MA-[D-Leu-4]-OB3, a small molecule synthetic peptide leptin mimetic, improves episodic memory, and reduces serum levels of tumor necrosis factor-alpha and neurodegeneration in mouse models of Type 1 and Type 2 Diabetes Mellitus
Hirschstein, Zall, Vanga, Gautam Reddy, Wang, Guirong, Novakovic, Zachary M., Grasso, Patricia
Published in Biochimica et biophysica acta. General subjects (01.11.2020)
Published in Biochimica et biophysica acta. General subjects (01.11.2020)
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[D-Leu-4]-OB3 and MA-[D-Leu-4]-OB3, small molecule synthetic peptide leptin mimetics, improve glycemic control in diet-induced obese (DIO) mice
Wang, Anke, Anderson, Brian M., Novakovic, Zachary M., Grasso, Patricia
Published in Peptides (New York, N.Y. : 1980) (01.03.2018)
Published in Peptides (New York, N.Y. : 1980) (01.03.2018)
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Myristic acid conjugation of [D-Leu-4]-OB3, a biologically active leptin-related synthetic peptide amide, significantly improves its pharmacokinetic profile and efficacy
Novakovic, Zachary M., Anderson, Brian M., Grasso, Patricia
Published in Peptides (New York, N.Y. : 1980) (01.12.2014)
Published in Peptides (New York, N.Y. : 1980) (01.12.2014)
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[D-Leu-4]-OB3, an orally bioavailable leptin-related synthetic peptide insulin sensitizer: A study comparing the efficacies of [D-Leu-4]-OB3 and metformin on energy balance and glycemic regulation in insulin-deficient male Swiss Webster mice
Novakovic, Zachary M., Leinung, Matthew C., Grasso, Patricia
Published in Peptides (New York, N.Y. : 1980) (01.05.2013)
Published in Peptides (New York, N.Y. : 1980) (01.05.2013)
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Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin
Yang, Yu-Chen Sh, Chin, Yu-Tang, Hsieh, Meng-Ti, Lai, Hsuan-Yu, Ke, Chien-Chih, Crawford, Dana R, Lee, Oscar K, Fu, Earl, Mousa, Shaker A, Grasso, Patricia, Liu, Leroy F, Chang, Heng-Yu, Tang, Heng-Yuan, Lin, Hung-Yun, Davis, Paul J
Published in Oncotarget (10.05.2016)
Published in Oncotarget (10.05.2016)
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Intranasal administration of mouse [D-Leu-4]OB3, a synthetic peptide amide with leptin-like activity, enhances total uptake and bioavailability in Swiss Webster mice when compared to intraperitoneal, subcutaneous, and intramuscular delivery systems
Novakovic, Zachary M., Leinung, Matthew C., Lee, Daniel W., Grasso, Patricia
Published in Regulatory peptides (10.04.2009)
Published in Regulatory peptides (10.04.2009)
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Design of a synthetic leptin agonist: effects on energy balance, glucose homeostasis, and thermoregulation
Rozhavskaya-Arena, M, Lee, D W, Leinung, M C, Grasso, P
Published in Endocrinology (Philadelphia) (01.07.2000)
Published in Endocrinology (Philadelphia) (01.07.2000)
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Leptin and the treatment of obesity: its current status
Lee, Daniel W, Leinung, Matthew C, Rozhavskaya-Arena, Marina, Grasso, Patricia
Published in European journal of pharmacology (12.04.2002)
Published in European journal of pharmacology (12.04.2002)
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Inhibitory effects of leptin-related synthetic peptide 116-130 on food intake and body weight gain in female C57BL/6J ob/ob mice may not be mediated by peptide activation of the long isoform of the leptin receptor
GRASSO, P, WHITE, D. W, TARTAGLIA, L. A, LEINUNG, M. C, LEE, D. W
Published in Diabetes (New York, N.Y.) (01.11.1999)
Published in Diabetes (New York, N.Y.) (01.11.1999)
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