Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality
Beauparlant, David, Rusert, Peter, Magnus, Carsten, Kadelka, Claus, Weber, Jacqueline, Uhr, Therese, Zagordi, Osvaldo, Oberle, Corinna, Duenas-Decamp, Maria J, Clapham, Paul R, Metzner, Karin J, Günthard, Huldrych F, Trkola, Alexandra
Published in PLoS pathogens (06.03.2017)
Published in PLoS pathogens (06.03.2017)
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Ultradeep single-molecule real-time sequencing of HIV envelope reveals complete compartmentalization of highly macrophage-tropic R5 proviral variants in brain and CXCR4-using variants in immune and peripheral tissues
Brese, Robin L., Gonzalez-Perez, Maria Paz, Koch, Matthew, O’Connell, Olivia, Luzuriaga, Katherine, Somasundaran, Mohan, Clapham, Paul R., Dollar, James Jarad, Nolan, David J, Rose, Rebecca, Lamers, Susanna L.
Published in Journal of neurovirology (01.08.2018)
Published in Journal of neurovirology (01.08.2018)
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Stromal down-regulation of macrophage CD4/CCR5 expression and NF-κB activation mediates HIV-1 non-permissiveness in intestinal macrophages
Shen, Ruizhong, Meng, Gang, Ochsenbauer, Christina, Clapham, Paul R, Grams, Jayleen, Novak, Lea, Kappes, John C, Smythies, Lesley E, Smith, Phillip D
Published in PLoS pathogens (01.05.2011)
Published in PLoS pathogens (01.05.2011)
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KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells
Stine, Johnny T., Wood, Christi, Hill, Mark, Epp, Angela, Raport, Carol J., Schweickart, Vicki L., Endo, Yoshio, Sasaki, Takuma, Simmons, Graham, Boshoff, Chris, Clapham, Paul, Chang, Yuan, Moore, Patrick, Gray, Patrick W., Chantry, David
Published in Blood (15.02.2000)
Published in Blood (15.02.2000)
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CD4-dependent and CD4-independent HIV-2: consequences for neutralization
THOMAS, Elaine R, SHOTTON, Christine, WEISS, Robin A, CLAPHAM, Paul R, MCKNIGHT, Aine
Published in AIDS (London) (14.02.2003)
Published in AIDS (London) (14.02.2003)
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Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity
Mack, M, Luckow, B, Nelson, P J, Cihak, J, Simmons, G, Clapham, P R, Signoret, N, Marsh, M, Stangassinger, M, Borlat, F, Wells, T N, Schlöndorff, D, Proudfoot, A E
Published in The Journal of experimental medicine (20.04.1998)
Published in The Journal of experimental medicine (20.04.1998)
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Inhibition of CCR5-mediated infection by diverse R5 and R5X4 HIV and SIV isolates using novel small molecule inhibitors of CCR5: Effects of viral diversity, target cell and receptor density
Willey, Samantha, Peters, Paul J., Sullivan, W. Matthew, Dorr, Patrick, Perros, Manos, Clapham, Paul R.
Published in Antiviral research (01.11.2005)
Published in Antiviral research (01.11.2005)
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Is CD4 Sufficient for HIV Entry? Cell Surface Molecules Involved in HIV Infection
Clapham, Paul, McKnight, Aine, Simmons, Graham, Weiss, Robin
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29.10.1993)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29.10.1993)
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Conference Proceeding
Evidence for a post-entry barrier to R5 HIV-1 infection of CD4 memory T cells
VYAKARNAM, Annapurna, EYESON, Josiah, CLAPHAM, Paul, TEO, Ian, ZUCKERMAN, Mark, BABAAHMADY, Kaboutar, SCHUITEMAKER, Hanneke, SHAUNAK, Sunil, ROSTRON, Timothy, ROWLAND-JONES, Sarah, SIMMONS, Graham
Published in AIDS (London) (07.09.2001)
Published in AIDS (London) (07.09.2001)
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The CD4 lymphocyte glycoprotein in health and disease - Is CD4 sufficient for HIV entry? Cell surface molecules involved in HIV infection
Clapham, Paul, McKnight, Aine, Simmons, Graham, Weiss, Robin
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29.10.1993)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29.10.1993)
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Human T-cell leukemia virus type I: induction of syncytia and inhibition by patients' sera
Nagy, K, Clapham, P, Cheingsong-Popov, R, Weiss, R A
Published in International journal of cancer (15.09.1983)
Published in International journal of cancer (15.09.1983)
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The human and simian immunodeficiency viruses HIV-1, HIV-2 and SIV interact with similar epitopes on their cellular receptor, the CD4 molecule
Sattentau, Q J, Clapham, P R, Weiss, R A, Beverley, P C, Montagnier, L, Alhalabi, M F, Gluckmann, J C, Klatzmann, D
Published in AIDS (London) (01.04.1988)
Published in AIDS (London) (01.04.1988)
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Coreceptor ligand inhibition of fetal brain cell infection by HIV type 1
Hibbitts, S, Reeves, J D, Simmons, G, Gray, P W, Epstein, L G, Schols, D, de Clercq, E, Wells, T N, Proudfoot, A E, Clapham, P R
Published in AIDS research and human retroviruses (20.07.1999)
Published in AIDS research and human retroviruses (20.07.1999)
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