ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression
Cao, Yu, Trillo-Tinoco, Jimena, Sierra, Rosa A., Anadon, Carmen, Dai, Wenjie, Mohamed, Eslam, Cen, Ling, Costich, Tara L., Magliocco, Anthony, Marchion, Douglas, Klar, Richard, Michel, Sven, Jaschinski, Frank, Reich, Richard R., Mehrotra, Shikhar, Cubillos-Ruiz, Juan R., Munn, David H., Conejo-Garcia, Jose R., Rodriguez, Paulo C.
Published in Nature communications (20.03.2019)
Published in Nature communications (20.03.2019)
Get full text
Journal Article
Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance
Sierra, Rosa A, Trillo-Tinoco, Jimena, Mohamed, Eslam, Yu, Lolie, Achyut, Bhagelu R, Arbab, Ali, Bradford, Jennifer W, Osborne, Barbara A, Miele, Lucio, Rodriguez, Paulo C
Published in Cancer research (Chicago, Ill.) (15.10.2017)
Published in Cancer research (Chicago, Ill.) (15.10.2017)
Get full text
Journal Article
The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
de Mingo Pulido, Álvaro, Hänggi, Kay, Celias, Daiana P., Gardner, Alycia, Li, Jie, Batista-Bittencourt, Bruna, Mohamed, Eslam, Trillo-Tinoco, Jimena, Osunmakinde, Olabisi, Peña, Reymi, Onimus, Alexis, Kaisho, Tsuneyasu, Kaufmann, Johanna, McEachern, Kristen, Soliman, Hatem, Luca, Vincent C., Rodriguez, Paulo C., Yu, Xiaoqing, Ruffell, Brian
Published in Immunity (Cambridge, Mass.) (08.06.2021)
Published in Immunity (Cambridge, Mass.) (08.06.2021)
Get full text
Journal Article
IgA transcytosis and antigen recognition govern ovarian cancer immunity
Biswas, Subir, Mandal, Gunjan, Payne, Kyle K., Anadon, Carmen M., Gatenbee, Chandler D., Chaurio, Ricardo A., Costich, Tara Lee, Moran, Carlos, Harro, Carly M., Rigolizzo, Kristen E., Mine, Jessica A., Trillo-Tinoco, Jimena, Sasamoto, Naoko, Terry, Kathryn L., Marchion, Douglas, Buras, Andrea, Wenham, Robert M., Yu, Xiaoqing, Townsend, Mary K., Tworoger, Shelley S., Rodriguez, Paulo C., Anderson, Alexander R., Conejo-Garcia, Jose R.
Published in Nature (London) (18.03.2021)
Published in Nature (London) (18.03.2021)
Get full text
Journal Article
Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies
Hossain, Fokhrul, Al-Khami, Amir A, Wyczechowska, Dorota, Hernandez, Claudia, Zheng, Liqin, Reiss, Krzystoff, Valle, Luis Del, Trillo-Tinoco, Jimena, Maj, Tomasz, Zou, Weiping, Rodriguez, Paulo C, Ochoa, Augusto C
Published in Cancer immunology research (01.11.2015)
Published in Cancer immunology research (01.11.2015)
Get more information
Journal Article
The Stress-Response Sensor Chop Regulates the Function and Accumulation of Myeloid-Derived Suppressor Cells in Tumors
Thevenot, Paul T., Sierra, Rosa A., Raber, Patrick L., Al-Khami, Amir A., Trillo-Tinoco, Jimena, Zarreii, Parisa, Ochoa, Augusto C., Cui, Yan, Del Valle, Luis, Rodriguez, Paulo C.
Published in Immunity (Cambridge, Mass.) (18.09.2014)
Published in Immunity (Cambridge, Mass.) (18.09.2014)
Get full text
Journal Article
Targeting HGF/c-MET induces cell cycle arrest, DNA damage, and apoptosis for primary effusion lymphoma
Dai, Lu, Trillo-Tinoco, Jimena, Cao, Yueyu, Bonstaff, Karlie, Doyle, Lisa, Del Valle, Luis, Whitby, Denise, Parsons, Chris, Reiss, Krzysztof, Zabaleta, Jovanny, Qin, Zhiqiang
Published in Blood (24.12.2015)
Published in Blood (24.12.2015)
Get full text
Journal Article
Activation of c-Myc and Cyclin D1 by JCV T-Antigen and β-catenin in colon cancer
Ripple, Michael J, Parker Struckhoff, Amanda, Trillo-Tinoco, Jimena, Li, Li, Margolin, David A, McGoey, Robin, Del Valle, Luis
Published in PloS one (17.09.2014)
Published in PloS one (17.09.2014)
Get full text
Journal Article
Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma
Qin, Zhiqiang, Dai, Lu, Trillo-Tinoco, Jimena, Senkal, Can, Wang, Wenxue, Reske, Tom, Bonstaff, Karlie, Del Valle, Luis, Rodriguez, Paulo, Flemington, Erik, Voelkel-Johnson, Christina, Smith, Charles D, Ogretmen, Besim, Parsons, Chris
Published in Molecular cancer therapeutics (01.01.2014)
Published in Molecular cancer therapeutics (01.01.2014)
Get full text
Journal Article
Systematic analysis of a xenograft mice model for KSHV+ primary effusion lymphoma (PEL)
Dai, Lu, Trillo-Tinoco, Jimena, Bai, Lihua, Kang, Baoli, Xu, Zengguang, Wen, Xiaofei, Del Valle, Luis, Qin, Zhiqiang
Published in PloS one (28.02.2014)
Published in PloS one (28.02.2014)
Get full text
Journal Article
Differential expression of miRNA-146a and miRNA-155 in gastritis induced by Helicobacter pylori infection in paediatric patients, adults, and an animal model
Cortés-Márquez, Ana Caren, Mendoza-Elizalde, Sandra, Arenas-Huertero, Francisco, Trillo-Tinoco, Jimena, Valencia-Mayoral, Pedro, Consuelo-Sánchez, Alejandra, Zarate-Franco, Jonathan, Dionicio-Avendaño, Ada Ruth, Herrera-Esquivel, José de Jesús, Recinos-Carrera, Elio Germán, Colín-Valverde, Christian, Rivera-Gutiérrez, Sandra, Reyes-López, Alfonso, Vigueras-Galindo, Juan Carlos, Velázquez-Guadarrama, Norma
Published in BMC infectious diseases (15.09.2018)
Published in BMC infectious diseases (15.09.2018)
Get full text
Journal Article
Publisher Correction: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression
Cao, Yu, Trillo-Tinoco, Jimena, Sierra, Rosa A., Anadon, Carmen, Dai, Wenjie, Mohamed, Eslam, Cen, Ling, Costich, Tara L., Magliocco, Anthony, Marchion, Douglas, Klar, Richard, Michel, Sven, Jaschinski, Frank, Reich, Richard R., Mehrotra, Shikhar, Cubillos-Ruiz, Juan R., Munn, David H., Conejo-Garcia, Jose R., Rodriguez, Paulo C.
Published in Nature communications (15.08.2019)
Published in Nature communications (15.08.2019)
Get full text
Journal Article
292 Ex vivo profiling of PD-1 blockade using an organotypic tissue slice model in solid tumors
Ding, Lina, Sullivan, Kristin, Zhou, Chensheng, Trillo-Tinoco, Jimena, Lewin, Anne, King, Catherine, Nelson, David, Chen, Benjamin, Bowden, Michaela
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
Get full text
Journal Article
387 The utility of AI-powered spatial classification of intratumoral CD8+ immune-cell distribution in predicting overall survival in patients with melanoma as part of the checkMate 067 clinical trial
Lee, George, Desai, Keyur, Tang, Hao, Cohen, Daniel, Ely, Scott, Wojcik, John, Trillo-Tinoco, Jimena, Chen, Benjamin, Gupta, Akshita, Tenney, Daniel, Baxi, Vipul, Edwards, Robin, Wind-Rotolo, Megan
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
Get full text
Journal Article
733 Integrative molecular profiling of high-grade primary prostate cancer identifies patients with a biomarker profile that favors the combination of standard of care (SOC) therapy with immunotherapy
Gjini, Evisa, Trillo-Tinoco, Jimena, Browne, Andrew, Powles, Ryan, Wang, Tai, Tauras, Christine, Lako, Ana, Ferrer-Luna, Ruben, Bleicher, Zoe, Consedine, Timothy, Zhou, Chensheng, Kelemen, Evan, Lewin, Anne, King, Catherine, Bhattacharya, Sumit, Bell-Temin, Harris, Dongre, Ashok, Nelson, David, Hatzis, Christos, Macisaac, Kenzie, Towfic, Fadi, Chen, Benjamin, Bowden, Michaela
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
Get full text
Journal Article
The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling
Mohamed, Eslam, Sierra, Rosa A., Trillo-Tinoco, Jimena, Cao, Yu, Innamarato, Patrick, Payne, Kyle K., de Mingo Pulido, Alvaro, Mandula, Jessica, Zhang, Shuzhong, Thevenot, Paul, Biswas, Subir, Abdalla, Sarah K., Costich, Tara Lee, Hänggi, Kay, Anadon, Carmen M., Flores, Elsa R., Haura, Eric B., Mehrotra, Shikhar, Pilon-Thomas, Shari, Ruffell, Brian, Munn, David H., Cubillos-Ruiz, Juan R., Conejo-Garcia, Jose R., Rodriguez, Paulo C.
Published in Immunity (Cambridge, Mass.) (14.04.2020)
Published in Immunity (Cambridge, Mass.) (14.04.2020)
Get full text
Journal Article
Expression of cancer cell-associated Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) regulates protective anti-tumor immunity in melanoma
Mandula, Jessica, Mohamed, Eslam, Sierra-Mondragon, Rosa, Cao, Yu, Trillo-Tinoco, Jimena, Rodriguez, Paulo
Published in The Journal of immunology (1950) (01.05.2020)
Published in The Journal of immunology (1950) (01.05.2020)
Get full text
Journal Article
Effective antitumor peptide vaccines can induce severe autoimmune pathology
Sultan, Hussein, Trillo-Tinoco, Jimena, Rodriguez, Paulo, Celis, Esteban
Published in Oncotarget (19.09.2017)
Published in Oncotarget (19.09.2017)
Get full text
Journal Article
AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells
Trillo-Tinoco, Jimena, Sierra, Rosa A, Mohamed, Eslam, Cao, Yu, de Mingo-Pulido, Álvaro, Gilvary, Danielle L, Anadon, Carmen M, Costich, Tara Lee, Wei, Sheng, Flores, Elsa R, Ruffell, Brian, Conejo-Garcia, José R, Rodriguez, Paulo C
Published in Cancer research (Chicago, Ill.) (01.10.2019)
Published in Cancer research (Chicago, Ill.) (01.10.2019)
Get full text
Journal Article
Sildenafil Suppresses Inflammation-Driven Colorectal Cancer in Mice
Islam, Bianca N, Sharman, Sarah K, Hou, Yali, Bridges, Allison E, Singh, Nagendra, Kim, Sangmi, Kolhe, Ravindra, Trillo-Tinoco, Jimena, Rodriguez, Paulo C, Berger, Franklin G, Sridhar, Subbaramiah, Browning, Darren D
Published in Cancer prevention research (Philadelphia, Pa.) (01.07.2017)
Published in Cancer prevention research (Philadelphia, Pa.) (01.07.2017)
Get full text
Journal Article