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Inhibition of cytochrome P450 3A by clarithromycin uniformly affects the pharmacokinetics and pharmacodynamics of oxycodone in young and elderly volunteers
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Exposure to oral S-ketamine is unaffected by itraconazole but greatly increased by ticlopidine
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Voriconazole drastically increases exposure to oral oxycodone
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Rifampicin markedly decreases the exposure to oral and intravenous tramadol
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Effect of Inhibition of Cytochrome P450 Enzymes 2D6 and 3A4 on the Pharmacokinetics of Intravenous Oxycodone: A Randomized, Three-Phase, Crossover, Placebo-Controlled Study
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Published in Clinical drug investigation (01.01.2011)
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St John's wort greatly reduces the concentrations of oral oxycodone
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Oxycodone concentrations are greatly increased by the concomitant use of ritonavir or lopinavir/ritonavir
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Published in Basic & clinical pharmacology & toxicology (01.11.2012)
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Grapefruit Juice Enhances the Exposure to Oral Oxycodone
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Published in Basic & clinical pharmacology & toxicology (01.10.2010)
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Clarithromycin, a potent inhibitor of CYP3A, greatly increases exposure to oral S-ketamine
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