Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO)
Hu, Carol H., Neissel Valente, Meriah W., Halpern, O. Scott, Jusuf, Sutjano, Khan, Javed A., Locke, Gregory A., Duke, Gerald J., Liu, Xiaoqin, Duclos, Franck J., Wexler, Ruth R., Kick, Ellen K., Smallheer, Joanne M.
Published in Bioorganic & medicinal chemistry letters (15.06.2021)
Published in Bioorganic & medicinal chemistry letters (15.06.2021)
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Journal Article
Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors
Hu, Carol H., Wang, Tammy C., Qiao, Jennifer X., Haque, Lauren, Chen, Alice Y.A., Taylor, David S., Ying, Xiaohong, Onorato, Joelle M., Galella, Michael, Shen, Hong, Huang, Christine S., Toussaint, Nathalie, Li, Yi-Xin, Abell, Lynn, Adam, Leonard P., Gordon, David, Wexler, Ruth R., Finlay, Heather J.
Published in Bioorganic & medicinal chemistry letters (15.12.2018)
Published in Bioorganic & medicinal chemistry letters (15.12.2018)
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Journal Article
2-Amino-1,3,4-thiadiazoles in the 7-hydroxy-N-neopentyl spiropiperidine indolinyl series as potent P2Y1 receptor antagonists
Hu, Carol H., Qiao, Jennifer X., Han, Ying, Wang, Tammy C., Hua, Ji, Price, Laura A., Wu, Qimin, Shen, Hong, Huang, Christine S., Rehfuss, Robert, Wexler, Ruth R., Lam, Patrick Y.S.
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
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Journal Article
2-Amino-1,3,4-thiadiazoles in the 7-hydroxy-N-neopentyl spiropiperidine indolinyl series as potent P2Y(1) receptor antagonists
Hu, Carol H., Qiao, Jennifer X., Han, Ying, Wang, Tammy C., Hua, Ji, Price, Laura A., Wu, Qimin, Shen, Hong, Huang, Christine S., Rehfuss, Robert, Wexler, Ruth R., Lam, Patrick Y. S.
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
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Journal Article
2-Amino-1,3,4-thiadiazoles in the 7-hydroxy-N-neopentyl spiropiperidine indolinyl series as potent P2Y sub(1) receptor antagonists
Hu, Carol H, Qiao, Jennifer X, Han, Ying, Wang, Tammy C, Hua, Ji, Price, Laura A, Wu, Qimin, Shen, Hong, Huang, Christine S, Rehfuss, Robert, Wexler, Ruth R, Lam, Patrick YS
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
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Journal Article
Clostridium Difficile Colonization and Disease in Patients Undergoing Hematopoietic Stem Cell Transplantation
Bruminhent, Jackrapong, Wang, Zi-Xuan, Hu, Carol, Wagner, John, Sunday, Richard, Bobik, Brent, Hegarty, Sarah, Keith, Scott, Alpdogan, Seyfettin, Carabasi, Matthew, Filicko-O’Hara, Joanne, Flomenberg, Neal, Kasner, Margaret, Outschoorn, Ubaldo Martinez, Weiss, Mark, Flomenberg, Phyllis
Published in Biology of blood and marrow transplantation (01.09.2014)
Published in Biology of blood and marrow transplantation (01.09.2014)
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Journal Article
Triazolopyridine inhibitors of myeloperoxidase
Shaw, Scott A, Vokits, Benjamin P, Smallheer, Joanne M, Hu, Carol Hui, Valente, Meriah Neissel, Halpern, Oz Scott
Year of Publication 13.07.2021
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Year of Publication 13.07.2021
Patent
Triazolopyridine inhibitors of myeloperoxidase
Shaw, Scott A, Kick, Ellen K, Smallheer, Joanne M, Hu, Carol Hui, Halpern, Oz Scott
Year of Publication 10.09.2019
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Year of Publication 10.09.2019
Patent
Macrocyclic inhibitors of myeloperoxidase
Kick, Ellen K, Jusuf, Sutjano, Smallheer, Joanne M, Hu, Carol Hui, Valente, Meriah Neissel, Halpern, Oz Scott
Year of Publication 03.03.2020
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Year of Publication 03.03.2020
Patent
TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE
Shaw, Scott A, Kick, Ellen K, Smallheer, Joanne M, Hu, Carol Hui, Halpern, Oz Scott
Year of Publication 24.01.2019
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Year of Publication 24.01.2019
Patent
MACROCYCLIC INHIBITORS OF MYELOPEROXIDASE
Kick, Ellen K, Jusuf, Sutjano, Smallheer, Joanne M, Hu, Carol Hui, Valente, Meriah Neissel, Halpern, Oz Scott
Year of Publication 13.06.2019
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Year of Publication 13.06.2019
Patent
Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors
Lloyd John, Qiao Jennifer X, Pi Zulan, Jiang Ji, Finlay Heather, Neels James, Hu Carol Hui, Tora George O, Friends Todd J, Hangeland Jon J
Year of Publication 15.11.2016
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Year of Publication 15.11.2016
Patent
7-hydroxy-spiropipiperidine indolinyl antagonists of P2Y1 receptor
Thibeault Carl, Lam Patrick Y. S, Wang Tammy C, Clark Charles G, Qiao Jennifer X, Yang Wu, Jeon Yoon, DeLucca Indawati, Wang Yufeng, Hu Carol Hui
Year of Publication 30.08.2016
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Year of Publication 30.08.2016
Patent