Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity
Syed, Aleem, Filandr, Frantisek, Patterson-Fortin, Jeffrey, Bacolla, Albino, Ravindranathan, Ramya, Zhou, Jia, McDonald, Drew T, Albuhluli, Mohammed E, Verway-Cohen, Amy, Newman, Joseph A, Tsai, Miaw-Sheue, Jones, Darin E, Schriemer, David C, D’Andrea, Alan D, Tainer, John A
Published in Nucleic acids research (13.10.2023)
Published in Nucleic acids research (13.10.2023)
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Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets
Franco, Francisco M., Jones, Darin E., Harris, Peter K.W., Han, Zhenfu, Wildman, Scott A., Jarvis, Cassie M., Janetka, James W.
Published in Bioorganic & medicinal chemistry (15.05.2015)
Published in Bioorganic & medicinal chemistry (15.05.2015)
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Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation
Arhancet, Graciela B., Walker, Daniel P., Metz, Sue, Fobian, Yvette M., Heasley, Steven E., Carter, Jeffrey S., Springer, John R., Jones, Darin E., Hayes, Michael J., Shaffer, Alexander F., Jerome, Gina M., Baratta, Michael T., Zweifel, Ben, Moore, William M., Masferrer, Jaime L., Vazquez, Michael L.
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
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Chemical screening by time-resolved X-ray scattering to discover allosteric probes
Brosey, Chris A., Link, Todd M., Shen, Runze, Moiani, Davide, Burnett, Kathryn, Hura, Greg L., Jones, Darin E., Tainer, John A.
Published in Nature chemical biology (01.09.2024)
Published in Nature chemical biology (01.09.2024)
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Applying HT-SAXS to chemical ligand screening
Brosey, Chris A, Shen, Runze, Moiani, Davide, Jones, Darin E, Burnett, Kathryn, Hura, Greg L, Tainer, John A
Published in Methods in enzymology (01.01.2023)
Published in Methods in enzymology (01.01.2023)
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An efficient chemical screening method for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2
Moiani, Davide, Link, Todd M, Brosey, Chris A, Katsonis, Panagiotis, Lichtarge, Olivier, Kim, Youngchang, Joachimiak, Andrzej, Ma, Zhijun, Kim, In-Kwon, Ahmed, Zamal, Jones, Darin E, Tsutakawa, Susan E, Tainer, John A
Published in Methods in enzymology (2021)
Published in Methods in enzymology (2021)
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Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor
Howes, Timothy R.L., Sallmyr, Annahita, Brooks, Rhys, Greco, George E., Jones, Darin E., Matsumoto, Yoshihiro, Tomkinson, Alan E.
Published in DNA repair (01.12.2017)
Published in DNA repair (01.12.2017)
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Erratum to “Structure-activity relationships among DNA ligase inhibitors; characterization of a selective uncompetitive DNA ligase I inhibitor” [DNA Repair 60C (2017) 29–39]
Howes, Timothy R.L., Sallmyr, Annahita, Brooks, Rhys, Greco, George E., Jones, Darin E., Matsumoto, Yoshihiro, Tomkinson, Alan E.
Published in DNA repair (01.01.2018)
Published in DNA repair (01.01.2018)
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Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex
South, Michael S., Case, Brenda L., Wood, Rhonda S., Jones, Darin E., Hayes, Michael J., Girard, Thomas J., Lachance, Rhonda M., Nicholson, Nancy S., Clare, Michael, Stevens, Anna M., Stegeman, Roderick A., Stallings, William C., Kurumbail, Ravi G., Parlow, John J.
Published in Bioorganic & medicinal chemistry letters (21.07.2003)
Published in Bioorganic & medicinal chemistry letters (21.07.2003)
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Cloning, sequence, and expression of a blood group B active recombinant alpha-D-galactosidase from pinto bean (Phaseolus vulgaris)
Davis, M.O, Hata, D.J, Johnson, S.A, Jones, D.E, Harmata, M.A, Evans, M.L, Walker, J.C, Smith, D.S
Published in Biochemistry and molecular biology international (01.07.1997)
Published in Biochemistry and molecular biology international (01.07.1997)
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