Efficient Co-crystal Screening Using Solution-Mediated Phase Transformation
Zhang, Geoff G.Z., Henry, Rodger F., Borchardt, Thomas B., Lou, Xiaochun
Published in Journal of pharmaceutical sciences (01.05.2007)
Published in Journal of pharmaceutical sciences (01.05.2007)
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Journal Article
Thermochemistry and Conformational Polymorphism of a Hexamorphic Crystal System
Yu, Lian, Stephenson, Gregory A, Mitchell, Christine A, Bunnell, Charles A, Snorek, Sharon V, Bowyer, J. Joe, Borchardt, Thomas B, Stowell, Joseph G, Byrn, Stephen R
Published in Journal of the American Chemical Society (02.02.2000)
Published in Journal of the American Chemical Society (02.02.2000)
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Mechanistic Physiologically Based Pharmacokinetic Modeling of the Dissolution and Food Effect of a Biopharmaceutics Classification System IV Compound—The Venetoclax Story
Emami Riedmaier, Arian, Lindley, David J., Hall, Jeffrey A., Castleberry, Steven, Slade, Russell T., Stuart, Patricia, Carr, Robert A., Borchardt, Thomas B., Bow, Daniel A.J., Nijsen, Marjoleen
Published in Journal of pharmaceutical sciences (01.01.2018)
Published in Journal of pharmaceutical sciences (01.01.2018)
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Novel Physics-Based Ensemble Modeling Approach That Utilizes 3D Molecular Conformation and Packing to Access Aqueous Thermodynamic Solubility: A Case Study of Orally Available Bromodomain and Extraterminal Domain Inhibitor Lead Optimization Series
Hong, Richard S, Mattei, Alessandra, Sheikh, Ahmad Y, Bhardwaj, Rajni Miglani, Bellucci, Michael A, McDaniel, Keith F, Pierce, M. Olivia, Sun, Guangxu, Li, Sizhu, Wang, Lingle, Mondal, Sayan, Ji, Jianguo, Borchardt, Thomas B
Published in Journal of chemical information and modeling (22.03.2021)
Published in Journal of chemical information and modeling (22.03.2021)
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A "hidden" co-crystal of caffeine and adipic acid
Bucar, Dejan-Kresimir, Henry, Rodger F, Lou, Xiaochun, Borchardt, Thomas B, Zhang, Geoff G Z
Published in Chemical communications (Cambridge, England) (01.01.2007)
Published in Chemical communications (Cambridge, England) (01.01.2007)
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Development of a Scalable Synthesis of Dipeptidyl Peptidase-4 Inhibitor ABT-279
McDermott, Todd S, Bhagavatula, Lakshmi, Borchardt, Thomas B, Engstrom, Kenneth M, Gandarilla, Jorge, Kotecki, Brian J, Kruger, Albert W, Rozema, Michael J, Sheikh, Ahmad Y, Wagaw, Seble H, Wittenberger, Steven J
Published in Organic process research & development (20.11.2009)
Published in Organic process research & development (20.11.2009)
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Chromoisomers and Polymorphs of 9-Phenylacridinium Hydrogen Sulfate
Toma, Pascal H, Kelley, Michael P, Borchardt, Thomas B, Byrn, Stephen R, Kahr, Bart
Published in Chemistry of materials (01.08.1994)
Published in Chemistry of materials (01.08.1994)
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Conformational Color Polymorphism and Control of Crystallization of 5‐Methyl‐2‐[(4‐methyl‐2‐nitrophenyl)amino]‐3‐thiophenecarbonitrile
He, Xiaorong, Griesser, Ulrich J., Stowell, Joseph G., Borchardt, Thomas B., Byrn, Stephen R.
Published in Journal of pharmaceutical sciences (01.03.2001)
Published in Journal of pharmaceutical sciences (01.03.2001)
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Journal Article
(3S,4R)-3-에틸-4-(3H-이미다조[1,2-a]피롤로[2,3-e]-피라진-8-일)-N-피롤리딘-1-카복스아미드 및 이의 고체상 형태의 제조 방법
ALLIAN AYMAN D, OTHMAN AHMED A, BHAGAVATULA LAKSHMI, MULHERN MATHEW M, MARROUM PATRICK J, BORCHARDT THOMAS B, NORDSTROEM LARS F, SHEIKH AHMAD Y, MOHAMED MOHAMED ESLAM F, ROZEMA MICHAEL J, MAYER PETER T, JAYANTH JAYANTHY
Year of Publication 16.07.2018
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Year of Publication 16.07.2018
Patent
ABT-263 CRYSTALLINE FORMS AND SOLVATES FOR USE IN TREATING BCL-2 PROTEIN RELATED DISEASES
BORCHARDT THOMAS B, ZHANG GEOFF G.Z, BRACKEMEYER PAUL J, CATRON NATHANIEL D
Year of Publication 01.08.2012
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Year of Publication 01.08.2012
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CRYSTALLINE INDAZOLE-DERIVED CHEMOTHERAPEUTIC
BORCHARDT THOMAS B, CHU KUNG ALEXANDER, BORDAWEKAR SHAILENDRA V, ROZEMA MICHAEL J
Year of Publication 28.07.2010
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Year of Publication 28.07.2010
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Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
Allian, Ayman, Nordstrom, Fredrik Lars, Sheikh, Ahmad Y, Borchardt, Thomas B
Year of Publication 20.06.2023
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Year of Publication 20.06.2023
Patent
Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
Allian, Ayman, Nordstrom, Fredrik Lars, Sheikh, Ahmad Y, Borchardt, Thomas B
Year of Publication 30.05.2023
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Year of Publication 30.05.2023
Patent