Safety and survival with GVAX pancreas prime and Listeria Monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer
Le, Dung T, Wang-Gillam, Andrea, Picozzi, Vincent, Greten, Tim F, Crocenzi, Todd, Springett, Gregory, Morse, Michael, Zeh, Herbert, Cohen, Deirdre, Fine, Robert L, Onners, Beth, Uram, Jennifer N, Laheru, Daniel A, Lutz, Eric R, Solt, Sara, Murphy, Aimee Luck, Skoble, Justin, Lemmens, Ed, Grous, John, Dubensky, Jr, Thomas, Brockstedt, Dirk G, Jaffee, Elizabeth M
Published in Journal of clinical oncology (20.04.2015)
Published in Journal of clinical oncology (20.04.2015)
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A first-in-human phase 1, multicenter, open-label study of CB-011, a next-generation CRISPR-genome edited allogeneic anti-BCMA immune-cloaked CAR-T cell therapy, in patients with relapsed/refractory multiple myeloma (CAMMOUFLAGE trial)
Berdeja, Jesus G., Martin, Thomas G., Rossi, Adriana, Essell, James H., Siegel, David Samuel DiCapua, Mailankody, Sham, Saini, Neeraj, Holmes, Houston, Dhakal, Binod, Gasparetto, Cristina J., Parekh, Samir S., Portella, Socorro, Ledergor, Guy, Hammad, Ashley, Davi, Franco, Skoble, Justin, Garner, Elizabeth, Kanner, Steven Brian, Rizvi, Syed, Jagannath, Sundar
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Allogeneic chimeric antigen receptor-T cells with CRISPR-disrupted programmed death-1 checkpoint exhibit enhanced functional fitness
Lau, Elaine, Kwong, George, Fowler, Tristan W., Sun, Bee-Chun, Donohoue, Paul D., Davis, Ryan T., Bryan, Mara, McCawley, Shannon, Clarke, Starlynn C., Williams, Carolyn, Banh, Lynda, Irby, Matthew, Edwards, Leslie, Storlie, Meghan, Kohrs, Bryan, Lilley, Graham W.J., Smith, Stephen C., Gradia, Scott, Fuller, Chris K., Skoble, Justin, Garner, Elizabeth, van Overbeek, Megan, Kanner, Steven B.
Published in Cytotherapy (Oxford, England) (01.07.2023)
Published in Cytotherapy (Oxford, England) (01.07.2023)
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Phase I study of safety and immunogenicity of ADU-623, a live-attenuated Listeria monocytogenes vaccine (Δ actA /Δ inlB ) expressing EGFRvIII and NY-ESO-1, in patients with WHO grade III/IV astrocytomas
Crittenden, Marka, Bahjat, Keith S., Li, Rui, Gore, Pankaj A., Fountain, Chris, Hanson, Bill, Skoble, Justin, Lauer, Peter, Murphy, Aimee, Dubensky, Thomas Walter, Brockstedt, Dirk G., Urba, Walter John
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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A phase 2b, randomized, controlled, multicenter, open-label study of the efficacy and immune response of GVAX pancreas vaccine and CRS-207 compared to chemotherapy or to CRS-207 alone in adults with previously treated metastatic pancreatic adenocarcinoma (ECLIPSE Study)
Le, Dung T., Wang-Gillam, Andrea, Picozzi, Vincent J., Crocenzi, Todd S., Morse, Michael, Zeh, Herbert, Fine, Robert Lance, Murphy, Aimee, Skoble, Justin, Lemmens, Ed, Ferber, Sandy, Rosen, Allan, Grous, John J., Dubensky, Thomas, Brockstedt, Dirk G., Jaffee, Elizabeth M.
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
A phase IIb, randomized, controlled, multicenter, open-label study of the efficacy and immune response of GVAX pancreas vaccine and CRS-207 compared to chemotherapy or to CRS-207 alone in adults with previously treated metastatic pancreatic adenocarcinoma (ECLIPSE Study)
Le, Dung T., Wang-Gillam, Andrea, Picozzi, Vincent J., Crocenzi, Todd S., Morse, Michael, Zeh, Herbert, Fine, Robert Lance, Murphy, Aimee, Skoble, Justin, Lemmens, Ed, Ferber, Sandy, Rosen, Allan, Grous, John J., Dubensky, Thomas, Brockstedt, Dirk G., Lutz, Eric, Jaffee, Elizabeth M.
Published in Journal of clinical oncology (20.01.2015)
Published in Journal of clinical oncology (20.01.2015)
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Journal Article
A phase 2, randomized trial of GVAX pancreas and CRS-207 immunotherapy versus GVAX alone in patients with metastatic pancreatic adenocarcinoma: Updated results
Le, Dung T., Wang-Gillam, Andrea, Picozzi, Jr, Vincent, Greten, Tim F., Crocenzi, Todd S., Springett, Gregory M., Morse, Michael, Zeh, Herbert, Cohen, Deirdre Jill, Fine, Robert Lance, Onners, Beth, Uram, Jennifer N., Laheru, Dan, Murphy, Aimee, Skoble, Justin, Lemmens, Ed, Grous, John J., Dubensky, Thomas, Brockstedt, Dirk G., Jaffee, Elizabeth M.
Published in Journal of clinical oncology (20.01.2014)
Published in Journal of clinical oncology (20.01.2014)
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Journal Article
Interim safety and efficacy analysis of a phase II, randomized study of GVAX pancreas and CRS-207 immunotherapy in patients with metastatic pancreatic cancer
Le, Dung T., Wang-Gillam, Andrea, Picozzi, Vincent J., Greten, Tim F., Crocenzi, Todd S., Springett, Gregory M., Morse, Michael, Zeh, Herbert, Cohen, Deirdre Jill, Fine, Robert Lance, Onners, Beth, Uram, Jennifer N., Murphy, Aimee, Skoble, Justin, Lemmens, Ed, Grous, John J., Dubensky, Thomas, Brockstedt, Dirk G., Jaffee, Elizabeth M.
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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