Mitochondrial dysfunction and longevity in animals: Untangling the knot
Wang, Ying, Hekimi, Siegfried
Published in Science (American Association for the Advancement of Science) (04.12.2015)
Published in Science (American Association for the Advancement of Science) (04.12.2015)
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Journal Article
Superoxide dismutase is dispensable for normal animal lifespan
Van Raamsdonk, Jeremy Michael, Hekimi, Siegfried
Published in Proceedings of the National Academy of Sciences - PNAS (10.04.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (10.04.2012)
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Journal Article
Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging
Ben‐Meir, Assaf, Burstein, Eliezer, Borrego‐Alvarez, Aluet, Chong, Jasmine, Wong, Ellen, Yavorska, Tetyana, Naranian, Taline, Chi, Maggie, Wang, Ying, Bentov, Yaakov, Alexis, Jennifer, Meriano, James, Sung, Hoon‐Ki, Gasser, David L., Moley, Kelle H., Hekimi, Siegfried, Casper, Robert F., Jurisicova, Andrea
Published in Aging cell (01.10.2015)
Published in Aging cell (01.10.2015)
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Journal Article
Molecular genetics of ubiquinone biosynthesis in animals
Wang, Ying, Hekimi, Siegfried
Published in Critical reviews in biochemistry and molecular biology (01.01.2013)
Published in Critical reviews in biochemistry and molecular biology (01.01.2013)
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Journal Article
FUdR causes a twofold increase in the lifespan of the mitochondrial mutant gas-1
Van Raamsdonk, Jeremy Michael, Hekimi, Siegfried
Published in Mechanisms of ageing and development (01.10.2011)
Published in Mechanisms of ageing and development (01.10.2011)
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Journal Article
Genetics and the Specificity of the Aging Process
Hekimi, Siegfried, Guarente, Leonard
Published in Science (American Association for the Advancement of Science) (28.02.2003)
Published in Science (American Association for the Advancement of Science) (28.02.2003)
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Journal Article
Mitochondrial and cytoplasmic ROS have opposing effects on lifespan
Schaar, Claire E, Dues, Dylan J, Spielbauer, Katie K, Machiela, Emily, Cooper, Jason F, Senchuk, Megan, Hekimi, Siegfried, Van Raamsdonk, Jeremy M
Published in PLoS genetics (01.02.2015)
Published in PLoS genetics (01.02.2015)
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Journal Article
ROS regulation of RAS and vulva development in Caenorhabditis elegans
Kramer-Drauberg, Maximilian, Liu, Ju-Ling, Desjardins, David, Wang, Ying, Branicky, Robyn, Hekimi, Siegfried
Published in PLoS genetics (16.06.2020)
Published in PLoS genetics (16.06.2020)
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Journal Article
Antioxidants reveal an inverted U‐shaped dose‐response relationship between reactive oxygen species levels and the rate of aging in Caenorhabditis elegans
Desjardins, David, Cacho‐Valadez, Briseida, Liu, Ju‐Ling, Wang, Ying, Yee, Callista, Bernard, Kristine, Khaki, Arman, Breton, Lionel, Hekimi, Siegfried
Published in Aging cell (01.02.2017)
Published in Aging cell (01.02.2017)
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Journal Article
The submitochondrial distribution of ubiquinone affects respiration in long-lived Mclk1+/- mice
Lapointe, Jérôme, Wang, Ying, Bigras, Eve, Hekimi, Siegfried
Published in The Journal of cell biology (15.10.2012)
Published in The Journal of cell biology (15.10.2012)
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Journal Article
Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice
Liu, Xingxing, Jiang, Ning, Hughes, Bryan, Bigras, Eve, Shoubridge, Eric, Hekimi, Siegfried
Published in Genes & development (15.10.2005)
Published in Genes & development (15.10.2005)
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Journal Article
SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans
Krabbendam, Inge E., Honrath, Birgit, Dilberger, Benjamin, Iannetti, Eligio F., Branicky, Robyn S., Meyer, Tammo, Evers, Bernard, Dekker, Frank J., Koopman, Werner J. H., Beyrath, Julien, Bano, Daniele, Schmidt, Martina, Bakker, Barbara M., Hekimi, Siegfried, Culmsee, Carsten, Eckert, Gunter P., Dolga, Amalia M.
Published in Cell death & disease (23.04.2020)
Published in Cell death & disease (23.04.2020)
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