Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease
Hertel, Johannes, Harms, Amy C., Heinken, Almut, Baldini, Federico, Thinnes, Cyrille C., Glaab, Enrico, Vasco, Daniel A., Pietzner, Maik, Stewart, Isobel D., Wareham, Nicholas J., Langenberg, Claudia, Trenkwalder, Claudia, Krüger, Rejko, Hankemeier, Thomas, Fleming, Ronan M.T., Mollenhauer, Brit, Thiele, Ines
Published in Cell reports (Cambridge) (12.11.2019)
Published in Cell reports (Cambridge) (12.11.2019)
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Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives
Huang, Bei, Chau, Steven W. H., Liu, Yaping, Chan, Joey W. Y., Wang, Jing, Ma, Suk Ling, Zhang, Jihui, Chan, Paul K. S., Yeoh, Yun Kit, Chen, Zigui, Zhou, Li, Wong, Sunny Hei, Mok, Vincent C. T., To, Ka Fai, Lai, Hei Ming, Ng, Simon, Trenkwalder, Claudia, Chan, Francis K. L., Wing, Yun Kwok
Published in Nature communications (02.05.2023)
Published in Nature communications (02.05.2023)
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A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol
Gerdes, Christoph, Waal, Natalia, Offner, Thomas, Fornasiero, Eugenio F., Wender, Nora, Verbarg, Hannes, Manzini, Ivan, Trenkwalder, Claudia, Mollenhauer, Brit, Strohäker, Timo, Zweckstetter, Markus, Becker, Stefan, Rizzoli, Silvio O., Basmanav, Fitnat Buket, Opazo, Felipe
Published in Nature communications (01.06.2020)
Published in Nature communications (01.06.2020)
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Plasma proteomics identify biomarkers predicting Parkinson’s disease up to 7 years before symptom onset
Hällqvist, Jenny, Bartl, Michael, Dakna, Mohammed, Schade, Sebastian, Garagnani, Paolo, Bacalini, Maria-Giulia, Pirazzini, Chiara, Bhatia, Kailash, Schreglmann, Sebastian, Xylaki, Mary, Weber, Sandrina, Ernst, Marielle, Muntean, Maria-Lucia, Sixel-Döring, Friederike, Franceschi, Claudio, Doykov, Ivan, Śpiewak, Justyna, Vinette, Héloїse, Trenkwalder, Claudia, Heywood, Wendy E., Mills, Kevin, Mollenhauer, Brit
Published in Nature communications (18.06.2024)
Published in Nature communications (18.06.2024)
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Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions
Illig, Thomas, Holsboer, Florian, Stiasny-Kolster, Karin, Xiong, Lan, Trenkwalder, Claudia, Eckstein, Gertrud, Montplaisir, Jacques, Wichmann, H-Erich, Schormair, Barbara, Gieger, Christian, Meitinger, Thomas, Oertel, Wolfgang, Lichtner, Peter, Pütz, Benno, Paulus, Walter, Turecki, Gustavo, Jalilzadeh, Shapour, Bachmann, Cornelius G, Peglau, Ines, Winkelmann, Juliane, Müller-Myhsok, Bertram, Fulda, Stephany, Ripke, Stephan, Zimprich, Alexander, Hauk, Stephanie, Rouleau, Guy, Eisensehr, Ilonka
Published in Nature genetics (01.08.2007)
Published in Nature genetics (01.08.2007)
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Niemann-Pick C disease gene mutations and age-related neurodegenerative disorders
Zech, Michael, Nübling, Georg, Castrop, Florian, Jochim, Angela, Schulte, Eva C, Mollenhauer, Brit, Lichtner, Peter, Peters, Annette, Gieger, Christian, Marquardt, Thorsten, Vanier, Marie T, Latour, Philippe, Klünemann, Hans, Trenkwalder, Claudia, Diehl-Schmid, Janine, Perneczky, Robert, Meitinger, Thomas, Oexle, Konrad, Haslinger, Bernhard, Lorenzl, Stefan, Winkelmann, Juliane
Published in PloS one (30.12.2013)
Published in PloS one (30.12.2013)
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Validity and Prognostic Value of a Polygenic Risk Score for Parkinson's Disease
Koch, Sebastian, Laabs, Björn-Hergen, Kasten, Meike, Vollstedt, Eva-Juliane, Becktepe, Jos, Brüggemann, Norbert, Franke, Andre, Krämer, Ulrike M, Kuhlenbäumer, Gregor, Lieb, Wolfgang, Mollenhauer, Brit, Neis, Miriam, Trenkwalder, Claudia, Schäffer, Eva, Usnich, Tatiana, Wittig, Michael, Klein, Christine, König, Inke R, Lohmann, Katja, Krawczak, Michael, Caliebe, Amke
Published in Genes (23.11.2021)
Published in Genes (23.11.2021)
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Efficient Killing of Murine Pluripotent Stem Cells by Natural Killer (NK) Cells Requires Activation by Cytokines and Partly Depends on the Activating NK Receptor NKG2D
Gröschel, Carina, Hübscher, Daniela, Nolte, Jessica, Monecke, Sebastian, Sasse, André, Elsner, Leslie, Paulus, Walter, Trenkwalder, Claudia, Polić, Bojan, Mansouri, Ahmed, Guan, Kaomei, Dressel, Ralf
Published in Frontiers in immunology (26.07.2017)
Published in Frontiers in immunology (26.07.2017)
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Behavioral Changes in Unilaterally 6‐Hydroxy‐Dopamine Lesioned Rats After Transplantation of Differentiated Mouse Embryonic Stem Cells Without Morphological Integration
Baier, Paul Christian, Schindehütte, Jan, Thinyane, Keneuoe, Flügge, Gabriele, Fuchs, Eberhard, Mansouri, Ahmed, Paulus, Walter, Gruss, Peter, Trenkwalder, Claudia
Published in Stem cells (Dayton, Ohio) (01.01.2004)
Published in Stem cells (Dayton, Ohio) (01.01.2004)
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Embryonic stem cell-derived neural progenitors as non-tumorigenic source for dopaminergic neurons
Liao, Mei-Chih, Diaconu, Mihaela, Monecke, Sebastian, Collombat, Patrick, Timaeus, Charles, Kuhlmann, Tanja, Paulus, Walter, Trenkwalder, Claudia, Dressel, Ralf, Mansouri, Ahmed
Published in World journal of stem cells (26.04.2014)
Published in World journal of stem cells (26.04.2014)
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A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease
Zimprich, Alexander, Benet-Pagès, Anna, Struhal, Walter, Graf, Elisabeth, Eck, Sebastian H., Offman, Marc N., Haubenberger, Dietrich, Spielberger, Sabine, Schulte, Eva C., Lichtner, Peter, Rossle, Shaila C., Klopp, Norman, Wolf, Elisabeth, Seppi, Klaus, Pirker, Walter, Presslauer, Stefan, Mollenhauer, Brit, Katzenschlager, Regina, Foki, Thomas, Hotzy, Christoph, Reinthaler, Eva, Harutyunyan, Ashot, Kralovics, Robert, Peters, Annette, Zimprich, Fritz, Brücke, Thomas, Poewe, Werner, Auff, Eduard, Trenkwalder, Claudia, Rost, Burkhard, Ransmayr, Gerhard, Winkelmann, Juliane, Meitinger, Thomas, Strom, Tim M.
Published in American journal of human genetics (15.07.2011)
Published in American journal of human genetics (15.07.2011)
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Absence of an Orphan Mitochondrial Protein, C19orf12, Causes a Distinct Clinical Subtype of Neurodegeneration with Brain Iron Accumulation
Hartig, Monika B., Iuso, Arcangela, Haack, Tobias, Kmiec, Tomasz, Jurkiewicz, Elzbieta, Heim, Katharina, Roeber, Sigrun, Tarabin, Victoria, Dusi, Sabrina, Krajewska-Walasek, Malgorzata, Jozwiak, Sergiusz, Hempel, Maja, Winkelmann, Juliane, Elstner, Matthias, Oexle, Konrad, Klopstock, Thomas, Mueller-Felber, Wolfgang, Gasser, Thomas, Trenkwalder, Claudia, Tiranti, Valeria, Kretzschmar, Hans, Schmitz, Gerd, Strom, Tim M., Meitinger, Thomas, Prokisch, Holger
Published in American journal of human genetics (07.10.2011)
Published in American journal of human genetics (07.10.2011)
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One-step nanoscale expansion microscopy reveals individual protein shapes
Shaib, Ali H, Chouaib, Abed Alrahman, Chowdhury, Rajdeep, Altendorf, Jonas, Mihaylov, Daniel, Zhang, Chi, Krah, Donatus, Imani, Vanessa, Spencer, Russell K W, Georgiev, Svilen Veselinov, Mougios, Nikolaos, Monga, Mehar, Reshetniak, Sofiia, Mimoso, Tiago, Chen, Han, Fatehbasharzad, Parisa, Crzan, Dagmar, Saal, Kim-Ann, Alawieh, Mohamad Mahdi, Alawar, Nadia, Eilts, Janna, Kang, Jinyoung, Soleimani, Alireza, Müller, Marcus, Pape, Constantin, Alvarez, Luis, Trenkwalder, Claudia, Mollenhauer, Brit, Outeiro, Tiago F, Köster, Sarah, Preobraschenski, Julia, Becherer, Ute, Moser, Tobias, Boyden, Edward S, Aricescu, A Radu, Sauer, Markus, Opazo, Felipe, Rizzoli, Silvio O
Published in Nature biotechnology (09.10.2024)
Published in Nature biotechnology (09.10.2024)
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PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome
Schormair, Barbara, Kemlink, David, Roeske, Darina, Eckstein, Gertrud, Xiong, Lan, Lichtner, Peter, Ripke, Stephan, Trenkwalder, Claudia, Zimprich, Alexander, Stiasny-Kolster, Karin, Oertel, Wolfgang, Bachmann, Cornelius G, Paulus, Walter, Högl, Birgit, Frauscher, Birgit, Gschliesser, Viola, Poewe, Werner, Peglau, Ines, Vodicka, Pavel, Vávrová, Jana, Sonka, Karel, Nevsimalova, Sona, Montplaisir, Jacques, Turecki, Gustavo, Rouleau, Guy, Gieger, Christian, Illig, Thomas, Wichmann, H-Erich, Holsboer, Florian, Müller-Myhsok, Bertram, Meitinger, Thomas, Winkelmann, Juliane
Published in Nature genetics (01.08.2008)
Published in Nature genetics (01.08.2008)
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Rare variants in β-Amyloid precursor protein (APP) and Parkinson's disease
Schulte, Eva C, Fukumori, Akio, Mollenhauer, Brit, Hor, Hyun, Arzberger, Thomas, Perneczky, Robert, Kurz, Alexander, Diehl-Schmid, Janine, Hüll, Michael, Lichtner, Peter, Eckstein, Gertrud, Zimprich, Alexander, Haubenberger, Dietrich, Pirker, Walter, Brücke, Thomas, Bereznai, Benjamin, Molnar, Maria J, Lorenzo-Betancor, Oswaldo, Pastor, Pau, Peters, Annette, Gieger, Christian, Estivill, Xavier, Meitinger, Thomas, Kretzschmar, Hans A, Trenkwalder, Claudia, Haass, Christian, Winkelmann, Juliane
Published in European journal of human genetics : EJHG (01.10.2015)
Published in European journal of human genetics : EJHG (01.10.2015)
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Targeted Resequencing and Systematic In Vivo Functional Testing Identifies Rare Variants in MEIS1 as Significant Contributors to Restless Legs Syndrome
Schulte, Eva C., Kousi, Maria, Tan, Perciliz L., Tilch, Erik, Knauf, Franziska, Lichtner, Peter, Trenkwalder, Claudia, Högl, Birgit, Frauscher, Birgit, Berger, Klaus, Fietze, Ingo, Hornyak, Magdolna, Oertel, Wolfgang H., Bachmann, Cornelius G., Zimprich, Alexander, Peters, Annette, Gieger, Christian, Meitinger, Thomas, Müller-Myhsok, Bertram, Katsanis, Nicholas, Winkelmann, Juliane
Published in American journal of human genetics (03.07.2014)
Published in American journal of human genetics (03.07.2014)
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Dilution of candidates: the case of iron-related genes in restless legs syndrome
Oexle, Konrad, Schormair, Barbara, Ried, Janina S, Czamara, Darina, Heim, Katharina, Frauscher, Birgit, Högl, Birgit, Trenkwalder, Claudia, Martin Fiedler, G, Thiery, Joachim, Lichtner, Peter, Prokisch, Holger, Specht, Michael, Müller-Myhsok, Bertram, Döring, Angela, Gieger, Christian, Peters, Annette, Wichmann, H-Erich, Meitinger, Thomas, Winkelmann, Juliane
Published in European journal of human genetics : EJHG (01.04.2013)
Published in European journal of human genetics : EJHG (01.04.2013)
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The PARK8 Locus in Autosomal Dominant Parkinsonism: Confirmation of Linkage and Further Delineation of the Disease-Containing Interval
Zimprich, Alexander, Müller-Myhsok, Bertram, Farrer, Matthew, Leitner, Petra, Sharma, Manu, Hulihan, Mary, Lockhart, Paul, Strongosky, Audrey, Kachergus, Jennifer, Calne, Donald B., Stoessl, Jon, Uitti, Ryan J., Pfeiffer, Ronald F., Trenkwalder, Claudia, Homann, Nikolaus, Ott, Erwin, Wenzel, Karoline, Asmus, Friedrich, Hardy, John, Wszolek, Zbigniew, Gasser, Thomas
Published in American journal of human genetics (01.01.2004)
Published in American journal of human genetics (01.01.2004)
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Journal Article
Rare variants in [beta]-Amyloid precursor protein (APP) and Parkinson's disease
Schulte, Eva C, Fukumori, Akio, Mollenhauer, Brit, Hor, Hyun, Arzberger, Thomas, Perneczky, Robert, Kurz, Alexander, Diehl-schmid, Janine, Hüll, Michael, Lichtner, Peter, Eckstein, Gertrud, Zimprich, Alexander, Haubenberger, Dietrich, Pirker, Walter, Brücke, Thomas, Bereznai, Benjamin, Molnar, Maria J, Lorenzo-betancor, Oswaldo, Pastor, Pau, Peters, Annette, Gieger, Christian, Estivill, Xavier, Meitinger, Thomas, Kretzschmar, Hans A, Trenkwalder, Claudia, Haass, Christian, Winkelmann, Juliane
Published in European journal of human genetics : EJHG (01.10.2015)
Published in European journal of human genetics : EJHG (01.10.2015)
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Correction: Genome-Wide Association Study Identifies Novel Restless Legs Syndrome Susceptibility Loci on 2p14 and 16q12.1
Juliane Winkelmann, Darina Czamara, Barbara Schormair, Franziska Knauf, Eva C. Schulte, Claudia Trenkwalder, Yves Dauvilliers, Olli Polo, Birgit Högl, Klaus Berger, Andrea Fuhs, Nadine Gross, Karin Stiasny-Kolster, Wolfgang Oertel, Cornelius G. Bachmann, Walter Paulus, Lan Xiong, Jacques Montplaisir, Guy A. Rouleau, Ingo Fietze, Jana Vávrová, David Kemlink, Karel Sonka, Sona Nevsimalova, Siong-Chi Lin, Zbigniew Wszolek, Carles Vilariño-Güell, Matthew J. Farrer, Viola Gschliesser, Birgit Frauscher, Tina Falkenstetter, Werner Poewe, Richard P. Allen, Christopher J. Earley, William G. Ondo, Wei-Dong Le, Derek Spieler, Maria Kaffe, Alexander Zimprich, Johannes Kettunen, Markus Perola, Kaisa Silander, Isabelle Cournu-Rebeix, Marcella Francavilla, Claire Fontenille, Bertrand Fontaine, Pavel Vodicka, Holger Prokisch, Peter Lichtner, Paul Peppard, Juliette Faraco, Emmanuel Mignot, Christian Gieger, Thomas Illig, H.-Erich Wichmann, Bertram Müller-Myhsok, Thomas Meitinger
Published in PLoS genetics (01.08.2011)
Published in PLoS genetics (01.08.2011)
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