Discovery of a Pharmacologically Active Antagonist of the Two-Pore-Domain Potassium Channel K2P9.1 (TASK-3)
Coburn, Craig A., Luo, Yunfu, Cui, Mingxiang, Wang, Jiabing, Soll, Richard, Dong, Jingchao, Hu, Bin, Lyon, Michael A., Santarelli, Vincent P., Kraus, Richard L., Gregan, Yun, Wang, Yi, Fox, Steven V., Binns, Jacquelyn, Doran, Scott M., Reiss, Duane R., Tannenbaum, Pamela L., Gotter, Anthony L., Meinke, Peter T., Renger, John J.
Published in ChemMedChem (02.01.2012)
Published in ChemMedChem (02.01.2012)
Get full text
Journal Article
Identification, structural, and biophysical characterization of a positive modulator of human Kv3.1 channels
Chen, Yun-Ting, Hong, Mee Ra, Zhang, Xin-Jun, Kostas, James, Li, Yuxing, Kraus, Richard L, Santarelli, Vincent P, Wang, Deping, Gomez-Llorente, Yacob, Brooun, Alexei, Strickland, Corey, Soisson, Stephen M, Klein, Daniel J, Ginnetti, Anthony T, Marino, Michael J, Stachel, Shawn J, Ishchenko, Andrii
Published in Proceedings of the National Academy of Sciences - PNAS (17.10.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (17.10.2023)
Get full text
Journal Article
Analgesia and peripheral c-fiber modulation by selective Nav1.8 inhibition in rhesus
Vardigan, Joshua D, Pall, Parul S, McDevitt, Dillon S, Huang, ChienJung, Clements, Michelle K, Li, Yuxing, Kraus, Richard L, Breslin, Michael J, Bungard, Christopher J, Nemenov, Mikhail I, Klukinov, Mikhail, Burgey, Chritopher S, Layton, Mark E, Stachel, Shawn J, Lange, Henry S, Savitz, Alan T, Santarelli, Vincent P, Henze, Darrell A, Uslaner, Jason M
Published in Pain (Amsterdam) (08.10.2024)
Published in Pain (Amsterdam) (08.10.2024)
Get full text
Journal Article
Functional TASK-3–Like Channels in Mitochondria of Aldosterone-Producing Zona Glomerulosa Cells
Yao, Junlan, McHedlishvili, David, McIntire, William E, Guagliardo, Nick A, Erisir, Alev, Coburn, Craig A, Santarelli, Vincent P, Bayliss, Douglas A, Barrett, Paula Q
Published in Hypertension (Dallas, Tex. 1979) (01.08.2017)
Published in Hypertension (Dallas, Tex. 1979) (01.08.2017)
Get full text
Journal Article
2‑Aminopyridines as Potent and Selective Nav1.8 Inhibitors Exhibiting Efficacy in a Nonhuman Primate Pain Model
Breslin, Michael J., Schubert, Jeffrey W., Wang, Deping, Huang, Chienjung, Clements, Michelle K., Li, Yuxing, Zhou, Xiaoping, Vardigan, Joshua D., Kraus, Richard L., Santarelli, Vincent P., Uslaner, Jason M., Coleman, Paul J., Stachel, Shawn J.
Published in ACS medicinal chemistry letters (13.06.2024)
Published in ACS medicinal chemistry letters (13.06.2024)
Get full text
Journal Article
2-Aminopyridines as Potent and Selective Na v 1.8 Inhibitors Exhibiting Efficacy in a Nonhuman Primate Pain Model
Breslin, Michael J, Schubert, Jeffrey W, Wang, Deping, Huang, Chienjung, Clements, Michelle K, Li, Yuxing, Zhou, Xiaoping, Vardigan, Joshua D, Kraus, Richard L, Santarelli, Vincent P, Uslaner, Jason M, Coleman, Paul J, Stachel, Shawn J
Published in ACS medicinal chemistry letters (13.06.2024)
Published in ACS medicinal chemistry letters (13.06.2024)
Get full text
Journal Article
A Cation-π Interaction Discriminates among Sodium Channels That Are Either Sensitive or Resistant to Tetrodotoxin Block
Santarelli, Vincent P., Eastwood, Amy L., Dougherty, Dennis A., Horn, Richard, Ahern, Christopher A.
Published in The Journal of biological chemistry (16.03.2007)
Published in The Journal of biological chemistry (16.03.2007)
Get full text
Journal Article
TASK-3 as a potential antidepressant target
Gotter, Anthony L, Santarelli, Vincent P, Doran, Scott M, Tannenbaum, Pamela L, Kraus, Richard L, Rosahl, Thomas W, Meziane, Hamid, Montial, Marina, Reiss, Duane R, Wessner, Keith, McCampbell, Alexander, Stevens, Joanne, Brunner, Joseph I, Fox, Steven V, Uebele, Victor N, Bayliss, Douglas A, Winrow, Christopher J, Renger, John J
Published in Brain research (06.10.2011)
Published in Brain research (06.10.2011)
Get full text
Journal Article
Calcium Block of Single Sodium Channels: Role of a Pore-Lining Aromatic Residue
Santarelli, Vincent P., Eastwood, Amy L., Dougherty, Dennis A., Ahern, Christopher A., Horn, Richard
Published in Biophysical journal (01.10.2007)
Published in Biophysical journal (01.10.2007)
Get full text
Journal Article
Quantitative analysis of the high-frequency components of the terminal portion of the body surface QRS in normal subjects and in patients with ventricular tachycardia
Denes, P, Santarelli, P, Hauser, R G, Uretz, E F
Published in Circulation (New York, N.Y.) (01.05.1983)
Published in Circulation (New York, N.Y.) (01.05.1983)
Get full text
Journal Article
Positive Allosteric Interaction of Structurally Diverse T-Type Calcium Channel Antagonists
Uebele, Victor N, Nuss, Cindy E, Fox, Steven V, Garson, Susan L, Cristescu, Razvan, Doran, Scott M, Kraus, Richard L, Santarelli, Vincent P, Li, Yuxing, Barrow, James C, Yang, Zhi-Qiang, Schlegel, Kelly-Ann S, Rittle, Kenneth E, Reger, Thomas S, Bednar, Rodney A, Lemaire, Wei, Mullen, Faith A, Ballard, Jeanine E, Tang, Cuyue, Dai, Ge, McManus, Owen B, Koblan, Kenneth S, Renger, John J
Published in Cell biochemistry and biophysics (01.11.2009)
Published in Cell biochemistry and biophysics (01.11.2009)
Get full text
Journal Article
First human experience with pulmonary vein isolation using a through-the-balloon circumferential ultrasound ablation system for recurrent atrial fibrillation
NATALE, Andrea, PISANO, Ennio, KANAGARATNAM, Logan, TCHOU, Patrick, LESH, Michael, SHEWCHIK, Jeannie, BASH, Dianna, FANELLI, Raffaele, POTENZA, Domenico, SANTARELLI, Pietro, SCHWEIKERT, Robert, WHITE, Richard, SALIBA, Walid
Published in Circulation (New York, N.Y.) (17.10.2000)
Published in Circulation (New York, N.Y.) (17.10.2000)
Get full text
Journal Article
Mediterranean diet and inflammatory response in myocardial infarction survivors
Panagiotakos, Demosthenes B, Dimakopoulou, Konstantina, Katsouyanni, Klea, Bellander, Tom, Grau, Maria, Koenig, Wolfgang, Lanki, Timo, Pistelli, Riccardo, Schneider, Alexandra, Peters, Annette
Published in International journal of epidemiology (01.06.2009)
Published in International journal of epidemiology (01.06.2009)
Get full text
Journal Article
A Cation-Ï Interaction Discriminates among Sodium Channels That Are Either Sensitive or Resistant to Tetrodotoxin Block
Vincent P. Santarelli, Amy L. Eastwood, Dennis A. Dougherty, Richard Horn, Christopher A. Ahern
Published in The Journal of biological chemistry (16.03.2007)
Published in The Journal of biological chemistry (16.03.2007)
Get full text
Journal Article
Effects of subcutaneous recombinant human erythropoietin in patients on continuous ambulatory peritoneal dialysis
Di Paolo, B, Marini, A, Fiederling, B, Di Liberato, L, Santarelli, P, Bucciarelli, S, Stuard, S, Paolantonio, L, Albertazzi, A
Published in Peritoneal dialysis international (1993)
Published in Peritoneal dialysis international (1993)
Get full text
Journal Article
Incidence and pathophysiology of hypertension in continuous ambulatory peritoneal dialysis
DI PAOLO, B, DI LIBERATO, L, FIEDERLING, B, STUARD, S, MARINI, A, BUCCIARELLI, S, SANTOFERRARA, A, SANTARELLI, P, ALBERTAZZI, A
Published in Peritoneal dialysis international (1993)
Published in Peritoneal dialysis international (1993)
Get full text
Conference Proceeding
Journal Article
90 The effects of right ventricular pacing on ventricular synchrony studied by tissue Doppler echocardiography: A prospective study in patients undergoing single/dual chamber pacemaker implantation
Lotrionte, M., Natali, R., Biondi-Zoccai, G., Comerci, G., Savino, M., Natale, A., Loperfido, F., Santarelli, P.
Published in European journal of heart failure. Supplements (01.06.2006)
Published in European journal of heart failure. Supplements (01.06.2006)
Get full text
Journal Article
Circumferential Ultrasound Ablation for Pulmonary Vein Isolation: Analysis of Acute and Chronic Failures
SALIBA, WALID, WILBER, DAVID, PACKER, DOUGLAS, MARROUCHE, NASSIR, SCHWEIKERT, ROBERT, PISANO, ENNIO, SHEWCHIK, JEANNIE, BASH, DIANNA, FANELLI, RAFFAELE, POTENZA, DOMENICO, SANTARELLI, PIETRO, TCHOU, PATRICK, NATALE, ANDREA
Published in Journal of cardiovascular electrophysiology (01.10.2002)
Published in Journal of cardiovascular electrophysiology (01.10.2002)
Get full text
Journal Article