Synthesis and Physicochemical Characterization of the Process-Related Impurities of Olmesartan Medoxomil. Do 5-(Biphenyl-2-yl)-1-triphenylmethyltetrazole Intermediates in Sartan Syntheses Exist?
Dams, Iwona, Ostaszewska, Anna, Puchalska, Maria, Chmiel, Justyna, Cmoch, Piotr, Bujak, Iwona, Białońska, Agata, Szczepek, Wojciech J
Published in Molecules (Basel, Switzerland) (01.12.2015)
Published in Molecules (Basel, Switzerland) (01.12.2015)
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New Polymorphic Forms of Pemetrexed Diacid and Their Use for the Preparation of Pharmaceutically Pure Amorphous and Hemipentahydrate Forms of Pemetrexed Disodium
Michalak, Olga, Łaszcz, Marta, Jatczak, Kamil, Witkowska, Anna, Bujak, Iwona, Groman, Aleksandra, Cybulski, Marcin
Published in Molecules (Basel, Switzerland) (30.07.2015)
Published in Molecules (Basel, Switzerland) (30.07.2015)
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The synthesis of indolo[2,3-b]quinoline derivatives with a guanidine group: Highly selective cytotoxic agents
Sidoryk, Katarzyna, Świtalska, Marta, Jaromin, Anna, Cmoch, Piotr, Bujak, Iwona, Kaczmarska, Monika, Wietrzyk, Joanna, Dominguez, Eddie G., Żarnowski, Robert, Andes, David R., Bańkowski, Krzysztof, Cybulski, Marcin, Kaczmarek, Łukasz
Published in European journal of medicinal chemistry (13.11.2015)
Published in European journal of medicinal chemistry (13.11.2015)
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Journal Article
An efficient synthesis of indolo[2,3-b]quinoline guanidine derivatives with their in vitro and in vivo study
Sidoryk, Katarzyna, Świtalska, Marta, Rózga, Piotr, Wietrzyk, Joanna, Bujak, Iwona, Żerek, Bartłomiej, Kaczmarek, Łukasz, Cybulski, Marcin
Published in Medicinal chemistry research (2017)
Published in Medicinal chemistry research (2017)
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Journal Article
Synthesis and physicochemical characterization of the impurities and the key intermediate of pemetrexed disodium, an anticancer drug
Michalak, Olga, Gruza, Mariusz, Łaszcz, Marta, Trzcińska, Kinga, Witkowska, Anna, Bujak, Iwona, Cmoch, Piotr
Published in PeerJ preprints (30.03.2016)
Published in PeerJ preprints (30.03.2016)
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Journal Article
PROCESS FOR THE PREPARATION OF HIGH PURITY AMORPHOUS PEMETREXED DISODIUM AND CRYSTALLINE FORMS OF N-[4-[2-(2-AMINO-4,7-DIHYDRO-4-OXO-3H-PYRROLO[2,3- D]PYRIMIDIN-5-YL)ETHYL]BENZOYL]-L-GLUTAMIC ACID
CYBULSKI, MARCIN, GROMAN, ALEKSANDRA, JATCZAK, KAMIL, PUCKO, WIESLAW, BUJAK, IWONA, WITKOWSKA, ANNA, LASZCZ, MARTA, MICHALAK, OLGA
Year of Publication 23.03.2016
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Year of Publication 23.03.2016
Patent
PROCESS FOR THE PREPARATION OF HIGH PURITY AMORPHOUS PEMETREXED DISODIUM AND CRYSTALLINE FORMS OF N-[4-[2-(2-AMINO-4,7-DIHYDRO-4-OXO-3H-PYRROLO[2,3- D] PYRIMIDIN-5-YL)ETHYL] BENZOYL]-L-GLUTAMIC ACID
CYBULSKI, MARCIN, GROMAN, ALEKSANDRA, JATCZAK, KAMIL, BUJAK, IWONA, PUCKO, WIES AW, WITKOWSKA, ANNA, MICHALAK, OLGA, ASZCZ, MARTA
Year of Publication 20.11.2014
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Year of Publication 20.11.2014
Patent
New impurity in the synthesis of olmesartan medoxomil
SZCZEPEK WOJCIECH J, OSTASZEWSKA ANNA, DAMS IWONA, CMOCH PIOTR, CHMIEL JUSTYNA, PUCHALSKA MARIA, BUJAK IWONA
Year of Publication 12.09.2016
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Year of Publication 12.09.2016
Patent
Method for producing pemetrexed disodium salt in high purity amorphous form and the crystalline forms of N-[4-(2-(-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid
JATCZAK KAMIL, GROMAN ALEKSANDRA, WITKOWSKA ANNA, MICHALAK OLGA, ASZCZ MARTA, PUCKO WIES AW, BUJAK IWONA, CYBULSKI MARCIN
Year of Publication 09.11.2015
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Year of Publication 09.11.2015
Patent
Method for preparing the disodium salt of pemetrexed in amorphous form of high purity
JATCZAK KAMIL, TRZCI SKA KINGA, WITKOWSKA ANNA, MICHALAK OLGA, ASZCZ MARTA, KO CIUCH MARTA, ZAGRODZKA JOANNA, KUTNER ANDRZEJ, BUJAK IWONA
Year of Publication 24.11.2014
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Year of Publication 24.11.2014
Patent