Search Results - "TIMONY, Gregg" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Results From the First‐in‐Human Study With Ozanimod, a Novel, Selective Sphingosine‐1‐Phosphate Receptor Modulator

Results From the First‐in‐Human Study With Ozanimod, a Novel, Selective Sphingosine‐1‐Phosphate Receptor Modulator

by Tran, Jonathan Q., Hartung, Jeffrey P., Peach, Robert J., Boehm, Marcus F., Rosen, Hugh, Smith, Heather, Brooks, Jennifer L., Timony, Gregg A., Olson, Allan D., Gujrathi, Sheila, Frohna, Paul A.
Published in Journal of clinical pharmacology (01.08.2017)

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Journal Article

Cardiac Safety of Ozanimod, a Novel Sphingosine‐1‐Phosphate Receptor Modulator: Results of a Thorough QT/QTc Study

Cardiac Safety of Ozanimod, a Novel Sphingosine‐1‐Phosphate Receptor Modulator: Results of a Thorough QT/QTc Study

by Tran, Jonathan Q., Hartung, Jeffrey P., Olson, Allan D., Mendzelevski, Boaz, Timony, Gregg A., Boehm, Marcus F., Peach, Robert J., Gujrathi, Sheila, Frohna, Paul A.
Published in Clinical pharmacology in drug development (01.03.2018)

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Rationally Designed High-Affinity 2-Amino-6-halopurine Heat Shock Protein 90 Inhibitors That Exhibit Potent Antitumor Activity

Rationally Designed High-Affinity 2-Amino-6-halopurine Heat Shock Protein 90 Inhibitors That Exhibit Potent Antitumor Activity

by Kasibhatla, Srinivas R, Hong, Kevin, Biamonte, Marco A, Busch, David J, Karjian, Patricia L, Sensintaffar, John L, Kamal, Adeela, Lough, Rachel E, Brekken, John, Lundgren, Karen, Grecko, Roy, Timony, Gregg A, Ran, Yingqing, Mansfield, Robert, Fritz, Lawrence C, Ulm, Edgar, Burrows, Francis J, Boehm, Marcus F
Published in Journal of medicinal chemistry (14.06.2007)

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Journal Article

7‘-Substituted Benzothiazolothio- and Pyridinothiazolothio-Purines as Potent Heat Shock Protein 90 Inhibitors

7‘-Substituted Benzothiazolothio- and Pyridinothiazolothio-Purines as Potent Heat Shock Protein 90 Inhibitors

by Zhang, Lin, Fan, Junhua, Vu, Khang, Hong, Kevin, Le Brazidec, Jean-Yves, Shi, Jiandong, Biamonte, Marco, Busch, David J, Lough, Rachel E, Grecko, Roy, Ran, Yingqing, Sensintaffar, John L, Kamal, Adeela, Lundgren, Karen, Burrows, Francis J, Mansfield, Robert, Timony, Gregg A, Ulm, Edgar H, Kasibhatla, Srinivas R, Boehm, Marcus F
Published in Journal of medicinal chemistry (24.08.2006)

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Orally Active Purine-Based Inhibitors of the Heat Shock Protein 90

Orally Active Purine-Based Inhibitors of the Heat Shock Protein 90

by Biamonte, Marco A, Shi, Jiandong, Hong, Kevin, Hurst, David C, Zhang, Lin, Fan, Junhua, Busch, David J, Karjian, Patricia L, Maldonado, Angelica A, Sensintaffar, John L, Yang, Yong-Ching, Kamal, Adeela, Lough, Rachel E, Lundgren, Karen, Burrows, Francis J, Timony, Gregg A, Boehm, Marcus F, Kasibhatla, Srinivas R
Published in Journal of medicinal chemistry (26.01.2006)

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Pharmacokinetics, Pharmacodynamics, Allometry, and Dose Selection of rPSGL-Ig for Phase I Trial

Pharmacokinetics, Pharmacodynamics, Allometry, and Dose Selection of rPSGL-Ig for Phase I Trial

by Khor, S P, McCarthy, K, DuPont, M, Murray, K, Timony, G
Published in The Journal of pharmacology and experimental therapeutics (01.05.2000)

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Journal Article

IL-13 IL-13 METHODS OF TREATMENT OF DISEASES IN WHICH IL-13 ACTIVITY IS DETRIMENTAL USING ANTI-IL-13 ANTIBODIES

IL-13 IL-13 METHODS OF TREATMENT OF DISEASES IN WHICH IL-13 ACTIVITY IS DETRIMENTAL USING ANTI-IL-13 ANTIBODIES

by PEACH ROBERT, TIMONY GREGG, OLSON ALLAN, GUJRATHI SHEILA
Year of Publication 23.04.2024

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Patent

Inhibition of mast cell degranulation by novel small molecule MRGPRX2 antagonists

Inhibition of mast cell degranulation by novel small molecule MRGPRX2 antagonists

by Wollam, Joshua, Solomon, Michelle, Villescaz, Christiane, Lanier, Marion, Evans, Samantha, Bacon, Corinne, Freeman, David, Vasquez, Alexis, Vest, Alan, Napora, Jim, Charlot, Brittney, Cavarlez, Christine, Kim, Andrew, Dvorak, Lisa, Selfridge, Brandon, Huang, Liming, Nevarez, Andres, Dedman, Harry, Brooks, Jennifer, Frischbutter, Stefan, Metz, Martin, Serhan, Nadine, Gaudenzio, Nicolas, Timony, Gregg, Martinborough, Esther, Boehm, Marcus F., Viswanath, Veena
Published in Journal of allergy and clinical immunology (01.10.2024)

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Journal Article

IL-13 IL-13 METHODS OF TREATMENT OF DISEASES IN WHICH IL-13 ACTIVITY IS DETRIMENTAL USING ANTI-IL-13 ANTIBODIES

IL-13 IL-13 METHODS OF TREATMENT OF DISEASES IN WHICH IL-13 ACTIVITY IS DETRIMENTAL USING ANTI-IL-13 ANTIBODIES

by PEACH ROBERT, TIMONY GREGG, OLSON ALLAN, GUJRATHI SHEILA
Year of Publication 03.11.2022

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Patent

MRGPRX2 Antagonist EP262 Potently Inhibits Agonist-Induced Mast Cell Degranulation In Vitro and In Vivo

MRGPRX2 Antagonist EP262 Potently Inhibits Agonist-Induced Mast Cell Degranulation In Vitro and In Vivo

by Wollam, Joshua, Solomon, Michelle, Villescaz, Christiane, Lanier, Marion, Brooks, Jennifer, Kim, Andrew, Anderson, Samantha, Freeman, David, Vasquez, Alexis, Pisacane, Corinne, Charlot, Brittney, Vest, Alan, Napora, Jim, Cavarlez, Christine, Dvorak, Lisa, Selfridge, Brandon, Huang, Liming, Sainz, Marcos, Nevarez, Andres, Dedman, Harry, Timony, Gregg, Martinborough, Esther, Viswanath, Veena, Boehm, Marcus
Published in Journal of allergy and clinical immunology (01.02.2023)

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Journal Article

항-IL-13 항체를 이용한 IL-13 활성이 유해한 질환의 치료 방법

항-IL-13 항체를 이용한 IL-13 활성이 유해한 질환의 치료 방법

by PEACH ROBERT, TIMONY GREGG, OLSON ALLAN, GUJRATHI SHEILA
Year of Publication 08.01.2019

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Patent

Sa1222 Results of a Safety and Tolerability Study of Rpc1063, a Novel Orally Administered Sphingosine-1-Phosphate Receptor 1 (S1p1r) Agonist, in Healthy Adult Volunteers

Sa1222 Results of a Safety and Tolerability Study of Rpc1063, a Novel Orally Administered Sphingosine-1-Phosphate Receptor 1 (S1p1r) Agonist, in Healthy Adult Volunteers

by Olson, Allan, Timony, Gregg, Hartung, Jeffrey P, Smith, Heather, Peach, Robert J, Rosen, Hugh, Pan, Christine, Brooks, Jennifer, Boehm, Marcus, Gujrathi, Sheila
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)

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Journal Article

358 A Small Molecule S1P1 Receptor Agonist With Significant Efficacy in Animal Models of Inflammatory Bowel Disease (IBD)

358 A Small Molecule S1P1 Receptor Agonist With Significant Efficacy in Animal Models of Inflammatory Bowel Disease (IBD)

by Clemons, Bryan, Dedman, Harry, Powell, Rachel, Martinborough, Esther, Timony, Gregg, Peach, Robert J, Scott, Fiona L
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)

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Sa1221 Rpc1063, a Potent, Selective S1P1 Receptor Modulator, Is Active in a Therapeutic IBD Model and Exhibits Favorable PK/PD Properties in Healthy Volunteers

Sa1221 Rpc1063, a Potent, Selective S1P1 Receptor Modulator, Is Active in a Therapeutic IBD Model and Exhibits Favorable PK/PD Properties in Healthy Volunteers

by Brooks, Jennifer, Peach, Robert J, Boehm, Marcus, Brahmachary, Enugurthi, Clemons, Bryan, Dedman, Harry, Desale, Hans, Gujrathi, Sheila, Huang, Liming, Hartung, Jeffrey P, Martinborough, Esther, Moorjani, Manisha, Powell, Rachel, Reinhart, Greg, Scott, Fiona L, Tamiya, Junko, Yeager, Adam, Rosen, Hugh, Timony, Gregg
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)

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Journal Article

Synthesis and Biological Evaluation of a New Class of Geldanamycin Derivatives as Potent Inhibitors of Hsp90

Synthesis and Biological Evaluation of a New Class of Geldanamycin Derivatives as Potent Inhibitors of Hsp90

by Le Brazidec, Jean-Yves, Kamal, Adeela, Busch, David, Thao, Lia, Zhang, Lin, Timony, Gregg, Grecko, Roy, Trent, Katy, Lough, Rachel, Salazar, Tim, Khan, Samina, Burrows, Francis, Boehm, Marcus F
Published in Journal of medicinal chemistry (15.07.2004)

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Journal Article

1 SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYSTHESIS

1 SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYSTHESIS

by TAMIYA JUNKO, BROOKS JENNIFER L, YEAGER ADAM RICHARD, MOORJANI MANISHA, MARTINBOROUGH ESTHER, PEACH ROBERT, HUANG LIMING, SCOTT FIONA LORRAINE, BRAHMACHARY ENUGURTHI, BOEHM MARCUS F, TIMONY GREGG ALAN, HANSON MICHAEL ALLEN
Year of Publication 27.12.2016

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Patent

METHODS OF TREATMENT OF DISEASES IN WHICH IL-13 ACTIVITY IS DETRIMENTAL USING ANTI-IL-13 ANTIBODIES

METHODS OF TREATMENT OF DISEASES IN WHICH IL-13 ACTIVITY IS DETRIMENTAL USING ANTI-IL-13 ANTIBODIES

by Gujrathi, Sheila, Timony, Gregg, Peach, Robert, Olson, Allan
Year of Publication 27.09.2024

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Patent

METHODS OF TREATMENT OF DISEASES IN WHICH IL-13 ACTIVITY IS DETRIMENTAL USING ANTI-IL-13 ANTIBODIES

METHODS OF TREATMENT OF DISEASES IN WHICH IL-13 ACTIVITY IS DETRIMENTAL USING ANTI-IL-13 ANTIBODIES

by PEACH, ROBERT, GUJRATHI, SHEILA, OLSON, ALLAN, TIMONY, GREGG
Year of Publication 16.09.2024

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Patent

METHODS OF TREATMENT OF DISEASES IN WHICH IL-13 ACTIVITY IS DETRIMENTAL USING ANTI-IL-13 ANTIBODIES

METHODS OF TREATMENT OF DISEASES IN WHICH IL-13 ACTIVITY IS DETRIMENTAL USING ANTI-IL-13 ANTIBODIES

by TIMONY Gregg, OLSON Allan, GUJRATHI Sheila, PEACH Robert
Year of Publication 30.08.2024

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Patent

Methods of treatment of diseases in which IL-13 activity is detrimental using anti-IL-13 antibodies

Methods of treatment of diseases in which IL-13 activity is detrimental using anti-IL-13 antibodies

by GUJRATHI, Sheila, OLSON, Allan, PEACH, Robert, TIMONY, Gregg
Year of Publication 08.08.2024

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Patent

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