Computationally Driven Structure Optimization, Synthesis, and Biological Evaluation of Imidazole-Based Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Inhibitors
Lammi, Carmen, Sgrignani, Jacopo, Arnoldi, Anna, Lesma, Giordano, Spatti, Claudia, Silvani, Alessandra, Grazioso, Giovanni
Published in Journal of medicinal chemistry (11.07.2019)
Published in Journal of medicinal chemistry (11.07.2019)
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Journal Article
Phytosterol and γ‑Oryzanol Conjugates: Synthesis and Evaluation of their Antioxidant, Antiproliferative, and Anticholesterol Activities
Lesma, Giordano, Luraghi, Andrea, Bavaro, Teodora, Bortolozzi, Roberta, Rainoldi, Giulia, Roda, Gabriella, Viola, Giampietro, Ubiali, Daniela, Silvani, Alessandra
Published in Journal of natural products (Washington, D.C.) (26.10.2018)
Published in Journal of natural products (Washington, D.C.) (26.10.2018)
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Journal Article
Sequential Multicomponent Strategy for the Diastereoselective Synthesis of Densely Functionalized Spirooxindole-Fused Thiazolidines
Rainoldi, Giulia, Begnini, Fabio, de Munnik, Mariska, Lo Presti, Leonardo, Vande Velde, Christophe M. L, Orru, Romano, Lesma, Giordano, Ruijter, Eelco, Silvani, Alessandra
Published in ACS combinatorial science (12.02.2018)
Published in ACS combinatorial science (12.02.2018)
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Journal Article
Multicomponent Synthesis and Biological Evaluation of a Piperazine-Based Dopamine Receptor Ligand Library
Stucchi, Mattia, Gmeiner, Peter, Huebner, Harald, Rainoldi, Giulia, Sacchetti, Alessandro, Silvani, Alessandra, Lesma, Giordano
Published in ACS medicinal chemistry letters (13.08.2015)
Published in ACS medicinal chemistry letters (13.08.2015)
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Journal Article
Heteronanoparticles by Self-Assembly of Ecdysteroid and Doxorubicin Conjugates To Overcome Cancer Resistance
Fumagalli, Gaia, Giorgi, Giulia, Vágvölgyi, Máté, Colombo, Eleonora, Christodoulou, Michael S, Collico, Veronica, Prosperi, Davide, Dosio, Franco, Hunyadi, Attila, Montopoli, Monica, Hyeraci, Mariafrancesca, Silvani, Alessandra, Lesma, Giordano, Via, Lisa Dalla, Passarella, Daniele
Published in ACS medicinal chemistry letters (10.05.2018)
Published in ACS medicinal chemistry letters (10.05.2018)
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Journal Article
Structural and Biological Exploration of Phe(3)-Phe(4)-Modified Endomorphin-2 Peptidomimetics
Lesma, Giordano, Salvadori, Severo, Airaghi, Francesco, Murray, Thomas F., Recca, Teresa, Sacchetti, Alessandro, Balboni, Gianfranco, Silvani, Alessandra
Published in ACS medicinal chemistry letters (08.08.2013)
Published in ACS medicinal chemistry letters (08.08.2013)
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Journal Article
Structural and Biological Exploration of Phe3–Phe4‑Modified Endomorphin‑2 Peptidomimetics
Lesma, Giordano, Salvadori, Severo, Airaghi, Francesco, Murray, Thomas F, Recca, Teresa, Sacchetti, Alessandro, Balboni, Gianfranco, Silvani, Alessandra
Published in ACS medicinal chemistry letters (08.08.2013)
Published in ACS medicinal chemistry letters (08.08.2013)
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Journal Article
Structural and Biological Exploration of Phe 3 –Phe 4 -Modified Endomorphin-2 Peptidomimetics
Lesma, Giordano, Salvadori, Severo, Airaghi, Francesco, Murray, Thomas F., Recca, Teresa, Sacchetti, Alessandro, Balboni, Gianfranco, Silvani, Alessandra
Published in ACS medicinal chemistry letters (08.08.2013)
Published in ACS medicinal chemistry letters (08.08.2013)
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Journal Article
Bruno Danieli (1939–2014)
Passarella, Daniele, Lesma, Giordano, Silvani, Alessandra, Riva, Sergio
Published in Fitoterapia (01.03.2016)
Published in Fitoterapia (01.03.2016)
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Journal Article
Microwave-assisted, solid-phase synthesis of a chiral 1,2,3,4-tetrahydro-quinoline library
Lesma, Giordano, Danieli, Bruno, Lodroni, Francesco, Passarella, Daniele, Sacchetti, Alessandro, Silvani, Alessandra
Published in Combinatorial chemistry & high throughput screening (01.11.2006)
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Published in Combinatorial chemistry & high throughput screening (01.11.2006)
Journal Article
Combinatorial Solid-Phase Synthesis of 6-Hydroxy-1,2,3,4-tetrahydro-β-carbolines from l-5-Hydroxytryptophan
Danieli, Bruno, Giovanelli, Paola, Lesma, Giordano, Passarella, Daniele, Sacchetti, Alessandro, Silvani, Alessandra
Published in Journal of combinatorial chemistry (01.05.2005)
Published in Journal of combinatorial chemistry (01.05.2005)
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Journal Article