Targeting the PAC1 Receptor for Neurological and Metabolic Disorders
Liao, Chenyi, de Molliens, Mathilde P, Schneebeli, Severin T, Brewer, Matthias, Song, Gaojie, Chatenet, David, Braas, Karen M, May, Victor, Li, Jianing
Published in Current topics in medicinal chemistry (01.01.2019)
Published in Current topics in medicinal chemistry (01.01.2019)
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Characterizations of a synthetic pituitary adenylate cyclase-activating polypeptide analog displaying potent neuroprotective activity and reduced in vivo cardiovascular side effects in a Parkinson's disease model
Lamine, Asma, Létourneau, Myriam, Doan, Ngoc Duc, Maucotel, Julie, Couvineau, Alain, Vaudry, Hubert, Chatenet, David, Vaudry, David, Fournier, Alain
Published in Neuropharmacology (01.09.2016)
Published in Neuropharmacology (01.09.2016)
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Development and Pharmacological Characterization of Conformationally Constrained Urotensin II-Related Peptide Agonists
Chatenet, David, Folch, Benjamin, Feytens, Debby, Létourneau, Myriam, Tourwé, Dirk, Doucet, Nicolas, Fournier, Alain
Published in Journal of medicinal chemistry (12.12.2013)
Published in Journal of medicinal chemistry (12.12.2013)
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Behavioral effects of urotensin-II centrally administered in mice
DO-REGO, Jean-Claude, CHATENET, David, ORTA, Marie-Hélène, NAUDIN, Bertrand, LE CUDENNEC, Camille, LEPRINCE, Jérome, SCALBERT, Elizabeth, VAUDRY, Hubert, COSTENTIN, Jean
Published in Psychopharmacologia (01.11.2005)
Published in Psychopharmacologia (01.11.2005)
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Towards Targeting the Urotensinergic System: Overview and Challenges
Nassour, Hassan, Iddir, Mustapha, Chatenet, David
Published in Trends in pharmacological sciences (Regular ed.) (01.10.2019)
Published in Trends in pharmacological sciences (Regular ed.) (01.10.2019)
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Expanding Structure–Activity Relationships of Human Urotensin II Peptide Analogues: A Proposed Key Role of the N‑Terminal Region for Novel Urotensin II Receptor Modulators
Merlino, Francesco, Secondo, Agnese, Mitidieri, Emma, Sorrentino, Raffaella, Bellavita, Rosa, Grasso, Nicola, Chatenet, David, Pannaccione, Anna, Grieco, Paolo, d’Emmanuele di Villa Bianca, Roberta, Carotenuto, Alfonso
Published in Journal of medicinal chemistry (22.08.2024)
Published in Journal of medicinal chemistry (22.08.2024)
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Urotensin II Receptor Modulation with 1,3,4-Benzotriazepin-2-one Tetrapeptide Mimics
Wei, Xiaozheng, Diarra, Sitan, Douchez, Antoine, Cunico Dallagnol, Juliana C, Hébert, Terence E., Chatenet, David, Lubell, William D.
Published in Journal of medicinal chemistry (26.10.2023)
Published in Journal of medicinal chemistry (26.10.2023)
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De Novo Conception of Small Molecule Modulators Based on Endogenous Peptide Ligands: Pyrrolodiazepin-2-one γ‑Turn Mimics That Differentially Modulate Urotensin II Receptor-Mediated Vasoconstriction ex Vivo
Dufour-Gallant, Julien, Chatenet, David, Lubell, William D
Published in Journal of medicinal chemistry (11.06.2015)
Published in Journal of medicinal chemistry (11.06.2015)
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International Union of Basic and Clinical Pharmacology. XCII. Urotensin II, urotensin II-related peptide, and their receptor: from structure to function
Vaudry, Hubert, Leprince, Jérôme, Chatenet, David, Fournier, Alain, Lambert, David G, Le Mével, Jean-Claude, Ohlstein, Eliot H, Schwertani, Adel, Tostivint, Hervé, Vaudry, David
Published in Pharmacological reviews (2015)
Published in Pharmacological reviews (2015)
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Insight into the role of urotensin II-related peptide tyrosine residue in UT activation
Billard, Etienne, Létourneau, Myriam, Hébert, Terence E., Chatenet, David
Published in Biochemical pharmacology (15.11.2017)
Published in Biochemical pharmacology (15.11.2017)
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Design, Synthesis, and Biological Assessment of Biased Allosteric Modulation of the Urotensin II Receptor Using Achiral 1,3,4-Benzotriazepin-2-one Turn Mimics
Douchez, Antoine, Billard, Etienne, Hébert, Terence E., Chatenet, David, Lubell, William D.
Published in Journal of medicinal chemistry (14.12.2017)
Published in Journal of medicinal chemistry (14.12.2017)
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Urotensin II(4–11) Azasulfuryl Peptides: Synthesis and Biological Activity
Merlino, Francesco, Yousif, Ali M, Billard, Étienne, Dufour-Gallant, Julien, Turcotte, Stéphane, Grieco, Paolo, Chatenet, David, Lubell, William D
Published in Journal of medicinal chemistry (26.05.2016)
Published in Journal of medicinal chemistry (26.05.2016)
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New insights about the peculiar role of the 28–38 C-terminal segment and some selected residues in PACAP for signaling and neuroprotection
Poujol de Molliens, Mathilde, Létourneau, Myriam, Devost, Dominic, Hébert, Terence E., Fournier, Alain, Chatenet, David
Published in Biochemical pharmacology (01.08.2018)
Published in Biochemical pharmacology (01.08.2018)
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Functional Selectivity Revealed by N‑Methylation Scanning of Human Urotensin II and Related Peptides
Merlino, Francesco, Billard, Étienne, Yousif, Ali M, Di Maro, Salvatore, Brancaccio, Diego, Abate, Luigi, Carotenuto, Alfonso, Bellavita, Rosa, d’Emmanuele di Villa Bianca, Roberta, Santicioli, Paolo, Marinelli, Luciana, Novellino, Ettore, Hébert, Terence E, Lubell, William D, Chatenet, David, Grieco, Paolo
Published in Journal of medicinal chemistry (14.02.2019)
Published in Journal of medicinal chemistry (14.02.2019)
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Urocontrin, a novel UT receptor ligand with a unique pharmacological profile
Chatenet, David, Nguyen, Quang-Trinh, Létourneau, Myriam, Dupuis, Jocelyn, Fournier, Alain
Published in Biochemical pharmacology (01.03.2012)
Published in Biochemical pharmacology (01.03.2012)
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Design and in vitro characterization of PAC1/VPAC1-selective agonists with potent neuroprotective effects
Doan, Ngoc-Duc, Bourgault, Steve, Dejda, Agnieszka, Létourneau, Myriam, Detheux, Michel, Vaudry, David, Vaudry, Hubert, Chatenet, David, Fournier, Alain
Published in Biochemical pharmacology (15.02.2011)
Published in Biochemical pharmacology (15.02.2011)
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