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A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation

A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation

by Naret, Timothée, Bignon, Jérôme, Bernadat, Guillaume, Benchekroun, Mohamed, Levaique, Helene, Lenoir, Christine, Dubois, Joelle, Pruvost, Alain, Saller, François, Borgel, Delphine, Manoury, Boris, Leblais, Veronique, Darrigrand, Romain, Apcher, Sébastien, Brion, Jean-Daniel, Schmitt, Etienne, Leroux, Frédéric R., Alami, Mouad, Hamze, Abdallah
Published in European journal of medicinal chemistry (01.01.2018)

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Synthesis and structural properties of hexaaza[5]helicene containing two [1,2,3]triazolo[1,5-a]pyridine moieties

Synthesis and structural properties of hexaaza[5]helicene containing two [1,2,3]triazolo[1,5-a]pyridine moieties

by Adam, Rosa, Ballesteros-Garrido, Rafael, Vallcorba, Oriol, Abarca, Belén, Ballesteros, Rafael, Leroux, Frédéric R., Colobert, Françoise, Amigó, José M., Rius, Jordi
Published in Tetrahedron letters (07.08.2013)

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Three-Dimensional Characterization of Helical Silver Nanochains Mediated by Protein Assemblies

Three-Dimensional Characterization of Helical Silver Nanochains Mediated by Protein Assemblies

by Leroux, Frederic, Gysemans, Maarten, Bals, Sara, Batenburg, Kees Joost, Snauwaert, Johan, Verbiest, Thierry, Van Haesendonck, Chris, Van Tendeloo, Gustaaf
Published in Advanced materials (Weinheim) (18.05.2010)

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Ketenimines as Intermediates To Access Difluoromethoxylated Scaffolds

Ketenimines as Intermediates To Access Difluoromethoxylated Scaffolds

by Loison, Anaïs, Hanquet, Gilles, Toulgoat, Fabien, Billard, Thierry, Panossian, Armen, Leroux, Frédéric R.
Published in Organic letters (18.11.2022)

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Synthesis of diversely fluorinated pyrazoles as novel active agrochemical ingredients

Synthesis of diversely fluorinated pyrazoles as novel active agrochemical ingredients

by Giornal, Florence, Pazenok, Sergiy, Rodefeld, Lars, Lui, Norbert, Vors, Jean-Pierre, Leroux, Frédéric R.
Published in Journal of fluorine chemistry (01.08.2013)

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Deprotonative Functionalization of the Difluoromethyl Group

Deprotonative Functionalization of the Difluoromethyl Group

by Santos, Laura, Panossian, Armen, Donnard, Morgan, Vors, Jean-Pierre, Pazenok, Sergii, Bernier, David, Leroux, Frédéric R
Published in Organic letters (06.11.2020)

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Direct Deprotonative Functionalization of α,α‐Difluoromethyl Ketones using a Catalytic Organosuperbase

Direct Deprotonative Functionalization of α,α‐Difluoromethyl Ketones using a Catalytic Organosuperbase

by Messara, Amélia, Panossian, Armen, Mikami, Koichi, Hanquet, Gilles, Leroux, Frédéric R.
Published in Angewandte Chemie International Edition (01.03.2023)

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Comprehensive Study and Development of a Metal‐Free and Mild Nucleophilic Trifluoromethoxylation

Comprehensive Study and Development of a Metal‐Free and Mild Nucleophilic Trifluoromethoxylation

by Bonnefoy, Clémence, Panossian, Armen, Hanquet, Gilles, Leroux, Frédéric R., Toulgoat, Fabien, Billard, Thierry
Published in Chemistry : a European journal (15.08.2023)

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Versatile Access to Tetrasubstituted 2‑Amidoacroleins through Formal Silylformylation of Ynamides

Versatile Access to Tetrasubstituted 2‑Amidoacroleins through Formal Silylformylation of Ynamides

by Golling, Stéphane, Leroux, Frédéric R, Donnard, Morgan
Published in Organic letters (15.10.2021)

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Palladium‐Catalyzed Silylcyanation of Ynamides: Regio‐ and Stereoselective Access to Tetrasubstituted 3‐Silyl‐2‐Aminoacrylonitriles

Palladium‐Catalyzed Silylcyanation of Ynamides: Regio‐ and Stereoselective Access to Tetrasubstituted 3‐Silyl‐2‐Aminoacrylonitriles

by Hansjacob, Pierre, Leroux, Frédéric R., Gandon, Vincent, Donnard, Morgan
Published in Angewandte Chemie International Edition (28.03.2022)

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Asymmetric α‑Sulfonyl- and α‑Phosphoryl-Oxylation of Ketones by a Chiral Hypervalent Iodine(III)

Asymmetric α‑Sulfonyl- and α‑Phosphoryl-Oxylation of Ketones by a Chiral Hypervalent Iodine(III)

by Levitre, Guillaume, Dumoulin, Audrey, Retailleau, Pascal, Panossian, Armen, Leroux, Frédéric R, Masson, Géraldine
Published in Journal of organic chemistry (17.11.2017)

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Direct Access to 2,3-Disubstituted Amido-Indenones through Annulation of 2‑Iodobenzaldehydes with Ynamides

Direct Access to 2,3-Disubstituted Amido-Indenones through Annulation of 2‑Iodobenzaldehydes with Ynamides

by Golling, Stéphane, Hansjacob, Pierre, Bami, Nassim, Leroux, Frédéric R., Donnard, Morgan
Published in Journal of organic chemistry (16.12.2022)

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Zinc‐Catalyzed Hydrocyanation of Ynamides and Photoisomerization, a General and Selective Access to E and Z Trisubstituted α‐Enamidonitriles

Zinc‐Catalyzed Hydrocyanation of Ynamides and Photoisomerization, a General and Selective Access to E and Z Trisubstituted α‐Enamidonitriles

by Hansjacob, Pierre, Leroux, Frédéric R., Donnard, Morgan
Published in Chemistry : a European journal (26.05.2023)

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Recent advances in transition metal-catalyzed Csp(2)-monofluoro-, difluoro-, perfluoromethylation and trifluoromethylthiolation

Recent advances in transition metal-catalyzed Csp(2)-monofluoro-, difluoro-, perfluoromethylation and trifluoromethylthiolation

by Landelle, Grégory, Panossian, Armen, Pazenok, Sergiy, Vors, Jean-Pierre, Leroux, Frédéric R
Published in Beilstein journal of organic chemistry (15.11.2013)

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A Major Advance in the Synthesis of Fluoroalkyl Pyrazoles: Tuneable Regioselectivity and Broad Substitution Patterns

A Major Advance in the Synthesis of Fluoroalkyl Pyrazoles: Tuneable Regioselectivity and Broad Substitution Patterns

by Schmitt, Etienne, Panossian, Armen, Vors, Jean-Pierre, Funke, Christian, Lui, Norbert, Pazenok, Sergiy, Leroux, Frédéric R.
Published in Chemistry : a European journal (01.08.2016)

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Synthesis and Use of Trifluoromethylthiolated Ketenimines

Synthesis and Use of Trifluoromethylthiolated Ketenimines

by Guérin, Thomas, Pikun, Nadiia V., Morioka, Ryutaro, Panossian, Armen, Hanquet, Gilles, Leroux, Frédéric R.
Published in Chemistry : a European journal (20.11.2020)

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Atropodiastereoselective CH Olefination of Biphenyl p-Tolyl Sulfoxides with Acrylates

Atropodiastereoselective CH Olefination of Biphenyl p-Tolyl Sulfoxides with Acrylates

by Wesch, Thomas, Leroux, Frédéric R., Colobert, Françoise
Published in Advanced synthesis & catalysis (12.08.2013)

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Unlocking the Power of Acyl Fluorides: A Comprehensive Guide to Synthesis and Properties

Unlocking the Power of Acyl Fluorides: A Comprehensive Guide to Synthesis and Properties

by Bonnefoy, Clemence, Gallego, Adrien, Delobel, Clement, Raynal, Betty, Decourt, Maxime, Chefdeville, Emmanuel, Hanquet, Gilles, Panossian, Armen, Leroux, Frederic R., Toulgoat, Fabien, Billard, Thierry
Published in European journal of organic chemistry (13.05.2024)

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Ruthenium‐Catalyzed Synthesis of Aryl and Alkenyl Halides from Fluorosulfonates

Ruthenium‐Catalyzed Synthesis of Aryl and Alkenyl Halides from Fluorosulfonates

by Plaçais, Clotilde, Kaldas, Sherif J., Donnard, Morgan, Panossian, Armen, Bernier, David, Pazenok, Sergii, Leroux, Frédéric R.
Published in Chemistry : a European journal (20.07.2023)

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Recent synthetic methods towards the –OCHF2 moiety

Recent synthetic methods towards the –OCHF2 moiety

by Loison, Anaïs, Toulgoat, Fabien, Billard, Thierry, Hanquet, Gilles, Panossian, Armen, Leroux, Frédéric R.
Published in Tetrahedron (22.10.2021)

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