Search Results - "Thomas WOLTERING" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors

Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors

by Haider, Ahmed, Gobbi, Luca, Kretz, Julian, Ullmer, Christoph, Brink, Andreas, Honer, Michael, Woltering, Thomas J, Muri, Dieter, Iding, Hans, Bürkler, Markus, Binder, Martin, Bartelmus, Christian, Knuesel, Irene, Pacher, Pal, Herde, Adrienne Müller, Spinelli, Francesco, Ahmed, Hazem, Atz, Kenneth, Keller, Claudia, Weber, Markus, Schibli, Roger, Mu, Linjing, Grether, Uwe, Ametamey, Simon M
Published in Journal of medicinal chemistry (24.09.2020)

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β‑Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease

β‑Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease

by Hilpert, Hans, Guba, Wolfgang, Woltering, Thomas J, Wostl, Wolfgang, Pinard, Emmanuel, Mauser, Harald, Mayweg, Alexander V, Rogers-Evans, Mark, Humm, Roland, Krummenacher, Daniela, Muser, Thorsten, Schnider, Christian, Jacobsen, Helmut, Ozmen, Laurence, Bergadano, Alessandra, Banner, David W, Hochstrasser, Remo, Kuglstatter, Andreas, David-Pierson, Pascale, Fischer, Holger, Polara, Alessandra, Narquizian, Robert
Published in Journal of medicinal chemistry (23.05.2013)

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BACE1 inhibitors: A head group scan on a series of amides

BACE1 inhibitors: A head group scan on a series of amides

by Woltering, Thomas J., Wostl, Wolfgang, Hilpert, Hans, Rogers-Evans, Mark, Pinard, Emmanuel, Mayweg, Alexander, Göbel, Martin, Banner, David W., Benz, Jörg, Travagli, Massimiliano, Pollastrini, Martina, Marconi, Guido, Gabellieri, Emanuele, Guba, Wolfgang, Mauser, Harald, Andreini, Matteo, Jacobsen, Helmut, Power, Eoin, Narquizian, Robert
Published in Bioorganic & medicinal chemistry letters (15.07.2013)

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An Intramolecular [2 + 2] Photocycloaddition Approach to Conformationally Restricted Bis-Pyrrolidines

An Intramolecular [2 + 2] Photocycloaddition Approach to Conformationally Restricted Bis-Pyrrolidines

by Fort, Diego A, Woltering, Thomas J, Alker, André M, Bach, Thorsten
Published in Journal of organic chemistry (01.08.2014)

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Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

by Fort, Diego A., Woltering, Thomas J., Nettekoven, Matthias, Knust, Henner, Bach, Thorsten
Published in Angewandte Chemie (International ed.) (01.10.2012)

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Conformationally restricted pyrrolidines by intramolecular [2+2] photocycloaddition reactions

Conformationally restricted pyrrolidines by intramolecular [2+2] photocycloaddition reactions

by Fort, Diego A., Woltering, Thomas J., Nettekoven, Matthias, Knust, Henner, Bach, Thorsten
Published in Chemical communications (Cambridge, England) (14.04.2013)

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Synthesis and characterization of 1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 4. In vivo active potent and selective non-competitive metabotropic glutamate receptor 2/3 antagonists

Synthesis and characterization of 1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 4. In vivo active potent and selective non-competitive metabotropic glutamate receptor 2/3 antagonists

by Woltering, Thomas J., Wichmann, Jürgen, Goetschi, Erwin, Knoflach, Frédéric, Ballard, Theresa M., Huwyler, Jörg, Gatti, Silvia
Published in Bioorganic & medicinal chemistry letters (01.12.2010)

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PHOTOCHEMICAL REACTIONS OF PROP-2-ENYL AND PROP-2-YNYL SUBSTITUTED 4-AMINOMETHYL- AND 4-OXYMETHYL-2(5H)-FURANONES

PHOTOCHEMICAL REACTIONS OF PROP-2-ENYL AND PROP-2-YNYL SUBSTITUTED 4-AMINOMETHYL- AND 4-OXYMETHYL-2(5H)-FURANONES

by Fort, Diego A., Woltering, Thomas J., Alker, Andre M., Bach, Thorsten
Published in Heterocycles (01.01.2014)

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Enantioselective functionalisation of the C-2' position of 1,2,3,4,5-pentamethylazaferrocene via sparteine mediated lithiation: potential new ligands for asymmetric catalysis

Enantioselective functionalisation of the C-2' position of 1,2,3,4,5-pentamethylazaferrocene via sparteine mediated lithiation: potential new ligands for asymmetric catalysis

by Anderson, James C., Osborne, James D., Woltering, Thomas J.
Published in Organic & biomolecular chemistry (21.01.2008)

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Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: New potent non-competitive metabotropic glutamate receptor 2/3 antagonists. Part 1

Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: New potent non-competitive metabotropic glutamate receptor 2/3 antagonists. Part 1

by Woltering, Thomas J., Adam, Geo, Alanine, Alexander, Wichmann, Jürgen, Knoflach, Frédéric, Mutel, Vincent, Gatti, Silvia
Published in Bioorganic & medicinal chemistry letters (15.12.2007)

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Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 2. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists

Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 2. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists

by Woltering, Thomas J., Adam, Geo, Wichmann, Jürgen, Goetschi, Erwin, Kew, James N.C., Knoflach, Frédéric, Mutel, Vincent, Gatti, Silvia
Published in Bioorganic & medicinal chemistry (01.02.2008)

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Synthesis and characterization of 1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 3. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists

Synthesis and characterization of 1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 3. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists

by Woltering, Thomas J., Wichmann, Jürgen, Goetschi, Erwin, Adam, Geo, Kew, James N.C., Knoflach, Frédéric, Ballard, Theresa M., Huwyler, Jörg, Mutel, Vincent, Gatti, Silvia
Published in Bioorganic & medicinal chemistry (15.04.2008)

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Enantioselective functionalisation of the C-2′ position of 1,2,3,4,5-pentamethylazaferroceneviasparteine mediated lithiation: potential new ligands for asymmetric catalysis

Enantioselective functionalisation of the C-2′ position of 1,2,3,4,5-pentamethylazaferroceneviasparteine mediated lithiation: potential new ligands for asymmetric catalysis

by Anderson, James C., Osborne, James D., Woltering, Thomas J.
Published in Organic & biomolecular chemistry (2008)

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Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

by Fort, Diego A., Woltering, Thomas J., Nettekoven, Matthias, Knust, Henner, Bach, Thorsten
Published in Angewandte Chemie (01.10.2012)

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A Real-World Perspective on Molecular Design

A Real-World Perspective on Molecular Design

by Kuhn, Bernd, Guba, Wolfgang, Hert, Jérôme, Banner, David, Bissantz, Caterina, Ceccarelli, Simona, Haap, Wolfgang, Körner, Matthias, Kuglstatter, Andreas, Lerner, Christian, Mattei, Patrizio, Neidhart, Werner, Pinard, Emmanuel, Rudolph, Markus G, Schulz-Gasch, Tanja, Woltering, Thomas, Stahl, Martin
Published in Journal of medicinal chemistry (12.05.2016)

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Design, synthesis and biological evaluation of aryl-substituted sialyl Lewis X mimetics prepared via cross-metathesis of C-fucopeptides

Design, synthesis and biological evaluation of aryl-substituted sialyl Lewis X mimetics prepared via cross-metathesis of C-fucopeptides

by Huwe, Christoph M, Woltering, Thomas J, Jiricek, Jan, Weitz-Schmidt, Gabriele, Wong, Chi-Huey
Published in Bioorganic & medicinal chemistry (01.05.1999)

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Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

by Fort, Diego A., Woltering, Thomas J., Nettekoven, Matthias, Knust, Henner, Bach, Thorsten
Published in Angewandte Chemie (01.10.2012)

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Characterization of (2S,2′R,3′R)‐2‐(2′,3′‐[3H]‐Dicarboxycyclopropyl)glycine Binding in Rat Brain

Characterization of (2S,2′R,3′R)‐2‐(2′,3′‐[3H]‐Dicarboxycyclopropyl)glycine Binding in Rat Brain

by Mutel, Vincent, Adam, Geo, Chaboz, Sylvie, Kemp, John A., Klingelschmidt, Agnés, Messer, Jürg, Wichmann, Jürgen, Woltering, Thomas, Richards, John Grayson
Published in Journal of neurochemistry (01.12.1998)

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ChemInform Abstract: An Intramolecular [2 + 2] Photocycloaddition Approach to Conformationally Restricted Bis-pyrrolidines

ChemInform Abstract: An Intramolecular [2 + 2] Photocycloaddition Approach to Conformationally Restricted Bis-pyrrolidines

by Fort, Diego A., Woltering, Thomas J., Alker, Andre M., Bach, Thorsten
Published in ChemInform (01.02.2015)

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ChemInform Abstract: Photochemical Reactions of Prop-2-enyl and Prop-2-ynyl Substituted 4-Aminomethyl- and 4-Oxymethyl-2(5H)-furanones

ChemInform Abstract: Photochemical Reactions of Prop-2-enyl and Prop-2-ynyl Substituted 4-Aminomethyl- and 4-Oxymethyl-2(5H)-furanones

by Bach, Thorsten, Fort, Diego, J. Woltering, Thomas A., Alker, Andre M.
Published in ChemInform (10.06.2014)

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