A T cell receptor β chain-directed antibody fusion molecule activates and expands subsets of T cells to promote antitumor activity
Hsu, Jonathan, Donahue, Renee N, Katragadda, Madan, Lowry, Jessica, Huang, Wei, Srinivasan, Karunya, Guntas, Gurkan, Tang, Jian, Servattalab, Roya, Moisan, Jacques, Tsai, Yo-Ting, Stoop, Allart, Palakurthi, Sangeetha, Chopra, Raj, Liu, Ke, Wherry, E John, Su, Zhen, Gulley, James L, Bayliffe, Andrew, Schlom, Jeffrey
Published in Science translational medicine (29.11.2023)
Published in Science translational medicine (29.11.2023)
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Abstract 2357: T cell receptor beta chain-directed Tri-specific antibody molecules retarget V-beta T cell subsets to tumors to promote potent and durable antitumor activity
Katragadda, Madan, Moisan, Jacques, Guntas, Gurkan, Sequeria, Manuel, Servattalab, Roya, Lowry, Jessica, Ruidera, Robert, Nybakken, Kent, Gerson, Erik, Liu, Ke, Chin, Kevin, Su, Zhen, Bayliffe, Andrew
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract LB338: A novel class of T cell-activators targeting germline encoded TCRβ chains promotes antitumor activity in PD1-refractory models through expansion of a clonally enriched effector memory T cell subset
Moisan, Jacques, Katraggada, Madan, Hsu, Jonathan, Lowry, Jessica, Huang, Wei, Tang, Jian, Servattalab, Roya, Guntas, Gurkan, Chopra, Raj, Su, Zhen, Bayliffe, Andrew
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Innate TCRβ-chain engagement drives human T cells toward distinct memory-like effector phenotypes with immunotherapeutic potentials
Vantourout, Pierre, Eum, Josephine, Conde Poole, María, Hayday, Thomas S, Laing, Adam G, Hussain, Khiyam, Nuamah, Rosamond, Kannambath, Shichina, Moisan, Jacques, Stoop, Allart, Battaglia, Sebastiano, Servattalab, Roya, Hsu, Jonathan, Bayliffe, Andrew, Katragadda, Madan, Hayday, Adrian C
Published in Science advances (08.12.2023)
Published in Science advances (08.12.2023)
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