Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion
Gutierrez, Jahir M., Feizi, Amir, Li, Shangzhong, Kallehauge, Thomas B., Hefzi, Hooman, Grav, Lise M., Ley, Daniel, Baycin Hizal, Deniz, Betenbaugh, Michael J., Voldborg, Bjorn, Faustrup Kildegaard, Helene, Min Lee, Gyun, Palsson, Bernhard O., Nielsen, Jens, Lewis, Nathan E.
Published in Nature communications (02.01.2020)
Published in Nature communications (02.01.2020)
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Accelerated homology-directed targeted integration of transgenes in Chinese hamster ovary cells via CRISPR/Cas9 and fluorescent enrichment
Lee, Jae Seong, Grav, Lise Marie, Pedersen, Lasse Ebdrup, Lee, Gyun Min, Kildegaard, Helene Faustrup
Published in Biotechnology and bioengineering (01.11.2016)
Published in Biotechnology and bioengineering (01.11.2016)
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Multiplex secretome engineering enhances recombinant protein production and purity
Kol, Stefan, Ley, Daniel, Wulff, Tune, Decker, Marianne, Arnsdorf, Johnny, Schoffelen, Sanne, Hansen, Anders Holmgaard, Jensen, Tanja Lyholm, Gutierrez, Jahir M., Chiang, Austin W. T., Masson, Helen O., Palsson, Bernhard O., Voldborg, Bjørn G., Pedersen, Lasse Ebdrup, Kildegaard, Helene Faustrup, Lee, Gyun Min, Lewis, Nathan E.
Published in Nature communications (20.04.2020)
Published in Nature communications (20.04.2020)
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Understanding of decreased sialylation of Fc‐fusion protein in hyperosmotic recombinant Chinese hamster ovary cell culture: N‐glycosylation gene expression and N‐linked glycan antennary profile
Lee, Jong Hyun, Jeong, Yeong Ran, Kim, Yeon‐Gu, Lee, Gyun Min
Published in Biotechnology and bioengineering (01.08.2017)
Published in Biotechnology and bioengineering (01.08.2017)
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Amplification of EBNA-1 through a single-plasmid vector-based gene amplification system in HEK293 cells as an efficient transient gene expression system
Park, Sun-Hye, Park, Jong-Ho, Lee, Joo-Hyoung, Lee, Hoon-Min, Kang, Yeon-Ju, Lee, Eun-Ji, Shin, Seunghyeon, Lee, Gyun Min, Kim, Yeon-Gu
Published in Applied microbiology and biotechnology (2021)
Published in Applied microbiology and biotechnology (2021)
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Effect of glucose feeding on the glycosylation quality of antibody produced by a human cell line, F2N78, in fed-batch culture
Seo, Jin Seok, Min, Byung Sup, Kim, Yeon Jung, Cho, Jong Moon, Baek, Eric, Cho, Myung Sam, Lee, Gyun Min
Published in Applied microbiology and biotechnology (01.04.2014)
Published in Applied microbiology and biotechnology (01.04.2014)
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CHO cells in biotechnology for production of recombinant proteins: current state and further potential
Kim, Jee Yon, Kim, Yeon-Gu, Lee, Gyun Min
Published in Applied microbiology and biotechnology (01.02.2012)
Published in Applied microbiology and biotechnology (01.02.2012)
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Untangling the mechanism of 3‐methyladenine in enhancing the specific productivity: Transcriptome analysis of recombinant Chinese hamster ovary cells treated with 3‐methyladenine
Baek, Eric, Lee, Jae Seong, Lee, Gyun Min
Published in Biotechnology and bioengineering (01.09.2018)
Published in Biotechnology and bioengineering (01.09.2018)
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Anti-Apoptosis Engineering for Improved Protein Production from CHO Cells
Baek, Eric, Noh, Soo Min, Lee, Gyun Min
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2017)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2017)
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Selection strategies for the establishment of recombinant Chinese hamster ovary cell line with dihydrofolate reductase-mediated gene amplification
Jun, Seung Chul, Kim, Min Soo, Baik, Jong Youn, Hwang, Sun Ok, Lee, Gyun Min
Published in Applied microbiology and biotechnology (01.11.2005)
Published in Applied microbiology and biotechnology (01.11.2005)
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Understanding of altered N-glycosylation-related gene expression in recombinant Chinese hamster ovary cells subjected to elevated ammonium concentration by digital mRNA counting
Ha, Tae Kwang, Kim, Yeon-Gu, Lee, Gyun Min
Published in Biotechnology and bioengineering (01.08.2015)
Published in Biotechnology and bioengineering (01.08.2015)
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