Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes
Li, Jiwen, Pan, Lin, Pembroke, William G., Rexach, Jessica E., Godoy, Marlesa I., Condro, Michael C., Alvarado, Alvaro G., Harteni, Mineli, Chen, Yen-Wei, Stiles, Linsey, Chen, Angela Y., Wanner, Ina B., Yang, Xia, Goldman, Steven A., Geschwind, Daniel H., Kornblum, Harley I., Zhang, Ye
Published in Nature communications (25.06.2021)
Published in Nature communications (25.06.2021)
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Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
Bi, Junfeng, Ichu, Taka-Aki, Zanca, Ciro, Yang, Huijun, Zhang, Wei, Gu, Yuchao, Chowdhry, Sudhir, Reed, Alex, Ikegami, Shiro, Turner, Kristen M., Zhang, Wenjing, Villa, Genaro R., Wu, Sihan, Quehenberger, Oswald, Yong, William H., Kornblum, Harley I., Rich, Jeremy N., Cloughesy, Timothy F., Cavenee, Webster K., Furnari, Frank B., Cravatt, Benjamin F., Mischel, Paul S.
Published in Cell metabolism (03.09.2019)
Published in Cell metabolism (03.09.2019)
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Flow-Mediated Susceptibility and Molecular Response of Cerebral Endothelia to SARS-CoV-2 Infection
Kaneko, Naoki, Satta, Sandro, Komuro, Yutaro, Muthukrishnan, Sree Deepthi, Kakarla, Visesha, Guo, Lea, An, Jennifer, Elahi, Fanny, Kornblum, Harley I, Liebeskind, David S, Hsiai, Tzung, Hinman, Jason D
Published in Stroke (1970) (01.01.2021)
Published in Stroke (1970) (01.01.2021)
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Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA
Nathanson, David A., Gini, Beatrice, Mottahedeh, Jack, Visnyei, Koppany, Koga, Tomoyuki, Gomez, German, Estin, Ascia, Hwang, Kiwook, Wang, Jun, Masui, Kenta, Paucar, Andres, Yang, Huijun, Ohashi, Minori, Zhu, Shaojun, Wykosky, Jill, Reed, Rachel, Nelson, Stanley F., Cloughesy, Timothy F., James, C. David, Rao, P. Nagesh, Kornblum, Harley I., Heath, James R., Cavenee, Webster K., Furnari, Frank B., Mischel, Paul S.
Published in Science (American Association for the Advancement of Science) (03.01.2014)
Published in Science (American Association for the Advancement of Science) (03.01.2014)
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Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity
Turner, Kristen M., Deshpande, Viraj, Beyter, Doruk, Koga, Tomoyuki, Rusert, Jessica, Lee, Catherine, Li, Bin, Arden, Karen, Ren, Bing, Nathanson, David A., Kornblum, Harley I., Taylor, Michael D., Kaushal, Sharmeela, Cavenee, Webster K., Wechsler-Reya, Robert, Furnari, Frank B., Vandenberg, Scott R., Rao, P. Nagesh, Wahl, Geoffrey M., Bafna, Vineet, Mischel, Paul S.
Published in Nature (London) (02.03.2017)
Published in Nature (London) (02.03.2017)
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Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro
Lewerenz, Jan, Albrecht, Philipp, Tien, Mai-Ly Tran, Henke, Nadine, Karumbayaram, Saravanan, Kornblum, Harley I, Wiedau-Pazos, Martina, Schubert, Dave, Maher, Pamela, Methner, Axel
Published in Journal of neurochemistry (01.10.2009)
Published in Journal of neurochemistry (01.10.2009)
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Journal Article
MELK‐Dependent FOXM1 Phosphorylation is Essential for Proliferation of Glioma Stem Cells
Joshi, Kaushal, Banasavadi‐Siddegowda, Yeshavanth, Mo, Xiaokui, Kim, Sung‐Hak, Mao, Ping, Kig, Cenk, Nardini, Diana, Sobol, Robert W., Chow, Lionel M.L., Kornblum, Harley I., Waclaw, Ronald, Beullens, Monique, Nakano, Ichiro
Published in Stem cells (Dayton, Ohio) (01.06.2013)
Published in Stem cells (Dayton, Ohio) (01.06.2013)
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Journal Article
Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2
Wang, Jia, Cheng, Peng, Pavlyukov, Marat S, Yu, Hai, Zhang, Zhuo, Kim, Sung-Hak, Minata, Mutsuko, Mohyeldin, Ahmed, Xie, Wanfu, Chen, Dongquan, Goidts, Violaine, Frett, Brendan, Hu, Wenhao, Li, Hongyu, Shin, Yong Jae, Lee, Yeri, Nam, Do-Hyun, Kornblum, Harley I, Wang, Maode, Nakano, Ichiro
Published in The Journal of clinical investigation (01.08.2017)
Published in The Journal of clinical investigation (01.08.2017)
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Distinct Tlr4-expressing cell compartments control neutrophilic and eosinophilic airway inflammation
McAlees, J W, Whitehead, G S, Harley, I TW, Cappelletti, M, Rewerts, C L, Holdcroft, A M, Divanovic, S, Wills-Karp, M, Finkelman, F D, Karp, C L, Cook, D N
Published in Mucosal immunology (01.07.2015)
Published in Mucosal immunology (01.07.2015)
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Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner
Le Belle, Janel E., Orozco, Nicolas M., Paucar, Andres A., Saxe, Jonathan P., Mottahedeh, Jack, Pyle, April D., Wu, Hong, Kornblum, Harley I.
Published in Cell stem cell (07.01.2011)
Published in Cell stem cell (07.01.2011)
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CD44v6 regulates growth of brain tumor stem cells partially through the AKT-mediated pathway
Jijiwa, Mayumi, Demir, Habibe, Gupta, Snehalata, Leung, Crystal, Joshi, Kaushal, Orozco, Nicholas, Huang, Tiffany, Yildiz, Vedat O, Shibahara, Ichiyo, de Jesus, Jason A, Yong, William H, Mischel, Paul S, Fernandez, Soledad, Kornblum, Harley I, Nakano, Ichiro
Published in PloS one (06.09.2011)
Published in PloS one (06.09.2011)
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Journal Article
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug
Bi, Junfeng, Khan, Atif, Tang, Jun, Armando, Aaron M., Wu, Sihan, Zhang, Wei, Gimple, Ryan C., Reed, Alex, Jing, Hui, Koga, Tomoyuki, Wong, Ivy Tsz-Lo, Gu, Yuchao, Miki, Shunichiro, Yang, Huijun, Prager, Briana, Curtis, Ellis J., Wainwright, Derek A., Furnari, Frank B., Rich, Jeremy N., Cloughesy, Timothy F., Kornblum, Harley I., Quehenberger, Oswald, Rzhetsky, Andrey, Cravatt, Benjamin F., Mischel, Paul S.
Published in Cell reports (Cambridge) (02.11.2021)
Published in Cell reports (Cambridge) (02.11.2021)
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Nicotinamide Adenine Dinucleotide Phosphate Oxidase Promotes Glioblastoma Radiation Resistance in a Phosphate and Tensin Homolog-Dependent Manner
Ludwig, Kirsten, Le Belle, Janel E, Muthukrishnan, Sree Deepthi, Sperry, Jantzen, Condro, Michael, Vlashi, Erina, Pajonk, Frank, Kornblum, Harley I
Published in Antioxidants & redox signaling (01.11.2023)
Published in Antioxidants & redox signaling (01.11.2023)
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Neural Stem Cells (NSCs) and Proteomics
Shoemaker, Lorelei D., Kornblum, Harley I.
Published in Molecular & cellular proteomics (01.02.2016)
Published in Molecular & cellular proteomics (01.02.2016)
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Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy
Pope, Whitney B., Prins, Robert M., Albert Thomas, M., Nagarajan, Rajakumar, Yen, Katharine E., Bittinger, Mark A., Salamon, Noriko, Chou, Arthur P., Yong, William H., Soto, Horacio, Wilson, Neil, Driggers, Edward, Jang, Hyun G., Su, Shinsan M., Schenkein, David P., Lai, Albert, Cloughesy, Timothy F., Kornblum, Harley I., Wu, Hong, Fantin, Valeria R., Liau, Linda M.
Published in Journal of neuro-oncology (01.03.2012)
Published in Journal of neuro-oncology (01.03.2012)
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Journal Article
Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma
Lei, Kecheng, Gu, Xiaoxia, Alvarado, Alvaro G, Du, Yuhong, Luo, Shilin, Ahn, Eun Hee, Kang, Seong Su, Ji, Bing, Liu, Xia, Mao, Hui, Fu, Haian, Kornblum, Harley I, Jin, Lingjing, Li, Hua, Ye, Keqiang
Published in Journal of hematology and oncology (21.10.2020)
Published in Journal of hematology and oncology (21.10.2020)
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P300 promotes tumor recurrence by regulating radiation-induced conversion of glioma stem cells to vascular-like cells
Muthukrishnan, Sree Deepthi, Kawaguchi, Riki, Nair, Pooja, Prasad, Rachna, Qin, Yue, Johnson, Maverick, Wang, Qing, VanderVeer-Harris, Nathan, Pham, Amy, Alvarado, Alvaro G., Condro, Michael C., Gao, Fuying, Gau, Raymond, Castro, Maria G., Lowenstein, Pedro R., Deb, Arjun, Hinman, Jason D., Pajonk, Frank, Burns, Terry C., Goldman, Steven A., Geschwind, Daniel H., Kornblum, Harley I.
Published in Nature communications (19.10.2022)
Published in Nature communications (19.10.2022)
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