Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout mice
Winter, Aimee N, Subbarayan, Meena S, Grimmig, Bethany, Weesner, Jason A, Moss, Lauren, Peters, Melinda, Weeber, Edwin, Nash, Kevin, Bickford, Paula C
Published in Journal of neuroinflammation (14.05.2020)
Published in Journal of neuroinflammation (14.05.2020)
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Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis model
Weesner, Jason A., Annunziata, Ida, van de Vlekkert, Diantha, Robinson, Camenzind G., Campos, Yvan, Mishra, Ashutosh, Fremuth, Leigh E., Gomero, Elida, Hu, Huimin, d’Azzo, Alessandra
Published in Cell reports (Cambridge) (28.05.2024)
Published in Cell reports (Cambridge) (28.05.2024)
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AAV-mediated gene therapy for galactosialidosis: A long-term safety and efficacy study
Hu, Huimin, Mosca, Rosario, Gomero, Elida, van de Vlekkert, Diantha, Campos, Yvan, Fremuth, Leigh E., Brown, Scott A., Weesner, Jason A., Annunziata, Ida, d’Azzo, Alessandra
Published in Molecular therapy. Methods & clinical development (10.12.2021)
Published in Molecular therapy. Methods & clinical development (10.12.2021)
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Journal Article
AAV-mediated gene therapy for sialidosis
van de Vlekkert, Diantha, Hu, Huimin, Weesner, Jason A., Fremuth, Leigh E., Brown, Scott A., Lu, Meifen, Gomero, Elida, Campos, Yvan, Sheppard, Heather, d’Azzo, Alessandra
Published in Molecular therapy (03.07.2024)
Published in Molecular therapy (03.07.2024)
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Journal Article
Distinct functions of dimeric and monomeric scaffold protein Alix in regulating F-actin assembly and loading of exosomal cargo
Qiu, Xiaohui, Campos, Yvan, van de Vlekkert, Diantha, Gomero, Elida, Tanwar, Ajay C., Kalathur, Ravi, Weesner, Jason A., Bongiovanni, Antonella, Demmers, Jeroen, d’Azzo, Alessandra
Published in The Journal of biological chemistry (01.10.2022)
Published in The Journal of biological chemistry (01.10.2022)
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Journal Article
AAV-mediated gene therapy in a mouse model of sialidosis
van de Vlekkert, Diantha, Hu, Huimin, Weesner, Jason A., Gomero, Elida M., d'Azzo, Alessandra
Published in Molecular genetics and metabolism (01.02.2023)
Published in Molecular genetics and metabolism (01.02.2023)
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Journal Article
Preclinical enzyme replacement therapy with a recombinant β-galactosidase-lectin fusion for CNS delivery and treatment of GM1-gangliosidosis
Weesner, Jason A., van de Vlekkert, Diantha, Acosta, Walter L., Yang, Tianhong, Gomero, Elida M., Hu, Huimin, Radin, David, Cramer, Carole L., d'Azzo, Alessandra
Published in Molecular genetics and metabolism (01.02.2023)
Published in Molecular genetics and metabolism (01.02.2023)
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Journal Article
Altered GM1 catabolism affects NMDAR-mediated Ca 2+ signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis model
Weesner, Jason A, Annunziata, Ida, van de Vlekkert, Diantha, Robinson, Camenzind G, Campos, Yvan, Mishra, Ashutosh, Fremuth, Leigh E, Gomero, Elida, Hu, Huimin, d'Azzo, Alessandra
Published in Cell reports (Cambridge) (28.05.2024)
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Published in Cell reports (Cambridge) (28.05.2024)
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