ESI-IMS–MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules
Young, Lydia M., Saunders, Janet C., Mahood, Rachel A., Revill, Charlotte H., Foster, Richard J., Ashcroft, Alison E., Radford, Sheena E.
Published in Methods (San Diego, Calif.) (15.02.2016)
Published in Methods (San Diego, Calif.) (15.02.2016)
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Investigating the Structural Compaction of Biomolecules Upon Transition to the Gas-Phase Using ESI-TWIMS-MS
Devine, Paul W. A., Fisher, Henry C., Calabrese, Antonio N., Whelan, Fiona, Higazi, Daniel R., Potts, Jennifer R., Lowe, David C., Radford, Sheena E., Ashcroft, Alison E.
Published in Journal of the American Society for Mass Spectrometry (01.09.2017)
Published in Journal of the American Society for Mass Spectrometry (01.09.2017)
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Examination of Ataxin-3 (atx-3) Aggregation by Structural Mass Spectrometry Techniques: A Rationale for Expedited Aggregation upon Polyglutamine (polyQ) Expansion
Scarff, Charlotte A., Almeida, Bruno, Fraga, Joana, Macedo-Ribeiro, Sandra, Radford, Sheena E., Ashcroft, Alison E.
Published in Molecular & cellular proteomics (01.05.2015)
Published in Molecular & cellular proteomics (01.05.2015)
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Role of ADAMs in the Ectodomain Shedding and Conformational Conversion of the Prion Protein
Taylor, David R., Parkin, Edward T., Cocklin, Sarah L., Ault, James R., Ashcroft, Alison E., Turner, Anthony J., Hooper, Nigel M.
Published in The Journal of biological chemistry (21.08.2009)
Published in The Journal of biological chemistry (21.08.2009)
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Monitoring Copopulated Conformational States During Protein Folding Events Using Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry
Smith, David P., Giles, Kevin, Bateman, Robert H., Radford, Sheena E., Ashcroft, Alison E.
Published in Journal of the American Society for Mass Spectrometry (01.12.2007)
Published in Journal of the American Society for Mass Spectrometry (01.12.2007)
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Expanding the Repertoire of Amyloid Polymorphs by Co-polymerization of Related Protein Precursors
Sarell, Claire J., Woods, Lucy A., Su, Yongchao, Debelouchina, Galia T., Ashcroft, Alison E., Griffin, Robert G., Stockley, Peter G., Radford, Sheena E.
Published in The Journal of biological chemistry (08.03.2013)
Published in The Journal of biological chemistry (08.03.2013)
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The hepatitis B virus preS1 domain hijacks host trafficking proteins by motif mimicry
Jürgens, Maike C, Vörös, Judit, Rautureau, Gilles J P, Shepherd, Dale A, Pye, Valerie E, Muldoon, Jimmy, Johnson, Christopher M, Ashcroft, Alison E, Freund, Stefan M V, Ferguson, Neil
Published in Nature chemical biology (01.09.2013)
Published in Nature chemical biology (01.09.2013)
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Small molecule probes of protein aggregation
Young, Lydia M, Ashcroft, Alison E, Radford, Sheena E
Published in Current opinion in chemical biology (01.08.2017)
Published in Current opinion in chemical biology (01.08.2017)
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Mass spectrometric methods to analyze the structural organization of macromolecular complexes
Rajabi, Khadijeh, Ashcroft, Alison E., Radford, Sheena E.
Published in Methods (San Diego, Calif.) (01.11.2015)
Published in Methods (San Diego, Calif.) (01.11.2015)
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Mass Spectrometry Characterization of Higher Order Structural Changes Associated with the Fc-glycan Structure of the NISTmAb Reference Material, RM 8761
Groves, Kate, Cryar, Adam, Cowen, Simon, Ashcroft, Alison E, Quaglia, Milena
Published in Journal of the American Society for Mass Spectrometry (04.03.2020)
Published in Journal of the American Society for Mass Spectrometry (04.03.2020)
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N‐terminal acetylation of α‐synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer
Kang, Lijuan, Moriarty, Gina M., Woods, Lucy A., Ashcroft, Alison E., Radford, Sheena E., Baum, Jean
Published in Protein science (01.07.2012)
Published in Protein science (01.07.2012)
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Effects of Periplasmic Chaperones and Membrane Thickness on BamA-Catalyzed Outer-Membrane Protein Folding
Schiffrin, Bob, Calabrese, Antonio N., Higgins, Anna J., Humes, Julia R., Ashcroft, Alison E., Kalli, Antreas C., Brockwell, David J., Radford, Sheena E.
Published in Journal of molecular biology (24.11.2017)
Published in Journal of molecular biology (24.11.2017)
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An in vivo platform for identifying inhibitors of protein aggregation
Saunders, Janet C, Young, Lydia M, Mahood, Rachel A, Jackson, Matthew P, Revill, Charlotte H, Foster, Richard J, Smith, D Alastair, Ashcroft, Alison E, Brockwell, David J, Radford, Sheena E
Published in Nature chemical biology (01.02.2016)
Published in Nature chemical biology (01.02.2016)
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Mutational Analysis of the Ability of Resveratrol To Inhibit Amyloid Formation by Islet Amyloid Polypeptide: Critical Evaluation of the Importance of Aromatic–Inhibitor and Histidine–Inhibitor Interactions
Tu, Ling-Hsien, Young, Lydia M, Wong, Amy G, Ashcroft, Alison E, Radford, Sheena E, Raleigh, Daniel P
Published in Biochemistry (Easton) (27.01.2015)
Published in Biochemistry (Easton) (27.01.2015)
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Validation of ion mobility spectrometry - mass spectrometry as a screening tool to identify type II kinase inhibitors of FGFR1 kinase
Beeston, Helen S, Klein, Tobias, Norman, Richard A, Tucker, Julie A, Anderson, Malcolm, Ashcroft, Alison E, Holdgate, Geoffrey A
Published in Rapid communications in mass spectrometry (29.06.2021)
Published in Rapid communications in mass spectrometry (29.06.2021)
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