chintala, Madhu, Wu, Ping, Myers, Joyce, Wang, Peng
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
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Nonoxidative coupling methodology for the synthesis of the antitumor bisindole alkaloid vinblastine and a lower-half analog: solvent effect on the stereochemistry of the crucial C-15/C-18' bond
Magnus, Philip, Mendoza, Jose S., Stamford, Andrew, Ladlow, Mark, Willis, Paul
Published in Journal of the American Chemical Society (01.12.1992)
Published in Journal of the American Chemical Society (01.12.1992)
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Unprecedented Reversal of Regioselectivity during Methanolysis and an Interception of Curtius Rearrangement
Mandal, Mihirbaran, Buevich, Alexei V., Wang, Hongwu, Brunskill, Andrew, Orth, Peter, Caldwell, John P., Liu, Xiaoxiang, Mazzola, Robert, Cumming, Jared, McKittrick, Brian, Zhu, Zhaoning, Stamford, Andrew
Published in European journal of organic chemistry (24.09.2021)
Published in European journal of organic chemistry (24.09.2021)
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Discovery of the oxazabicyclo[3.3.1]nonane derivatives as potent and orally active GPR119 agonists
Dai, Xing, Stamford, Andrew, Liu, Hong, Neustadt, Bernard, Hao, Jingsong, Kowalski, Tim, Hawes, Brian, Xu, Xiaoying, Baker, Hana, O’Neill, Kim, Woods, Morgan, Tang, Huadong, Greenlee, William
Published in Bioorganic & medicinal chemistry letters (15.11.2015)
Published in Bioorganic & medicinal chemistry letters (15.11.2015)
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Discovery of aminoquinazoline derivatives as human A(2A) adenosine receptor antagonists
Zhou, Gang, Aslanian, Robert, Gallo, Gioconda, Khan, Tanweer, Kuang, Rongze, Purakkattle, Biju, De Ruiz, Manuel, Stamford, Andrew, Ting, Pauline, Wu, Heping, Wang, Hongwu, Xiao, Dong, Yu, Tao, Zhang, Yonglian, Mullins, Deborra, Hodgson, Robert
Published in Bioorganic & medicinal chemistry letters (15.02.2016)
Published in Bioorganic & medicinal chemistry letters (15.02.2016)
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Year of Publication 23.09.2022
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Year of Publication 23.09.2022
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Use of molecular modeling aided design to dial out hERG liability in adenosine A(2A) receptor antagonists
Deng, Qiaolin, Lim, Yeon-Hee, Anand, Rajan, Yu, Younong, Kim, Jae-hun, Zhou, Wei, Zheng, Junying, Tempest, Paul, Levorse, Dorothy, Zhang, Xiaoping, Greene, Scott, Mullins, Deborra, Culberson, Chris, Sherborne, Brad, Parker, Eric M, Stamford, Andrew, Ali, Amjad
Published in Bioorganic & medicinal chemistry letters (01.08.2015)
Published in Bioorganic & medicinal chemistry letters (01.08.2015)
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Discovery of phenyl acetamides as potent and selective GPR119 agonists
Zhu, Cheng, Wang, Liping, Zhu, Yuping, Guo, Zack Zhiqiang, Liu, Ping, Hu, Zhiyong, Szewczyk, Jason W., Kang, Ling, Chicchi, Gary, Ehrhardt, Anka, Woods, Andrea, Seo, Toru, Woods, Morgan, van Heek, Margaret, Dingley, Karen H., Pang, Jianmei, Salituro, Gino M., Powell, Joyce, Terebetski, Jenna L., Hornak, Viktor, Campeau, Louis-Charles, Orr, Robert K., Ujjainwalla, Feroze, Miller, Michael, Stamford, Andrew, Wood, Harold B., Kowalski, Timothy, Nargund, Ravi P., Edmondson, Scott D.
Published in Bioorganic & medicinal chemistry letters (01.03.2017)
Published in Bioorganic & medicinal chemistry letters (01.03.2017)
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