5′-(E)-Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA-GalNAc Conjugates
Parmar, Rubina, Willoughby, Jennifer L. S., Liu, Jingxuan, Foster, Donald J., Brigham, Benjamin, Theile, Christopher S., Charisse, Klaus, Akinc, Akin, Guidry, Erin, Pei, Yi, Strapps, Walter, Cancilla, Mark, Stanton, Matthew G., Rajeev, Kallanthottathil G., Sepp-Lorenzino, Laura, Manoharan, Muthiah, Meyers, Rachel, Maier, Martin A., Jadhav, Vasant
Published in Chembiochem : a European journal of chemical biology (02.06.2016)
Published in Chembiochem : a European journal of chemical biology (02.06.2016)
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Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)
Methot, Joey L., Chakravarty, Prasun K., Chenard, Melissa, Close, Joshua, Cruz, Jonathan C., Dahlberg, William K., Fleming, Judith, Hamblett, Christopher L., Hamill, Julie E., Harrington, Paul, Harsch, Andreas, Heidebrecht, Richard, Hughes, Bethany, Jung, Joon, Kenific, Candia M., Kral, Astrid M., Meinke, Peter T., Middleton, Richard E., Ozerova, Nicole, Sloman, David L., Stanton, Matthew G., Szewczak, Alexander A., Tyagarajan, Sriram, Witter, David J., Paul Secrist, J., Miller, Thomas A.
Published in Bioorganic & medicinal chemistry (01.02.2008)
Published in Bioorganic & medicinal chemistry (01.02.2008)
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Systematic chemical modifications of single stranded siRNAs significantly improved CTNNB1 mRNA silencing
Chang, Wonsuk, Pei, Yi, Guidry, Erin N., Zewge, Daniel, Parish, Craig A., Sherer, Edward C., DiMuzio, Jillian, Zhang, Hangchun, South, Victoria J., Strapps, Walter R., Sepp-Lorenzino, Laura, Colletti, Steven L., Stanton, Matthew G.
Published in Bioorganic & medicinal chemistry letters (15.09.2016)
Published in Bioorganic & medicinal chemistry letters (15.09.2016)
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The development of an in vitro assay to screen lipid based nanoparticles for siRNA delivery
Zhang, Ye, Arrington, Leticia, Boardman, David, Davis, Jared, Xu, Yan, DiFelice, Katie, Stirdivant, Steve, Wang, Weimin, Budzik, Brian, Bawiec, Jack, Deng, James, Beutner, Greg, Seifried, Darla, Stanton, Matthew, Gindy, Marian, Leone, Anthony
Published in Journal of controlled release (28.01.2014)
Published in Journal of controlled release (28.01.2014)
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Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties
Sloman, David L., Noucti, Njamkou, Altman, Michael D., Chen, Dapeng, Mislak, Andrea C., Szewczak, Alexander, Hayashi, Mansuo, Warren, Lee, Dellovade, Tammy, Wu, Zhenhua, Marcus, Jacob, Walker, Deborah, Su, Hua-Poo, Edavettal, Suzanne C., Munshi, Sanjeev, Hutton, Michael, Nuthall, Hugh, Stanton, Matthew G.
Published in Bioorganic & medicinal chemistry letters (01.09.2016)
Published in Bioorganic & medicinal chemistry letters (01.09.2016)
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Inside Cover: 5′-(E)-Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA-GalNAc Conjugates (ChemBioChem 11/2016)
Parmar, Rubina, Willoughby, Jennifer L. S., Liu, Jingxuan, Foster, Donald J., Brigham, Benjamin, Theile, Christopher S., Charisse, Klaus, Akinc, Akin, Guidry, Erin, Pei, Yi, Strapps, Walter, Cancilla, Mark, Stanton, Matthew G., Rajeev, Kallanthottathil G., Sepp-Lorenzino, Laura, Manoharan, Muthiah, Meyers, Rachel, Maier, Martin A., Jadhav, Vasant
Published in Chembiochem : a European journal of chemical biology (02.06.2016)
Published in Chembiochem : a European journal of chemical biology (02.06.2016)
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Discovery of Isonicotinamide Derived β-Secretase Inhibitors: In Vivo Reduction of β-Amyloid
Stanton, Matthew G, Stauffer, Shaun R, Gregro, Alison R, Steinbeiser, Melissa, Nantermet, Philippe, Sankaranarayanan, Sethu, Price, Eric A, Wu, Guoxin, Crouthamel, Ming-Chih, Ellis, Joan, Lai, Ming-Tain, Espeseth, Amy S, Shi, Xiao-Ping, Jin, Lixia, Colussi, Dennis, Pietrak, Beth, Huang, Qian, Xu, Min, Simon, Adam J, Graham, Samuel L, Vacca, Joseph P, Selnick, Harold
Published in Journal of medicinal chemistry (26.07.2007)
Published in Journal of medicinal chemistry (26.07.2007)
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Quantitative Analysis of Histone Deacetylase-1 Selective Histone Modifications by Differential Mass Spectrometry
Lee, Anita Y. H, Paweletz, Cloud P, Pollock, Roy M, Settlage, Robert E, Cruz, Jonathan C, Secrist, J. Paul, Miller, Thomas A, Stanton, Matthew G, Kral, Astrid M, Ozerova, Nicole D. S, Meng, Fanyu, Yates, Nathan A, Richon, Victoria, Hendrickson, Ronald C
Published in Journal of proteome research (01.12.2008)
Published in Journal of proteome research (01.12.2008)
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Fluorinated piperidine acetic acids as γ-secretase modulators
Stanton, Matthew G., Hubbs, Jed, Sloman, David, Hamblett, Christopher, Andrade, Paula, Angagaw, Minilik, Bi, Grace, Black, Regina M., Crispino, Jamie, Cruz, Jonathan C., Fan, Eric, Farris, Georgia, Hughes, Bethany L., Kenific, Candia M., Middleton, Richard E., Nikov, George, Sajonz, Peter, Shah, Sanjiv, Shomer, Nirah, Szewczak, Alexander A., Tanga, Flobert, Tudge, Matthew T., Shearman, Mark, Munoz, Benito
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
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The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors
Hamblett, Christopher L., Methot, Joey L., Mampreian, Dawn M., Sloman, David L., Stanton, Matthew G., Kral, Astrid M., Fleming, Judith C., Cruz, Jonathan C., Chenard, Melissa, Ozerova, Nicole, Hitz, Anna M., Wang, Hongmei, Deshmukh, Sujal V., Nazef, Naim, Harsch, Andreas, Hughes, Bethany, Dahlberg, William K., Szewczak, Alex A., Middleton, Richard E., Mosley, Ralph T., Secrist, J. Paul, Miller, Thomas A.
Published in Bioorganic & medicinal chemistry letters (01.10.2007)
Published in Bioorganic & medicinal chemistry letters (01.10.2007)
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Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind β-secretase in a N-terminal 10s-loop down conformation
Stauffer, Shaun R., Stanton, Matthew G., Gregro, Alison R., Steinbeiser, Melissa A., Shaffer, Jennifer R., Nantermet, Philippe G., Barrow, James C., Rittle, Kenneth E., Collusi, Dennis, Espeseth, Amy S., Lai, Ming-Tain, Pietrak, Beth L., Holloway, M. Katharine, McGaughey, Georgia B., Munshi, Sanjeev K., Hochman, Jerome H., Simon, Adam J., Selnick, Harold G., Graham, Samuel L., Vacca, Joseph P.
Published in Bioorganic & medicinal chemistry letters (15.03.2007)
Published in Bioorganic & medicinal chemistry letters (15.03.2007)
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“New” Catalysts for the Ester-Interchange Reaction: The Role of Alkali-Metal Alkoxide Clusters in Achieving Unprecedented Reaction Rates
Stanton, Matthew G, Allen, Cara B, Kissling, Rebecca M, Lincoln, Alice L, Gagné, Michel R
Published in Journal of the American Chemical Society (24.06.1998)
Published in Journal of the American Chemical Society (24.06.1998)
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Azaindoles: moderately basic P1 groups for enhancing the selectivity of thrombin inhibitors
Sanderson, Philip E.J., Stanton, Matthew G., Dorsey, Bruce D., Lyle, Terry A., McDonough, Colleen, Sanders, William M., Savage, Kelly L., Naylor-Olsen, Adel M., Krueger, Julie A., Lewis, S.Dale, Lucas, Bobby J., Lynch, Joseph J., Yan, Youwei
Published in Bioorganic & medicinal chemistry letters (10.03.2003)
Published in Bioorganic & medicinal chemistry letters (10.03.2003)
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