RyR2 disease mutations at the C-terminal domain intersubunit interface alter closed-state stability and channel activation
Guo, Wenting, Wei, Jinhong, Estillore, John Paul, Zhang, Lin, Wang, Ruiwu, Sun, Bo, Chen, S. R. Wayne
Published in The Journal of biological chemistry (01.07.2021)
Published in The Journal of biological chemistry (01.07.2021)
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Ligand sensitivity of type-1 inositol 1,4,5-trisphosphate receptor is enhanced by the D2594K mutation
Tambeaux, Allison, Aguilar-Sánchez, Yuriana, Santiago, Demetrio J., Mascitti, Madeleine, DiNovo, Karyn M., Mejía-Alvarez, Rafael, Fill, Michael, Wayne Chen, S. R., Ramos-Franco, Josefina
Published in Pflügers Archiv (01.05.2023)
Published in Pflügers Archiv (01.05.2023)
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Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca2+ release
Tian, Xixi, Tang, Yijun, Liu, Yingjie, Wang, Ruiwu, Chen, S R Wayne
Published in Biochemical journal (01.11.2013)
Published in Biochemical journal (01.11.2013)
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Red fluorescent genetically encoded Ca2+ indicators for use in mitochondria and endoplasmic reticulum
Wu, Jiahui, Prole, David L, Shen, Yi, Lin, Zhihong, Gnanasekaran, Aswini, Liu, Yingjie, Chen, Lidong, Zhou, Hang, Chen, S R Wayne, Usachev, Yuriy M, Taylor, Colin W, Campbell, Robert E
Published in Biochemical journal (15.11.2014)
Published in Biochemical journal (15.11.2014)
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Reduced expression of cardiac ryanodine receptor protects against stress-induced ventricular tachyarrhythmia, but increases the susceptibility to cardiac alternans
Zhong, Xiaowei, Vallmitjana, Alexander, Sun, Bo, Xiao, Zhichao, Guo, Wenting, Wei, Jinhong, Ni, Mingke, Chen, Yongxiang, O'Brien, Edward R, Gillis, Anne M, Hoshijima, Masahiko, Takeshima, Hiroshi, Hove-Madsen, Leif, Benitez, Raul, Belke, Darrell, Wayne Chen, S R
Published in Biochemical journal (15.01.2018)
Published in Biochemical journal (15.01.2018)
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Endoplasmic reticulum Ca2+ measurements reveal that the cardiac ryanodine receptor mutations linked to cardiac arrhythmia and sudden death alter the threshold for store-overload-induced Ca2+ release
Jones, Peter P, Jiang, Dawei, Bolstad, Jeff, Hunt, Donald J, Zhang, Lin, Demaurex, Nicolas, Chen, S R Wayne
Published in Biochemical journal (15.05.2008)
Published in Biochemical journal (15.05.2008)
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Removal of FKBP12.6 Does Not Alter the Conductance and Activation of the Cardiac Ryanodine Receptor or the Susceptibility to Stress-induced Ventricular Arrhythmias
Xiao, Jianmin, Tian, Xixi, Jones, Peter P., Bolstad, Jeff, Kong, Huihui, Wang, Ruiwu, Zhang, Lin, Duff, Henry J., Gillis, Anne M., Fleischer, Sidney, Kotlikoff, Michael, Copello, Julio A., Chen, S. R. Wayne
Published in The Journal of biological chemistry (30.11.2007)
Published in The Journal of biological chemistry (30.11.2007)
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Enhanced Cytosolic Ca2+ Activation Underlies a Common Defect of Central Domain Cardiac Ryanodine Receptor Mutations Linked to Arrhythmias
Xiao, Zhichao, Guo, Wenting, Sun, Bo, Hunt, Donald J., Wei, Jinhong, Liu, Yingjie, Wang, Yundi, Wang, Ruiwu, Jones, Peter P., Back, Thomas G., Chen, S. R. Wayne
Published in The Journal of biological chemistry (18.11.2016)
Published in The Journal of biological chemistry (18.11.2016)
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Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts
Xiao, Bailong, Zhong, Guofeng, Obayashi, Masakazu, Yang, Dongmei, Chen, Keyun, Walsh, Michael P, Shimoni, Yakhin, Cheng, Heping, Ter Keurs, Henk, Chen, S R Wayne
Published in Biochemical journal (15.05.2006)
Published in Biochemical journal (15.05.2006)
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Localization of the Dantrolene-binding Sequence near the FK506-binding Protein-binding Site in the Three-dimensional Structure of the Ryanodine Receptor
Wang, Ruiwu, Zhong, Xiaowei, Meng, Xing, Koop, Andrea, Tian, Xixi, Jones, Peter P., Fruen, Bradley R., Wagenknecht, Terence, Liu, Zheng, Chen, S.R. Wayne
Published in The Journal of biological chemistry (08.04.2011)
Published in The Journal of biological chemistry (08.04.2011)
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K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 association
Hunt, Donald J, Jones, Peter P, Wang, Ruiwu, Chen, Wenqian, Bolstad, Jeff, Chen, Keyun, Shimoni, Yakhin, Chen, S R Wayne
Published in Biochemical journal (15.06.2007)
Published in Biochemical journal (15.06.2007)
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The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice
Zhang, Jingqun, Chen, Biyi, Zhong, Xiaowei, Mi, Tao, Guo, Ang, Zhou, Qiang, Tan, Zhen, Wu, Guogen, Chen, Alexander W, Fill, Michael, Song, Long-Sheng, Chen, S R Wayne
Published in Biochemical journal (01.07.2014)
Published in Biochemical journal (01.07.2014)
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RyR2 Mutations Linked to Ventricular Tachycardia and Sudden Death Reduce the Threshold for Store-Overload-Induced Ca2+Release (SOICR)
Jiang, Dawei, Xiao, Bailong, Yang, Dongmei, Wang, Ruiwu, Choi, Philip, Zhang, Lin, Cheng, Heping, Chen, R. Wayne, MacLennan, David H.
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2004)
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