EPCR expression marks UM171-expanded CD34+ cord blood stem cells
Fares, Iman, Chagraoui, Jalila, Lehnertz, Bernhard, MacRae, Tara, Mayotte, Nadine, Tomellini, Elisa, Aubert, Léo, Roux, Philippe P., Sauvageau, Guy
Published in Blood (22.06.2017)
Published in Blood (22.06.2017)
Get full text
Journal Article
Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
Baccelli, Irène, Gareau, Yves, Lehnertz, Bernhard, Gingras, Stéphane, Spinella, Jean-François, Corneau, Sophie, Mayotte, Nadine, Girard, Simon, Frechette, Mélanie, Blouin-Chagnon, Valérie, Leveillé, Koryne, Boivin, Isabel, MacRae, Tara, Krosl, Jana, Thiollier, Clarisse, Lavallée, Vincent-Philippe, Kanshin, Evgeny, Bertomeu, Thierry, Coulombe-Huntington, Jasmin, St-Denis, Corinne, Bordeleau, Marie-Eve, Boucher, Geneviève, Roux, Philippe P., Lemieux, Sébastien, Tyers, Mike, Thibault, Pierre, Hébert, Josée, Marinier, Anne, Sauvageau, Guy
Published in Cancer cell (08.07.2019)
Published in Cancer cell (08.07.2019)
Get full text
Journal Article
Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
Fares, Iman, Chagraoui, Jalila, Gareau, Yves, Gingras, Stéphane, Ruel, Réjean, Mayotte, Nadine, Csaszar, Elizabeth, Knapp, David J. H. F., Miller, Paul, Ngom, Mor, Imren, Suzan, Roy, Denis-Claude, Watts, Kori L., Kiem, Hans-Peter, Herrington, Robert, Iscove, Norman N., Humphries, R. Keith, Eaves, Connie J., Cohen, Sandra, Marinier, Anne, Zandstra, Peter W., Sauvageau, Guy
Published in Science (American Association for the Advancement of Science) (19.09.2014)
Published in Science (American Association for the Advancement of Science) (19.09.2014)
Get full text
Journal Article
SMARCD2 subunit of SWI/SNF chromatin-remodeling complexes mediates granulopoiesis through a CEBPɛ dependent mechanism
Priam, Pierre, Krasteva, Veneta, Rousseau, Philippe, D'Angelo, Giovanni, Gaboury, Louis, Sauvageau, Guy, Lessard, Julie A
Published in Nature genetics (01.05.2017)
Published in Nature genetics (01.05.2017)
Get full text
Journal Article
Genetic characterization of ABT-199 sensitivity in human AML
Bisaillon, Richard, Moison, Céline, Thiollier, Clarisse, Krosl, Jana, Bordeleau, Marie-Eve, Lehnertz, Bernhard, Lavallée, Vincent-Philippe, MacRae, Tara, Mayotte, Nadine, Labelle, Caroline, Boucher, Geneviève, Spinella, Jean-François, Boivin, Isabel, D’Angelo, Giovanni, Lavallée, Sylvie, Marinier, Anne, Lemieux, Sébastien, Hébert, Josée, Sauvageau, Guy
Published in Leukemia (01.01.2020)
Published in Leukemia (01.01.2020)
Get full text
Journal Article
The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias
Lavallée, Vincent-Philippe, Baccelli, Irène, Krosl, Jana, Wilhelm, Brian, Barabé, Frédéric, Gendron, Patrick, Boucher, Geneviève, Lemieux, Sébastien, Marinier, Anne, Meloche, Sylvain, Hébert, Josée, Sauvageau, Guy
Published in Nature genetics (01.09.2015)
Published in Nature genetics (01.09.2015)
Get full text
Journal Article
UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal
Chagraoui, Jalila, Lehnertz, Bernhard, Girard, Simon, Spinella, Jean Francois, Fares, Iman, Tomellini, Elisa, Mayotte, Nadine, Corneau, Sophie, MacRae, Tara, Simon, Laura, Sauvageau, Guy
Published in PloS one (08.11.2019)
Published in PloS one (08.11.2019)
Get full text
Journal Article
Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors
Lavallée, Vincent-Philippe, Krosl, Jana, Lemieux, Sébastien, Boucher, Geneviève, Gendron, Patrick, Pabst, Caroline, Boivin, Isabel, Marinier, Anne, Guidos, Cynthia J., Meloche, Sylvain, Hébert, Josée, Sauvageau, Guy
Published in Blood (16.06.2016)
Published in Blood (16.06.2016)
Get full text
Journal Article
Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study
Cohen, Sandra, Roy, Jean, Lachance, Silvy, Delisle, Jean-Sébastien, Marinier, Anne, Busque, Lambert, Roy, Denis-Claude, Barabé, Frédéric, Ahmad, Imran, Bambace, Nadia, Bernard, Léa, Kiss, Thomas, Bouchard, Philippe, Caudrelier, Pierre, Landais, Sévérine, Larochelle, Fannie, Chagraoui, Jalila, Lehnertz, Bernhard, Corneau, Sophie, Tomellini, Elisa, van Kampen, Jeroen J A, Cornelissen, Jan J, Dumont-Lagacé, Maude, Tanguay, Mégane, Li, Qi, Lemieux, Sébastien, Zandstra, Peter W, Sauvageau, Guy
Published in The Lancet. Haematology (01.02.2020)
Published in The Lancet. Haematology (01.02.2020)
Get more information
Journal Article
Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance
Buscarlet, Manuel, Krasteva, Veneta, Ho, Lena, Simon, Camille, Hébert, Josée, Wilhelm, Brian, Crabtree, Gerald R., Sauvageau, Guy, Thibault, Pierre, Lessard, Julie A.
Published in Blood (13.03.2014)
Published in Blood (13.03.2014)
Get full text
Journal Article
EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations
Lavallée, Vincent-Philippe, Gendron, Patrick, Lemieux, Sébastien, D’Angelo, Giovanni, Hébert, Josée, Sauvageau, Guy
Published in Blood (01.01.2015)
Published in Blood (01.01.2015)
Get full text
Journal Article
Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia
Supper, Emmanuelle, Rudat, Saskia, Iyer, Vivek, Droop, Alastair, Wong, Kim, Spinella, Jean-François, Thomas, Patrick, Sauvageau, Guy, Adams, David J., Wong, Chi C.
Published in Nature communications (30.04.2021)
Published in Nature communications (30.04.2021)
Get full text
Journal Article
Expression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers
Rouette, Alexandre, Trofimov, Assya, Haberl, David, Boucher, Geneviève, Lavallée, Vincent-Philippe, D’Angelo, Giovanni, Hébert, Josée, Sauvageau, Guy, Lemieux, Sébastien, Perreault, Claude
Published in Scientific reports (23.09.2016)
Published in Scientific reports (23.09.2016)
Get full text
Journal Article
The methyltransferase G9a regulates HoxA9-dependent transcription in AML
Lehnertz, Bernhard, Pabst, Caroline, Su, Le, Miller, Michelle, Liu, Feng, Yi, Lin, Zhang, Regan, Krosl, Jana, Yung, Eric, Kirschner, Jeanette, Rosten, Patty, Underhill, T Michael, Jin, Jian, Hébert, Josée, Sauvageau, Guy, Humphries, R Keith, Rossi, Fabio M
Published in Genes & development (15.02.2014)
Published in Genes & development (15.02.2014)
Get full text
Journal Article
A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene
Gavory, Gwenaëlle, Baril, Caroline, Laberge, Gino, Bidla, Gawa, Koonpaew, Surapong, Sonea, Thomas, Sauvageau, Guy, Therrien, Marc
Published in PLoS genetics (12.08.2021)
Published in PLoS genetics (12.08.2021)
Get full text
Journal Article
RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature
Lavallée, Vincent-Philippe, Lemieux, Sébastien, Boucher, Geneviève, Gendron, Patrick, Boivin, Isabel, Armstrong, Richard N., Sauvageau, Guy, Hébert, Josée
Published in Blood (19.05.2016)
Published in Blood (19.05.2016)
Get full text
Journal Article
Legal and Ethical Considerations for the Design and Use of Web Portals for Researchers, Clinicians, and Patients: Scoping Literature Review
Lang, Michael, Lemieux, Sébastien, Hébert, Josée, Sauvageau, Guy, Zawati, Ma'n H
Published in Journal of medical Internet research (11.11.2021)
Published in Journal of medical Internet research (11.11.2021)
Get full text
Journal Article
A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2
Dubois, Emilie L, Guitton-Sert, Laure, Béliveau, Mariline, Parmar, Kalindi, Chagraoui, Jalila, Vignard, Julien, Pauty, Joris, Caron, Marie-Christine, Coulombe, Yan, Buisson, Rémi, Jacquet, Karine, Gamblin, Clémence, Gao, Yuandi, Laprise, Patrick, Lebel, Michel, Sauvageau, Guy, D. d’Andrea, Alan, Masson, Jean-Yves
Published in Nucleic acids research (22.08.2019)
Published in Nucleic acids research (22.08.2019)
Get full text
Journal Article