sharp T-cell antigen receptor signaling threshold for T-cell proliferation
Au-Yeung, Byron B, Zikherman, Julie, Mueller, James L, Ashouri, Judith F, Matloubian, Mehrdad, Cheng, Debra A, Chen, Yiling, Shokat, Kevan M, Weiss, Arthur
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2014)
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structure, regulation, and function of ZAP-70
Au-Yeung, Byron B, Deindl, Sebastian, Hsu, Lih-Yun, Palacios, Emil H, Levin, Susan E, Kuriyan, John, Weiss, Arthur
Published in Immunological reviews (01.03.2009)
Published in Immunological reviews (01.03.2009)
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Extrathymic Aire-Expressing Cells Are a Distinct Bone Marrow-Derived Population that Induce Functional Inactivation of CD4+ T Cells
Gardner, James M., Metzger, Todd C., McMahon, Eileen J., Au-Yeung, Byron B., Krawisz, Anna K., Lu, Wen, Price, Jeffrey D., Johannes, Kellsey P., Satpathy, Ansuman T., Murphy, Kenneth M., Tarbell, Kristin V., Weiss, Arthur, Anderson, Mark S.
Published in Immunity (Cambridge, Mass.) (19.09.2013)
Published in Immunity (Cambridge, Mass.) (19.09.2013)
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Distinct phases in the positive selection of CD8⁺ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns
Ross, Jenny O., Melichar, Heather J., Au-Yeung, Byron B., Herzmark, Paul, Weiss, Arthur, Robey, Ellen A.
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2014)
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Reduced interferon‐α production by dendritic cells in type 1 diabetes does not impair immunity to influenza virus
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Published in Clinical and experimental immunology (01.02.2015)
Published in Clinical and experimental immunology (01.02.2015)
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Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation
Phee, Hyewon, Au-Yeung, Byron B, Pryshchep, Olga, O'Hagan, Kyle Leonard, Fairbairn, Stephanie Grace, Radu, Maria, Kosoff, Rachelle, Mollenauer, Marianne, Cheng, Debra, Chernoff, Jonathan, Weiss, Arthur
Published in eLife (13.05.2014)
Published in eLife (13.05.2014)
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Anti‐atherogenic peptide Ep1.B derived from apolipoprotein E induces tolerogenic plasmacytoid dendritic cells
Bellemore, S. M., Nikoopour, E., Au, B. C. Y., Krougly, O., Lee‐Chan, E., Haeryfar, S. M., Singh, B.
Published in Clinical and experimental immunology (01.09.2014)
Published in Clinical and experimental immunology (01.09.2014)
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Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes
Scaife, M, Pacienza, N, Au, B C Y, Wang, J C M, Devine, S, Scheid, E, Lee, C-J, Lopez-Perez, O, Neschadim, A, Fowler, D H, Foley, R, Medin, J A
Published in Gene therapy (01.01.2013)
Published in Gene therapy (01.01.2013)
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ZAP-70: an essential kinase in T-cell signaling
Wang, Haopeng, Kadlecek, Theresa A, Au-Yeung, Byron B, Goodfellow, Hanna E Sjölin, Hsu, Lih-Yun, Freedman, Tanya S, Weiss, Arthur
Published in Cold Spring Harbor perspectives in biology (01.05.2010)
Published in Cold Spring Harbor perspectives in biology (01.05.2010)
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Dominant-negative NFKBIA mutation promotes IL-1β production causing hepatic disease with severe immunodeficiency
Tan, Enrica Ek, Hopkins, Richard A, Lim, Chrissie K, Jamuar, Saumya S, Ong, Christina, Thoon, Koh C, Koh, Mark Ja, Shin, Eun Mong, Lian, Derrick Wq, Weerasooriya, Madhushanee, Lee, Christopher Zw, Soetedjo, Andreas Alvin Pumomo, Lim, Chang Siang, Au, Veonice B, Chua, Edmond, Lee, Hui Yin, Jones, Leigh Ann, James, Sharmy S, Kaliaperumal, Nivashini, Kwok, Jeffery, Tan, Ee Shien, Thomas, Biju, Wu, Lynn Xue, Ho, Lena, Fairhurst, Anna Marie, Ginhoux, Florent, Teo, Adrian Kk, Zhang, Yong Liang, Ong, Kok Huar, Yu, Weimiao, Venkatesh, Byrappa, Tergaonkar, Vinay, Reversade, Bruno, Chin, Keh Chuang, Tan, Ah Moy, Liew, Woei Kang, Connolly, John E
Published in The Journal of clinical investigation (02.11.2020)
Published in The Journal of clinical investigation (02.11.2020)
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IL-2 Modulates the TCR Signaling Threshold for CD8 but Not CD4 T Cell Proliferation on a Single-Cell Level
Au-Yeung, Byron B, Smith, Geoffrey Alexander, Mueller, James L, Heyn, Cheryl S, Jaszczak, Rebecca Garrett, Weiss, Arthur, Zikherman, Julie
Published in The Journal of immunology (1950) (15.03.2017)
Published in The Journal of immunology (1950) (15.03.2017)
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The phosphatidylinositol-transfer protein Nir3 promotes PI(4,5)P 2 replenishment in response to TCR signaling during T cell development and survival
Lu, Wen, Helou, Ynes A, Shrinivas, Krishna, Liou, Jen, Au-Yeung, Byron B, Weiss, Arthur
Published in Nature immunology (01.01.2023)
Published in Nature immunology (01.01.2023)
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Cbl-b mitigates the responsiveness of naive CD8 + T cells that experience extensive tonic T cell receptor signaling
Eggert, Joel, Zinzow-Kramer, Wendy M, Hu, Yuesong, Kolawole, Elizabeth M, Tsai, Yuan-Li, Weiss, Arthur, Evavold, Brian D, Salaita, Khalid, Scharer, Christopher D, Au-Yeung, Byron B
Published in Science signaling (06.02.2024)
Published in Science signaling (06.02.2024)
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A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity
Cheng, Debra A, Hsu, Lih-Yun, Shokat, Kevan M, Zhang, Chao, Au-Yeung, Byron B, Killeen, Nigel, Levin, Susan E, Weiss, Arthur
Published in Nature immunology (01.12.2010)
Published in Nature immunology (01.12.2010)
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Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development
Au-Yeung, Byron B, Melichar, Heather J, Ross, Jenny O, Cheng, Debra A, Zikherman, Julie, Shokat, Kevan M, Robey, Ellen A, Weiss, Arthur
Published in Nature immunology (01.07.2014)
Published in Nature immunology (01.07.2014)
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