A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models
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Published in Aging cell (01.02.2020)
Published in Aging cell (01.02.2020)
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Autophagy deficiency in neurodevelopmental disorders
Deng, Zhiqiang, Zhou, Xiaoting, Lu, Jia-Hong, Yue, Zhenyu
Published in Cell & bioscience (17.12.2021)
Published in Cell & bioscience (17.12.2021)
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Natural Alkaloid Compounds as Inhibitors for Alpha-Synuclein Seeded Fibril Formation and Toxicity
Ghanem, Simona S., Fayed, Hend S., Zhu, Qi, Lu, Jia-Hong, Vaikath, Nishant N., Ponraj, Janarthanan, Mansour, Said, El-Agnaf, Omar M. A.
Published in Molecules (Basel, Switzerland) (19.06.2021)
Published in Molecules (Basel, Switzerland) (19.06.2021)
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Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice
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Published in Molecular neurodegeneration (27.11.2019)
Published in Molecular neurodegeneration (27.11.2019)
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Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow
Xie, Chenglong, Zhuang, Xu-Xu, Niu, Zhangming, Ai, Ruixue, Lautrup, Sofie, Zheng, Shuangjia, Jiang, Yinghui, Han, Ruiyu, Gupta, Tanima Sen, Cao, Shuqin, Lagartos-Donate, Maria Jose, Cai, Cui-Zan, Xie, Li-Ming, Caponio, Domenica, Wang, Wen-Wen, Schmauck-Medina, Tomas, Zhang, Jianying, Wang, He-ling, Lou, Guofeng, Xiao, Xianglu, Zheng, Wenhua, Palikaras, Konstantinos, Yang, Guang, Caldwell, Kim A., Caldwell, Guy A., Shen, Han-Ming, Nilsen, Hilde, Lu, Jia-Hong, Fang, Evandro F.
Published in Nature biomedical engineering (01.01.2022)
Published in Nature biomedical engineering (01.01.2022)
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Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling
Chong, Cheong-Meng, Ke, Minjing, Tan, Yuan, Huang, Zhijian, Zhang, Ke, Ai, Nana, Ge, Wei, Qin, Dajiang, Lu, Jia-Hong, Su, Huanxing
Published in Cell death & disease (29.08.2018)
Published in Cell death & disease (29.08.2018)
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Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models
Iyaswamy, Ashok, Wang, Xueli, Krishnamoorthi, Senthilkumar, Kaliamoorthy, Venkatapathy, Sreenivasmurthy, Sravan G., Kumar Durairajan, Siva Sundara, Song, Ju-Xian, Tong, Benjamin Chun-kit, Zhu, Zhou, Su, Cheng-Fu, Liu, Jia, Cheung, King-Ho, Lu, Jia-Hong, Tan, Jie-Qiong, Li, Hung Wing, Wong, Man Shing, Li, Min
Published in Redox biology (01.05.2022)
Published in Redox biology (01.05.2022)
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Targeting ATG4 in Cancer Therapy
Fu, Yuanyuan, Huang, Zhiying, Hong, Liang, Lu, Jia-Hong, Feng, Du, Yin, Xiao-Ming, Li, Min
Published in Cancers (10.05.2019)
Published in Cancers (10.05.2019)
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Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles
Deng, Zhiqiang, Dong, Yu, Zhou, Xiaoting, Lu, Jia-Hong, Yue, Zhenyu
Published in Acta pharmaceutica Sinica. B (01.04.2022)
Published in Acta pharmaceutica Sinica. B (01.04.2022)
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Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models
Cai, Cui-Zan, Zhuang, Xu-Xu, Zhu, Qi, Wu, Ming-Yue, Su, Huanxing, Wang, Xiao-Jin, Iyaswamy, Ashok, Yue, Zhenyu, Wang, Qian, Zhang, Bin, Xue, Yu, Tan, Jieqiong, Li, Min, He, Huanhuan, Lu, Jia-Hong
Published in Theranostics (2022)
Published in Theranostics (2022)
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TRPV1 Modulator Ameliorates Alzheimer-Like Amyloid-β Neuropathology via Akt/Gsk3β-Mediated Nrf2 Activation in the Neuro-2a/APP Cell Model
Wang, Xiufen, Bian, Yaqi, Wong, Clarence Tsun Ting, Lu, Jia-Hong, Lee, Simon Ming-Yuen
Published in Oxidative medicine and cellular longevity (2022)
Published in Oxidative medicine and cellular longevity (2022)
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Presenilin-1 F105C mutation leads to tau accumulation in human neurons via the Akt/mTORC1 signaling pathway
Chong, Cheong-Meng, Tan, Yuan, Tong, Jiaqi, Ke, Minjing, Zhang, Ke, Yan, Lingli, Cen, Xiaotong, Lu, Jia-Hong, Chen, Guobing, Su, Huanxing, Qin, Dajiang
Published in Cell & bioscience (14.08.2022)
Published in Cell & bioscience (14.08.2022)
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Fish oil protects the blood-brain barrier integrity in a mouse model of Alzheimer's disease
Xie, Youna, Yan, Lingli, Zeng, Haitao, Chen, Weineng, Lu, Jia-Hong, Wan, Jian-Bo, Su, Huanxing, Yao, Xiaoli
Published in Chinese medicine (30.03.2020)
Published in Chinese medicine (30.03.2020)
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NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models
Iyaswamy, Ashok, Krishnamoorthi, Senthil Kumar, Song, Ju-Xian, Yang, Chuan-Bin, Kaliyamoorthy, Venkatapathy, Zhang, Huan, Sreenivasmurthy, Sravan G., Malampati, Sandeep, Wang, Zi-Ying, Zhu, Zhou, Tong, Benjamin Chun-Kit, Cheung, King-Ho, Lu, Jia-Hong, Durairajan, Siva Sundara Kumar, Li, Min
Published in Yàowu shi͡p︡in fenxi (01.01.2020)
Published in Yàowu shi͡p︡in fenxi (01.01.2020)
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Neuroprotective effects of berberine in animal models of Alzheimer's disease: a systematic review of pre-clinical studies
Yuan, Ning-Ning, Cai, Cui-Zan, Wu, Ming-Yue, Su, Huan-Xing, Li, Min, Lu, Jia-Hong
Published in BMC complementary and alternative medicine (23.05.2019)
Published in BMC complementary and alternative medicine (23.05.2019)
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