Regulation of cell survival by lipid phosphate phosphatases involves the modulation of intracellular phosphatidic acid and sphingosine 1-phosphate pools
Long, Jaclyn, Darroch, Peter, Wan, Kah Fei, Kong, Kok Choi, Ktistakis, Nicholas, Pyne, Nigel J, Pyne, Susan
Published in Biochemical journal (01.10.2005)
Published in Biochemical journal (01.10.2005)
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Journal Article
Synthesis of a rhodanine-based compound library targeting Bcl-XL and Mcl-1
Bernardo, Paul H., Sivaraman, Thirunavukkarasu, Wan, Kah-Fei, Xu, Jin, Krishnamoorthy, Janarthanan, Song, Chun Meng, Tian, Liming, Chin, Jasmine S. F., Lim, Diane S. W., Mok, Henry Y. K., Yu, Victor C., Tong, Joo Chuan, Chai, Christina L. L.
Published in Pure and applied chemistry (05.02.2011)
Published in Pure and applied chemistry (05.02.2011)
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Journal Article
Structure-Activity Relationship Studies of Phenanthridine-Based Bcl-X-L Inhibitors
Bernardo, Paul H., Wan, Kah-Fei, Sivaraman, Thirunavukkarasu, Xu, Jin, Moore, Felicity K., Hung, Alvin W., Mok, Henry Y. K., Yu, Victor C., Chai, Christina L. L.
Published in Journal of medicinal chemistry (13.11.2008)
Published in Journal of medicinal chemistry (13.11.2008)
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Journal Article
Structural Insights into the Design of Small Molecule Inhibitors That Selectively Antagonize Mcl-1
Bernardo, Paul H, Sivaraman, Thirunavukkarasu, Wan, Kah-Fei, Xu, Jin, Krishnamoorthy, Janarthanan, Song, Chun Meng, Tian, Liming, Chin, Jasmine S. F, Lim, Diane S. W, Mok, Henry Y. K, Yu, Victor C, Tong, Joo Chuan, Chai, Christina L. L
Published in Journal of medicinal chemistry (11.03.2010)
Published in Journal of medicinal chemistry (11.03.2010)
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Journal Article
Identifying initiation and elongation inhibitors of dengue virus RNA polymerase in a high-throughput lead-finding campaign
Smith, Thomas M, Lim, Siew Pheng, Yue, Kimberley, Busby, Scott A, Arora, Rishi, Seh, Cheah Chen, Wright, S Kirk, Nutiu, Razvan, Niyomrattanakit, Pornwaratt, Wan, Kah Fei, Beer, David, Shi, Pei-Yong, Benson, Timothy E
Published in Journal of biomolecular screening (01.01.2015)
Published in Journal of biomolecular screening (01.01.2015)
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Journal Article
Interaction of kendomycin and semi-synthetic analogues with the anti-apoptotic protein Bcl-xl
Janssen, Christian O., Lim, Stephanie, Lo, Ee Peng, Wan, Kah Fei, Yu, Victor C., Lee, May Ann, Ng, Siew Bee, Everett, Martin J., Buss, Antony D., Lane, David P., Boyce, Rustum S.
Published in Bioorganic & medicinal chemistry (01.11.2008)
Published in Bioorganic & medicinal chemistry (01.11.2008)
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Journal Article
ALPPL2 및/또는 ALPP에 대한 항원-결합 분자 및 그의 용도
TAN BOON OOI PATRICK, NG JIAN DUAN JOHNATHAN, WAN KAH FEI, YAP THAI LEONG, LEE SHUET THENG, WANG CHENG I, SUN WILLIAM, WANG HUAJING, HUANG CHING WEN, HONG SHIN YEE
Year of Publication 17.10.2022
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Year of Publication 17.10.2022
Patent
Structure−Activity Relationship Studies of Phenanthridine-Based Bcl-XL Inhibitors
Bernardo, Paul H, Wan, Kah-Fei, Sivaraman, Thirunavukkarasu, Xu, Jin, Moore, Felicity K, Hung, Alvin W, Mok, Henry Y. K, Yu, Victor C, Chai, Christina L. L
Published in Journal of medicinal chemistry (13.11.2008)
Published in Journal of medicinal chemistry (13.11.2008)
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Journal Article
Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit
Kounde, Cyrille S., Yeo, Hui-Quan, Wang, Qing-Yin, Wan, Kah Fei, Dong, Hongping, Karuna, Ratna, Dix, Ina, Wagner, Trixie, Zou, Bin, Simon, Oliver, Bonamy, Ghislain M.C., Yeung, Bryan K.S., Yokokawa, Fumiaki
Published in Bioorganic & medicinal chemistry letters (15.03.2017)
Published in Bioorganic & medicinal chemistry letters (15.03.2017)
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Journal Article
Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft
Zhang, Yong-Hong, Bhunia, Anirban, Wan, Kah Fei, Lee, Mei Chin, Chan, Shing-Leng, Yu, Victor C-K, Mok, Yu-Keung
Published in Journal of molecular biology (01.12.2006)
Published in Journal of molecular biology (01.12.2006)
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Journal Article
The inhibitory gamma subunit of the type 6 retinal cGMP phosphodiesterase functions to link c-Src and G-protein-coupled receptor kinase 2 in a signaling unit that regulates p42/p44 mitogen-activated protein kinase by epidermal growth factor
Wan, Kah Fei, Sambi, Balwinder S, Tate, Rothwelle, Waters, Catherine, Pyne, Nigel J
Published in The Journal of biological chemistry (16.05.2003)
Published in The Journal of biological chemistry (16.05.2003)
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Journal Article
The Inhibitory γ Subunit of the Type 6 Retinal cGMP Phosphodiesterase Functions to Link c-Src and G-protein-coupled Receptor Kinase 2 in a Signaling Unit That Regulates p42/p44 Mitogen-activated Protein Kinase by Epidermal Growth Factor
Kah Fei Wan, Balwinder S. Sambi, Rothwelle Tate, Catherine Waters, Nigel J. Pyne
Published in The Journal of biological chemistry (16.05.2003)
Published in The Journal of biological chemistry (16.05.2003)
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Journal Article
The Inhibitory γ Subunit of the Type 6 Retinal Cyclic Guanosine Monophosphate Phosphodiesterase Is a Novel Intermediate Regulating p42/p44 Mitogen-activated Protein Kinase Signaling in Human Embryonic Kidney 293 Cells
Wan, Kah Fei, Sambi, Balwinder S., Frame, Mhairi, Tate, Rothwelle, Pyne, Nigel J.
Published in The Journal of biological chemistry (12.10.2001)
Published in The Journal of biological chemistry (12.10.2001)
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Journal Article
The Inhibitory γ Subunit of the Type 6 Retinal Cyclic Guanosine Monophosphate Phosphodiesterase Is a Novel Intermediate Regulating p42/p44 Mitogen-activated Protein Kinase Signaling in Human Embryonic Kidney 293 Cells
Kah Fei Wan, Balwinder S. Sambi, Mhairi Frame, Rothwelle Tate, Nigel J. Pyne
Published in The Journal of biological chemistry (12.10.2001)
Published in The Journal of biological chemistry (12.10.2001)
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Journal Article