Search Results - "Marle, Sjoerd van" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Metabolism and Disposition of Siponimod, a Novel Selective S1P1/S1P5 Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism

Metabolism and Disposition of Siponimod, a Novel Selective S1P1/S1P5 Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism

by Glaenzel, Ulrike, Jin, Yi, Nufer, Robert, Li, Wenkui, Schroer, Kirsten, Adam-Stitah, Sylvie, van Marle, Sjoerd Peter, Legangneux, Eric, Borell, Hubert, James, Alexander D, Meissner, Axel, Camenisch, Gian, Gardin, Anne
Published in Drug metabolism and disposition (01.07.2018)

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Pharmacokinetic Properties of Mirabegron, a β3 -Adrenoceptor Agonist: Results From Two Phase I, Randomized, Multiple-Dose Studies in Healthy Young and Elderly Men and Women

Pharmacokinetic Properties of Mirabegron, a β3 -Adrenoceptor Agonist: Results From Two Phase I, Randomized, Multiple-Dose Studies in Healthy Young and Elderly Men and Women

by Krauwinkel, Walter, MSc, van Dijk, Jan, BSc, Schaddelee, Marloes, PhD, Eltink, Charlotte, MSc, Meijer, John, MSc, Strabach, Grégory, MD, van Marle, Sjoerd, MD, Kerbusch, Virginie, PhD, van Gelderen, Marcel, PhD
Published in Clinical therapeutics (01.10.2012)

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Safety and Pharmacokinetics of Intravenous and Oral Fosmanogepix, a First-in-Class Antifungal Agent, in Healthy Volunteers

Safety and Pharmacokinetics of Intravenous and Oral Fosmanogepix, a First-in-Class Antifungal Agent, in Healthy Volunteers

by Hodges, Michael R, Ople, Eric, Wedel, Pamela, Shaw, Karen J, Jakate, Abhijeet, Kramer, William G, Marle, Sjoerd van, van Hoogdalem, Ewoud-Jan, Tawadrous, Margaret
Published in Antimicrobial agents and chemotherapy (18.04.2023)

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Comparison of the injection‐site experience of the starting doses with semaglutide and dulaglutide: A randomized, double‐blind trial in healthy subjects

Comparison of the injection‐site experience of the starting doses with semaglutide and dulaglutide: A randomized, double‐blind trial in healthy subjects

by Snitker, Søren, Andersen, Andreas, Berg, Birgitte, van Marle, Sjoerd, Sparre, Thomas
Published in Diabetes, obesity & metabolism (01.06.2021)

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Pharmacokinetics of [14C]ciclesonide after oral and intravenous administration to healthy subjects

Pharmacokinetics of [14C]ciclesonide after oral and intravenous administration to healthy subjects

by NAVE, Ruediger, BETHKE, Thomas D, VAN MARLE, Sjoerd P, ZECH, Karl
Published in Clinical pharmacokinetics (2004)

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Comparison of the injection‐site experience of semaglutide in a single‐dose and a multidose pen‐injector

Comparison of the injection‐site experience of semaglutide in a single‐dose and a multidose pen‐injector

by Snitker, Søren, Andersen, Andreas, Lindskov, Pernille Skøtt, Marle, Sjoerd, Sode, Birgitte Fischer, Sparre, Thomas
Published in Diabetes, obesity & metabolism (01.08.2022)

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EDP‐297: A novel, farnesoid X receptor agonist—Results of a phase I study in healthy subjects

EDP‐297: A novel, farnesoid X receptor agonist—Results of a phase I study in healthy subjects

by Marotta, Christine, Ahmad, Alaa, Luo, Ed, Oosterhaven, Jart, Marle, Sjoerd, Adda, Nathalie
Published in Clinical and translational science (01.02.2023)

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Metabolism and Excretion of Intravenous, Radio-Labeled Amisulpride in Healthy, Adult Volunteers

Metabolism and Excretion of Intravenous, Radio-Labeled Amisulpride in Healthy, Adult Volunteers

by Fox, Gabriel M, Roffel, Ad F, Hartstra, Jan, Bussian, Linda A, van Marle, Sjoerd P
Published in Clinical pharmacology: advances and applications (01.12.2019)

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Hypertensive crisis-induced electrocardiographic changes: a case series

Hypertensive crisis-induced electrocardiographic changes: a case series

by Farha, Khalid Abou, van Vliet, André, van Marle, Sjoerd, Vrijlandt, Patrick, Westenbrink, Daan
Published in Journal of medical case reports (20.08.2009)

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EDP-297: a novel, highly potent, farnesoid X receptor agonist, results of a phase 1 study in healthy subjects

EDP-297: a novel, highly potent, farnesoid X receptor agonist, results of a phase 1 study in healthy subjects

by Ahmad, Alaa, Marotta, Christine, Luo, Ed, Oosterhaven, Jart, van Marle, Sjoerd, Adda, Nathalie
Published in Journal of hepatology (01.07.2022)

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Phase 1 drug-drug interaction study to assess the effect of CYP3A4 inhibition and pan-CYP induction on the pharmacokinetics and safety of fosmanogepix in healthy participants

Phase 1 drug-drug interaction study to assess the effect of CYP3A4 inhibition and pan-CYP induction on the pharmacokinetics and safety of fosmanogepix in healthy participants

by Hodges, Michael R, van Marle, Sjoerd, Kramer, William G, Ople, Eric, Tawadrous, Margaret, Jakate, Abhijeet
Published in Antimicrobial agents and chemotherapy (17.05.2024)

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Pharmacokinetics, safety, and tolerability of fosmanogepix IV to oral switch and multiple IV doses in healthy participants

Pharmacokinetics, safety, and tolerability of fosmanogepix IV to oral switch and multiple IV doses in healthy participants

by Hodges, Michael R, Hazel, Susan, Kramer, William G, van Hoogdalem, Ewoud-Jan, van Marle, Sjoerd, Tawadrous, Margaret, Jakate, Abhijeet
Published in Antimicrobial agents and chemotherapy (02.05.2024)

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Metabolism and Disposition of Siponimod, a Novel Selective S1P 1 /S1P 5 Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism

Metabolism and Disposition of Siponimod, a Novel Selective S1P 1 /S1P 5 Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism

by Glaenzel, Ulrike, Jin, Yi, Nufer, Robert, Li, Wenkui, Schroer, Kirsten, Adam-Stitah, Sylvie, Peter van Marle, Sjoerd, Legangneux, Eric, Borell, Hubert, James, Alexander D, Meissner, Axel, Camenisch, Gian, Gardin, Anne
Published in Drug metabolism and disposition (01.07.2018)

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OR23-05 Human Absorption, Metabolism, Excretion, and Absolute Oral Bioavailability of 14C-CRN00808, an Orally Bioavailable, Nonpeptide, Selective, Somatostatin Receptor 2 (sST2) Biased Agonist for the Treatment of Acromegaly

OR23-05 Human Absorption, Metabolism, Excretion, and Absolute Oral Bioavailability of 14C-CRN00808, an Orally Bioavailable, Nonpeptide, Selective, Somatostatin Receptor 2 (sST2) Biased Agonist for the Treatment of Acromegaly

by Madan, Ajay, Luo, Rosa, Cook, Stephen Ferrara, Struthers, Scott, van Marle, Sjoerd, Krasner, Alan
Published in Journal of the Endocrine Society (08.05.2020)

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Absorption, metabolism and excretion of darexaban (YM150), a new direct factor Xa inhibitor in humans

Absorption, metabolism and excretion of darexaban (YM150), a new direct factor Xa inhibitor in humans

by Hashimoto, Tadashi, Suzuki, Katsuhiro, Kihara, Yukie, Iwatsubo, Takafumi, Miyashita, Aiji, Heeringa, Marten, Onkels, Hartmut, Groenendaal, Dorien, Verheggen, Frank, van Marle, Sjoerd, Usui, Takashi
Published in Xenobiotica (01.06.2013)

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Pharmacokinetic Characterization of the Novel Pulmonary Delivery Excipient Fumaryl Diketopiperazine

Pharmacokinetic Characterization of the Novel Pulmonary Delivery Excipient Fumaryl Diketopiperazine

by Potocka, Elizabeth, Cassidy, James P., Haworth, Pamela, Heuman, Douglas, van Marle, Sjoerd, Baughman, Robert A.
Published in Journal of diabetes science and technology (01.09.2010)

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Sugammadex is cleared rapidly and primarily unchanged via renal excretion

Sugammadex is cleared rapidly and primarily unchanged via renal excretion

by Peeters, Pierre, Passier, Paul, Smeets, Jean, Zwiers, Alex, de Zwart, Marcel, van de Wetering-Krebbers, Saskia, van Iersel, Marlou, van Marle, Sjoerd, van den Dobbelsteen, Diels
Published in Biopharmaceutics & drug disposition (01.04.2011)

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Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a randomised study

Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a randomised study

by Cahn, Anthony, Hodgson, Simon, Wilson, Robert, Robertson, Jonathan, Watson, Joanna, Beerahee, Misba, Hughes, Steve C, Young, Graeme, Graves, Rebecca, Hall, David, van Marle, Sjoerd, Solari, Roberto
Published in BMC pharmacology & toxicology (28.02.2013)

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Phase 1 Study to Assess Safety, Tolerability and Pharmacokinetics of Single and Multiple Oral Doses of APX001 and to Investigate the Effect of Food on APX001 Bioavailability

Phase 1 Study to Assess Safety, Tolerability and Pharmacokinetics of Single and Multiple Oral Doses of APX001 and to Investigate the Effect of Food on APX001 Bioavailability

by Hodges, Michael R, Ople, Eric, Shaw, Karen J, Mansbach, Robert, Van Marle, Sjoerd P, Van Hoogdalem, Ewoud-Jan, Kramer, William, Wedel, Pamela
Published in Open forum infectious diseases (01.10.2017)

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First-in-Human Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects

First-in-Human Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects

by Hodges, Michael R, Ople, Eric, Shaw, Karen J, Mansbach, Robert, Van Marle, Sjoerd J, Van Hoogdalem, Ewoud-Jan, Wedel, Pamela, Kramer, William
Published in Open forum infectious diseases (01.10.2017)

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