Search Results - "Oliveira Santos, Jana Sopkova-de" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Synthesis and Structure–Affinity Relationships of Selective High-Affinity 5‑HT4 Receptor Antagonists: Application to the Design of New Potential Single Photon Emission Computed Tomography Tracers

Synthesis and Structure–Affinity Relationships of Selective High-Affinity 5‑HT4 Receptor Antagonists: Application to the Design of New Potential Single Photon Emission Computed Tomography Tracers

by Dubost, Emmanuelle, Dumas, Noé, Fossey, Christine, Magnelli, Rosa, Butt-Gueulle, Sabrina, Ballandonne, Céline, Caignard, Daniel H, Dulin, Fabienne, Sopkova de-Oliveira Santos, Jana, Millet, Philippe, Charnay, Yves, Rault, Sylvain, Cailly, Thomas, Fabis, Frederic
Published in Journal of medicinal chemistry (26.11.2012)

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Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode

Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode

by Hedir, Siham, De Giorgi, Marcella, Fogha, Jade, De Pascale, Martina, Weiswald, Louis-Bastien, Brotin, Emilie, Marekha, Bogdan, Denoyelle, Christophe, Denis, Camille, Suzanne, Peggy, Gautier, Fabien, Juin, Philippe, Ligat, Laetitia, Lopez, Frédéric, Carlier, Ludovic, Legay, Rémi, Bureau, Ronan, Rault, Sylvain, Poulain, Laurent, Oliveira Santos, Jana Sopková-de, Voisin-Chiret, Anne Sophie
Published in European journal of medicinal chemistry (05.11.2018)

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Synthesis of Pyridoclax Analogues: Insight into Their Druggability by Investigating Their Physicochemical Properties and Interactions with Membranes

Synthesis of Pyridoclax Analogues: Insight into Their Druggability by Investigating Their Physicochemical Properties and Interactions with Membranes

by De Pascale, Martina, Iacopetta, Domenico, Since, Marc, Corvaisier, Sophie, Vie, Véronique, Paboeuf, Gilles, Hennequin, Didier, Perato, Serge, De Giorgi, Marcella, Sinicropi, Maria Stefania, Sopkova‐De Oliveira Santos, Jana, Voisin‐Chiret, Anne‐Sophie, Malzert‐Freon, Aurélie
Published in ChemMedChem (07.01.2020)

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Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a “Bio-Oxidizable” Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation

Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a “Bio-Oxidizable” Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation

by Peauger, Ludovic, Azzouz, Rabah, Gembus, Vincent, Ţînţaş, Mihaela-Liliana, Sopková-de Oliveira Santos, Jana, Bohn, Pierre, Papamicaël, Cyril, Levacher, Vincent
Published in Journal of medicinal chemistry (13.07.2017)

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Benzylphenylpyrrolizinones with Anti‐amyloid and Radical Scavenging Effects, Potentially Useful in Alzheimer's Disease Treatment

Benzylphenylpyrrolizinones with Anti‐amyloid and Radical Scavenging Effects, Potentially Useful in Alzheimer's Disease Treatment

by Jourdan, Jean‐Pierre, Since, Marc, El Kihel, Laïla, Lecoutey, Cédric, Corvaisier, Sophie, Legay, Rémi, Sopková‐de Oliveira Santos, Jana, Cresteil, Thierry, Malzert‐Fréon, Aurélie, Rochais, Christophe, Dallemagne, Patrick
Published in ChemMedChem (21.06.2017)

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Discovery of a pocket network on the domain 5 of the TrkB receptor – A potential new target in the quest for the new ligands

Discovery of a pocket network on the domain 5 of the TrkB receptor – A potential new target in the quest for the new ligands

by Antonijevic, Mirjana, Sopkova‐de Oliveira Santos, Jana, Dallemagne, Patrick, Rochais, Christophe
Published in Molecular informatics (01.08.2024)

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Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT4R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride

Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT4R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride

by Rochais, Christophe, Lecoutey, Cédric, Gaven, Florence, Giannoni, Patrizia, Hamidouche, Katia, Hedou, Damien, Dubost, Emmanuelle, Genest, David, Yahiaoui, Samir, Freret, Thomas, Bouet, Valentine, Dauphin, François, Sopkova de Oliveira Santos, Jana, Ballandonne, Céline, Corvaisier, Sophie, Malzert-Fréon, Aurélie, Legay, Remi, Boulouard, Michel, Claeysen, Sylvie, Dallemagne, Patrick
Published in Journal of medicinal chemistry (09.04.2015)

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Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer’s disease

Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer’s disease

by Toublet, François-Xavier, Lalut, Julien, Hatat, Bérénice, Lecoutey, Cédric, Davis, Audrey, Since, Marc, Corvaisier, Sophie, Freret, Thomas, Sopková-de Oliveira Santos, Jana, Claeysen, Sylvie, Boulouard, Michel, Dallemagne, Patrick, Rochais, Christophe
Published in European journal of medicinal chemistry (15.01.2021)

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Novel donepezil-like N-benzylpyridinium salt derivatives as AChE inhibitors and their corresponding dihydropyridine “bio-oxidizable” prodrugs: Synthesis, biological evaluation and structure-activity relationship

Novel donepezil-like N-benzylpyridinium salt derivatives as AChE inhibitors and their corresponding dihydropyridine “bio-oxidizable” prodrugs: Synthesis, biological evaluation and structure-activity relationship

by Azzouz, Rabah, Peauger, Ludovic, Gembus, Vincent, Ţînţaş, Mihaela-Liliana, Sopková-de Oliveira Santos, Jana, Papamicaël, Cyril, Levacher, Vincent
Published in European journal of medicinal chemistry (10.02.2018)

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Design, synthesis and biological evaluation of novel indano- and thiaindano-pyrazoles with potential interest for Alzheimer's disease

Design, synthesis and biological evaluation of novel indano- and thiaindano-pyrazoles with potential interest for Alzheimer's disease

by Genest, David, Rochais, Christophe, Lecoutey, Cédric, Oliveira Santos, Jana Sopkova-de, Ballandonne, Céline, Butt-Gueulle, Sabrina, Legay, Remi, Since, Marc, Dallemagne, Patrick
Published in MedChemComm (01.06.2013)

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Drug Repurposing: Deferasirox Inhibits the Anti-Apoptotic Activity of Mcl-1

Drug Repurposing: Deferasirox Inhibits the Anti-Apoptotic Activity of Mcl-1

by Bourafai-Aziez, Asma, Benabderrahmane, Mohammed, Paysant, Hippolyte, Weiswald, Louis-Bastien, Poulain, Laurent, Carlier, Ludovic, Ravault, Delphine, Jouanne, Marie, Coadou, Gaël, Oulyadi, Hassan, Voisin-Chiret, Anne-Sophie, Sopková-de Oliveira Santos, Jana, Sebban, Muriel
Published in Drug design, development and therapy (01.01.2021)

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Synthesis and biological evaluation of new 5-benzylated 4-oxo-3,4-dihydro-5H-pyridazino[4,5-b]indoles as PI3Kα inhibitors

Synthesis and biological evaluation of new 5-benzylated 4-oxo-3,4-dihydro-5H-pyridazino[4,5-b]indoles as PI3Kα inhibitors

by Bruel, Amélie, Logé, Cédric, Tauzia, Marie-Ludivine de, Ravache, Myriam, Le Guevel, Rémy, Guillouzo, Christiane, Lohier, Jean-François, Oliveira Santos, Jana Sopkova-de, Lozach, Olivier, Meijer, Laurent, Ruchaud, Sandrine, Bénédetti, Hélène, Robert, Jean-Michel
Published in European journal of medicinal chemistry (01.11.2012)

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Hot-Spots of Mcl-1 Protein

Hot-Spots of Mcl-1 Protein

by Denis, Camille, Sopková-de Oliveira Santos, Jana, Bureau, Ronan, Voisin-Chiret, Anne Sophie
Published in Journal of medicinal chemistry (13.02.2020)

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Design, synthesis and preliminary biological evaluation of rivastigmine-INDY hybrids as multitarget ligands against Alzheimer's disease by targeting butyrylcholinesterase and DYRK1A/CLK1 kinases

Design, synthesis and preliminary biological evaluation of rivastigmine-INDY hybrids as multitarget ligands against Alzheimer's disease by targeting butyrylcholinesterase and DYRK1A/CLK1 kinases

by în a, Mihaela-Liliana, Peauger, Ludovic, Barré, Anaïs, Papamicaël, Cyril, Besson, Thierry, Sopkovà-de Oliveira Santos, Jana, Gembus, Vincent, Levacher, Vincent
Published in MedChemComm (20.03.2024)

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Hydrogenative desulphurization of thienopyrrolizinones: An easy and selective access to ( Z)-phenethylidenepyrrolizinones with in vitro cytotoxic activity

Hydrogenative desulphurization of thienopyrrolizinones: An easy and selective access to ( Z)-phenethylidenepyrrolizinones with in vitro cytotoxic activity

by Perri, Vittoria, Rochais, Christophe, Sopkova-de Oliveira Santos, Jana, Legay, Rémi, Cresteil, Thierry, Dallemagne, Patrick, Rault, Sylvain
Published in European journal of medicinal chemistry (01.03.2010)

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Tau protein aggregation: Key features to improve drug discovery screening

Tau protein aggregation: Key features to improve drug discovery screening

by Giovannini, Johanna, Smeralda, Willy, Jouanne, Marie, Sopkova-de Oliveira Santos, Jana, Catto, Marco, Voisin-Chiret, Anne Sophie
Published in Drug discovery today (01.05.2022)

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Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT4R) partial agonist and 5-HT6R antagonist activities, as potential treatment of Alzheimer’s disease

Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT4R) partial agonist and 5-HT6R antagonist activities, as potential treatment of Alzheimer’s disease

by Yahiaoui, Samir, Hamidouche, Katia, Ballandonne, Céline, Davis, Audrey, de Oliveira Santos, Jana Sopkova, Freret, Thomas, Boulouard, Michel, Rochais, Christophe, Dallemagne, Patrick
Published in European journal of medicinal chemistry (04.10.2016)

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Design, Synthesis, Molecular Dynamics Simulation, and Functional Evaluation of a Novel Series of 26RFa Peptide Analogues Containing a Mono- or Polyalkyl Guanidino Arginine Derivative

Design, Synthesis, Molecular Dynamics Simulation, and Functional Evaluation of a Novel Series of 26RFa Peptide Analogues Containing a Mono- or Polyalkyl Guanidino Arginine Derivative

by Alim, Karima, Lefranc, Benjamin, Sopkova-de Oliveira Santos, Jana, Dubessy, Christophe, Picot, Marie, Boutin, Jean A, Vaudry, Hubert, Chartrel, Nicolas, Vaudry, David, Chuquet, Julien, Leprince, Jérôme
Published in Journal of medicinal chemistry (21.11.2018)

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Synthesis and biological evaluation as AChE inhibitors of new indanones and thiaindanones related to donepezil

Synthesis and biological evaluation as AChE inhibitors of new indanones and thiaindanones related to donepezil

by Omran, Ziad, Cailly, Thomas, Lescot, Elodie, Santos, Jana Sopkova-de Oliveira, Agondanou, Jean-Hugues, Lisowski, Vincent, Fabis, Frédéric, Godard, Anne-Marie, Stiebing, Silvia, Le Flem, Guillaume, Boulouard, Michel, Dauphin, François, Dallemagne, Patrick, Rault, Sylvain
Published in European journal of medicinal chemistry (01.12.2005)

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Novel benzylidenephenylpyrrolizinones with pleiotropic activities potentially useful in Alzheimer's disease treatment

Novel benzylidenephenylpyrrolizinones with pleiotropic activities potentially useful in Alzheimer's disease treatment

by Jourdan, Jean-Pierre, Since, Marc, El Kihel, Laïla, Lecoutey, Cédric, Corvaisier, Sophie, Legay, Rémi, Sopkova-de Oliveira Santos, Jana, Cresteil, Thierry, Malzert-Fréon, Aurélie, Rochais, Christophe, Dallemagne, Patrick
Published in European journal of medicinal chemistry (23.05.2016)

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