Use of miRNA Response Sequences to Block Off-target Replication and Increase the Safety of an Unattenuated, Glioblastoma-targeted Oncolytic HSV
Mazzacurati, Lucia, Marzulli, Marco, Reinhart, Bonnie, Miyagawa, Yoshitaka, Uchida, Hiroaki, Goins, William F, Li, Aofei, Kaur, Balveen, Caligiuri, Michael, Cripe, Timothy, Chiocca, Nino, Amankulor, Nduka, Cohen, Justus B, Glorioso, Joseph C, Grandi, Paola
Published in Molecular therapy (01.01.2015)
Published in Molecular therapy (01.01.2015)
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Varicella-zoster virus early infection but not complete replication is required for the induction of chronic hypersensitivity in rat models of postherpetic neuralgia
Warner, Benjamin E, Yee, Michael B, Zhang, Mingdi, Hornung, Rebecca S, Kaufer, Benedikt B, Visalli, Robert J, Kramer, Phillip R, Goins, William F, Kinchington, Paul R
Published in PLoS pathogens (01.07.2021)
Published in PLoS pathogens (01.07.2021)
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Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFRα1 for Specific Infection of Breast Cancer Cells
Hall, Bonnie L, Leronni, Daniela, Miyagawa, Yoshitaka, Goins, William F, Glorioso, Joseph C, Cohen, Justus B
Published in International journal of molecular sciences (21.11.2020)
Published in International journal of molecular sciences (21.11.2020)
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Journal Article
Effective Treatment of an Orthotopic Xenograft Model of Human Glioblastoma Using an EGFR-retargeted Oncolytic Herpes Simplex Virus
Uchida, Hiroaki, Marzulli, Marco, Nakano, Kenji, Goins, William F, Chan, Janet, Hong, Chang-Sook, Mazzacurati, Lucia, Yoo, Ji Young, Haseley, Amy, Nakashima, Hiroshi, Baek, Hyunjung, Kwon, Heechung, Kumagai, Izumi, Kuroki, Masahide, Kaur, Balveen, Chiocca, E Antonio, Grandi, Paola, Cohen, Justus B, Glorioso, Joseph C
Published in Molecular therapy (01.03.2013)
Published in Molecular therapy (01.03.2013)
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Journal Article
Novel mutations in UL24 and gH rescue efficient infection of an HSV vector retargeted to TrkA
Marzulli, Marco, Hall, Bonnie L., Zhang, Mingdi, Goins, William F., Cohen, Justus B., Glorioso, Joseph C.
Published in Molecular therapy. Methods & clinical development (14.09.2023)
Published in Molecular therapy. Methods & clinical development (14.09.2023)
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Journal Article
Evaluation of parameters for efficient purification and long-term storage of herpes simplex virus-based vectors
Kuroda, Seiji, Miyagawa, Yoshitaka, Sukegawa, Makoto, Tomono, Taro, Yamamoto, Motoko, Adachi, Kumi, Verlengia, Gianluca, Goins, William F., Cohen, Justus B., Glorioso, Joseph C., Okada, Takashi
Published in Molecular therapy. Methods & clinical development (08.09.2022)
Published in Molecular therapy. Methods & clinical development (08.09.2022)
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A Double Mutation in Glycoprotein gB Compensates for Ineffective gD-Dependent Initiation of Herpes Simplex Virus Type 1 Infection
UCHIDA, Hiroaki, CHAN, Janet, GOINS, William F, GRANDI, Paola, KUMAGAI, Izumi, COHEN, Justus B, GLORIOSO, Joseph C
Published in Journal of Virology (01.12.2010)
Published in Journal of Virology (01.12.2010)
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Protocol Optimization for the Production of the Non-Cytotoxic JΔNI5 HSV Vector Deficient in Expression of Immediately Early Genes
Kuroda, Seiji, Miyagawa, Yoshitaka, Sato, Yuriko, Yamamoto, Motoko, Adachi, Kumi, Kinoh, Hiromi, Goins, William F., Cohen, Justus B., Glorioso, Joseph C., Taniai, Nobuhiko, Yoshida, Hiroshi, Okada, Takashi
Published in Molecular therapy. Methods & clinical development (12.06.2020)
Published in Molecular therapy. Methods & clinical development (12.06.2020)
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Journal Article
Equine Herpesvirus 1 Enters Cells by Two Different Pathways, and Infection Requires the Activation of the Cellular Kinase ROCK1
FRAMPTON, Arthur R, STOLZ, Donna B, UCHIDA, Hiroaki, GOINS, William F, COHEN, Justus B, GLORIOSO, Joseph C
Published in Journal of Virology (01.10.2007)
Published in Journal of Virology (01.10.2007)
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Journal Article
Generation of Herpesvirus Entry Mediator (HVEM)-Restricted Herpes Simplex Virus Type 1 Mutant Viruses: Resistance of HVEM-Expressing Cells and Identification of Mutations That Rescue Nectin-1 Recognition
UCHIDA, Hiroaki, SHAH, Waris A, OZUER, Ali, FRAMPTON, Arthur R, GOINS, William F, GRANDI, Paola, COHEN, Justus B, GLORIOSO, Joseph C
Published in Journal of Virology (01.04.2009)
Published in Journal of Virology (01.04.2009)
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Deletion of the Virion Host Shut-off Gene Enhances Neuronal-Selective Transgene Expression from an HSV Vector Lacking Functional IE Genes
Miyagawa, Yoshitaka, Verlengia, Gianluca, Reinhart, Bonnie, Han, Fang, Uchida, Hiroaki, Zucchini, Silvia, Goins, William F, Simonato, Michele, Cohen, Justus B, Glorioso, Joseph C
Published in Molecular therapy. Methods & clinical development (15.09.2017)
Published in Molecular therapy. Methods & clinical development (15.09.2017)
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Journal Article
HSV Delivery of a Ligand-regulated Endogenous Ion Channel Gene to Sensory Neurons Results in Pain Control Following Channel Activation
Goss, James R, Cascio, Michael, Goins, William F, Huang, Shaohua, Krisky, David M, Clarke, Richard J, Johnson, Jon W, Yokoyama, Hitoshi, Yoshimura, Naoki, Gold, Michael S, Glorioso, Joseph C
Published in Molecular therapy (01.03.2011)
Published in Molecular therapy (01.03.2011)
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Journal Article
An HSV-based library screen identifies PP1α as a negative TRPV1 regulator with analgesic activity in models of pain
Reinhart, Bonnie, Goins, William F, Harel, Asaff, Chaudhry, Suchita, Goss, James R, Yoshimura, Naoki, de Groat, William C, Cohen, Justus B, Glorioso, Joseph C
Published in Molecular therapy. Methods & clinical development (01.01.2016)
Published in Molecular therapy. Methods & clinical development (01.01.2016)
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Journal Article
Soluble V Domain of Nectin-1/HveC Enables Entry of Herpes Simplex Virus Type 1 (HSV-1) into HSV-Resistant Cells by Binding to Viral Glycoprotein D
KWON, Heechung, QING BAI, BAEK, Hyun-Jung, FELMET, Kelly, BURTON, Edward A, GOINS, William F, COHEN, Justus B, GLORIOSO, Joseph C
Published in Journal of Virology (01.01.2006)
Published in Journal of Virology (01.01.2006)
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Journal Article
Engineering HSV-1 Vectors for Gene Therapy
Goins, William F, Huang, Shaohua, Hall, Bonnie, Marzulli, Marco, Cohen, Justus B, Glorioso, Joseph C
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2020)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2020)
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Engineering HSV-1 vectors for gene therapy
Goins, William F, Huang, Shaohua, Cohen, Justus B, Glorioso, Joseph C
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2014)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2014)
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Glioblastoma infiltration of both tumor- and virus-antigen specific cytotoxic T cells correlates with experimental virotherapy responses
Alayo, Quazim A., Ito, Hirotaka, Passaro, Carmela, Zdioruk, Mykola, Mahmoud, Ahmad Bakur, Grauwet, Korneel, Zhang, Xiaoli, Lawler, Sean E., Reardon, David A., Goins, William F., Fernandez, Soledad, Chiocca, E. Antonio, Nakashima, Hiroshi
Published in Scientific reports (20.03.2020)
Published in Scientific reports (20.03.2020)
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Journal Article
Herpes Simplex Virus Targeting to the EGF Receptor by a gD-Specific Soluble Bridging Molecule
Nakano, Kenji, Asano, Ryutaro, Tsumoto, Kouhei, Kwon, Heechung, Goins, William F, Kumagai, Izumi, Cohen, Justus B, Glorioso, Joseph C
Published in Molecular therapy (01.04.2005)
Published in Molecular therapy (01.04.2005)
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