A perspective on mammalian upstream open reading frame function
Somers, Joanna, Pöyry, Tuija, Willis, Anne E.
Published in The international journal of biochemistry & cell biology (01.08.2013)
Published in The international journal of biochemistry & cell biology (01.08.2013)
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Cytosine-5 RNA methylation links protein synthesis to cell metabolism
Gkatza, Nikoletta A, Castro, Cecilia, Harvey, Robert F, Heiß, Matthias, Popis, Martyna C, Blanco, Sandra, Bornelöv, Susanne, Sajini, Abdulrahim A, Gleeson, Joseph G, Griffin, Julian L, West, James A, Kellner, Stefanie, Willis, Anne E, Dietmann, Sabine, Frye, Michaela
Published in PLoS biology (14.06.2019)
Published in PLoS biology (14.06.2019)
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The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER
Hall, Belinda S, Hill, Kirsti, McKenna, Michael, Ogbechi, Joy, High, Stephen, Willis, Anne E, Simmonds, Rachel E
Published in PLoS pathogens (01.04.2014)
Published in PLoS pathogens (01.04.2014)
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Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice
Moreno, Julie A, Halliday, Mark, Molloy, Colin, Radford, Helois, Verity, Nicholas, Axten, Jeffrey M, Ortori, Catharine A, Willis, Anne E, Fischer, Peter M, Barrett, David A, Mallucci, Giovanna R
Published in Science translational medicine (09.10.2013)
Published in Science translational medicine (09.10.2013)
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Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer
Delaunay, Sylvain, Rapino, Francesca, Tharun, Lars, Zhou, Zhaoli, Heukamp, Lukas, Termathe, Martin, Shostak, Kateryna, Klevernic, Iva, Florin, Alexandra, Desmecht, Hadrien, Desmet, Christophe J, Nguyen, Laurent, Leidel, Sebastian A, Willis, Anne E, Büttner, Reinhard, Chariot, Alain, Close, Pierre
Published in The Journal of experimental medicine (17.10.2016)
Published in The Journal of experimental medicine (17.10.2016)
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Sustained translational repression by eIF2α-P mediates prion neurodegeneration
Moreno, Julie A., Radford, Helois, Peretti, Diego, Steinert, Joern R., Verity, Nicholas, Martin, Maria Guerra, Halliday, Mark, Morgan, Jason, Dinsdale, David, Ortori, Catherine A., Barrett, David A., Tsaytler, Pavel, Bertolotti, Anne, Willis, Anne E., Bushell, Martin, Mallucci, Giovanna R.
Published in Nature (London) (24.05.2012)
Published in Nature (London) (24.05.2012)
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Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein
Sawicka, Kirsty, Bushell, Martin, Spriggs, Keith A, Willis, Anne E
Published in Biochemical Society transactions (01.08.2008)
Published in Biochemical Society transactions (01.08.2008)
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Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma
Falletta, Paola, Sanchez-Del-Campo, Luis, Chauhan, Jagat, Effern, Maike, Kenyon, Amy, Kershaw, Christopher J, Siddaway, Robert, Lisle, Richard, Freter, Rasmus, Daniels, Matthew J, Lu, Xin, Tüting, Thomas, Middleton, Mark, Buffa, Francesca M, Willis, Anne E, Pavitt, Graham, Ronai, Ze'ev A, Sauka-Spengler, Tatjana, Hölzel, Michael, Goding, Colin R
Published in Genes & development (01.01.2017)
Published in Genes & development (01.01.2017)
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Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response
Snieckute, Goda, Genzor, Aitana Victoria, Vind, Anna Constance, Ryder, Laura, Stoneley, Mark, Chamois, Sébastien, Dreos, René, Nordgaard, Cathrine, Sass, Frederike, Blasius, Melanie, López, Aida Rodríguez, Brynjólfsdóttir, Sólveig Hlín, Andersen, Kasper Langebjerg, Willis, Anne E., Frankel, Lisa B., Poulsen, Steen Seier, Gatfield, David, Gerhart-Hines, Zachary, Clemmensen, Christoffer, Bekker-Jensen, Simon
Published in Cell metabolism (06.12.2022)
Published in Cell metabolism (06.12.2022)
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RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration
Peretti, Diego, Bastide, Amandine, Radford, Helois, Verity, Nicholas, Molloy, Colin, Martin, Maria Guerra, Moreno, Julie A., Steinert, Joern R., Smith, Tim, Dinsdale, David, Willis, Anne E., Mallucci, Giovanna R.
Published in Nature (London) (12.02.2015)
Published in Nature (London) (12.02.2015)
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Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf)
Chernova, Tatyana, Murphy, Fiona A., Galavotti, Sara, Sun, Xiao-Ming, Powley, Ian R., Grosso, Stefano, Schinwald, Anja, Zacarias-Cabeza, Joaquin, Dudek, Kate M., Dinsdale, David, Le Quesne, John, Bennett, Jonathan, Nakas, Apostolos, Greaves, Peter, Poland, Craig A., Donaldson, Ken, Bushell, Martin, Willis, Anne E., MacFarlane, Marion
Published in Current biology (06.11.2017)
Published in Current biology (06.11.2017)
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Suboptimal T-cell receptor signaling compromises protein translation, ribosome biogenesis, and proliferation of mouse CD8 T cells
Tan, Thomas C. J., Knight, John, Sbarrato, Thomas, Dudek, Kate, Willis, Anne E., Zamoyska, Rose
Published in Proceedings of the National Academy of Sciences - PNAS (25.07.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (25.07.2017)
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mTORC1-mediated translational elongation limits intestinal tumour initiation and growth
Faller, William J., Jackson, Thomas J., Knight, John R. P., Ridgway, Rachel A., Jamieson, Thomas, Karim, Saadia A., Jones, Carolyn, Radulescu, Sorina, Huels, David J., Myant, Kevin B., Dudek, Kate M., Casey, Helen A., Scopelliti, Alessandro, Cordero, Julia B., Vidal, Marcos, Pende, Mario, Ryazanov, Alexey G., Sonenberg, Nahum, Meyuhas, Oded, Hall, Michael N., Bushell, Martin, Willis, Anne E., Sansom, Owen J.
Published in Nature (London) (22.01.2015)
Published in Nature (London) (22.01.2015)
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Journal Article
Control of translation elongation in health and disease
Knight, John R P, Garland, Gavin, Pöyry, Tuija, Mead, Emma, Vlahov, Nikola, Sfakianos, Aristeidis, Grosso, Stefano, De-Lima-Hedayioglu, Fabio, Mallucci, Giovanna R, von der Haar, Tobias, Smales, C Mark, Sansom, Owen J, Willis, Anne E
Published in Disease models & mechanisms (26.03.2020)
Published in Disease models & mechanisms (26.03.2020)
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Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4
Ogbechi, Joy, Hall, Belinda S., Sbarrato, Thomas, Taunton, Jack, Willis, Anne E., Wek, Ronald C., Simmonds, Rachel E.
Published in Cell death & disease (14.03.2018)
Published in Cell death & disease (14.03.2018)
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Journal Article
Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease
Tufi, Roberta, Gandhi, Sonia, de Castro, Inês P., Lehmann, Susann, Angelova, Plamena R., Dinsdale, David, Deas, Emma, Plun-Favreau, Hélène, Nicotera, Pierluigi, Abramov, Andrey Y., Willis, Anne E., Mallucci, Giovanna R., Loh, Samantha H. Y., Martins, L. Miguel
Published in Nature cell biology (01.02.2014)
Published in Nature cell biology (01.02.2014)
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