Accelerating the discovery of DGAT1 inhibitors through the application of parallel medicinal chemistry (PMC)
Yu, Yang, Wu, Zhicai, Shi, Zhi-Cai, He, Shuwen, Lai, Zhong, Cernak, Timothy A., Vachal, Petr, Liu, Min, Liu, Jian, Hong, Qingmei, Jian, Tianying, Guiadeen, Deodial, Krikorian, Arto, Sperbeck, Donald M., Verras, Andreas, Sonatore, Lisa M., Murphy, Beth A., Wiltsie, Judyann, Chung, Christine C., Gorski, Judith N., Liu, Jinqi, Xiao, Jianying, Wolff, Michael, Tong, Sharon X., Madeira, Maria, Karanam, Bindhu V., Shen, Dong-Ming, Balkovec, James M., De Vita, Robert J., Pinto, Shirly, Nargund, Ravi P.
Published in Bioorganic & medicinal chemistry letters (01.06.2019)
Published in Bioorganic & medicinal chemistry letters (01.06.2019)
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Benzimidazole-based DGAT1 inhibitors with a [3.1.0] bicyclohexane carboxylic acid moiety
He, Shuwen, Lai, Zhong, Hong, Qingmei, Shang, Jackie, Reibarkh, Mikhail, Kuethe, Jeffrey T., Liu, Jian, Guiadeen, Deodial, Krikorian, Arto D., Cernak, Timothy A., Dykstra, Kevin D., Sperbeck, Donald M., Wu, Zhicai, Yu, Yang, Yang, Ginger X., Jian, Tianying, Verras, Andreas, Sonatore, Lisa M., Wiltsie, Judyann, Chung, Christine C., Murphy, Beth A., Gorski, Judith N., Liu, Jinqi, Xiao, Jianying, Wolff, Michael, Tong, Sharon X., Madeira, Maria, Karanam, Bindhu V., Shen, Dong-Ming, Balkovec, James M., Pinto, Shirly, Nargund, Ravi P., DeVita, Robert J.
Published in Bioorganic & medicinal chemistry letters (15.05.2019)
Published in Bioorganic & medicinal chemistry letters (15.05.2019)
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A novel benzazepinone sodium channel blocker with oral efficacy in a rat model of neuropathic pain
Hoyt, Scott B., London, Clare, Abbadie, Catherine, Felix, John P., Garcia, Maria L., Jochnowitz, Nina, Karanam, Bindhu V., Li, Xiaohua, Lyons, Kathryn A., McGowan, Erin, Priest, Birgit T., Smith, McHardy M., Warren, Vivien A., Thomas-Fowlkes, Brande S., Kaczorowski, Gregory J., Duffy, Joseph L.
Published in Bioorganic & medicinal chemistry letters (15.06.2013)
Published in Bioorganic & medicinal chemistry letters (15.06.2013)
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Benzazepinone Nav1.7 blockers : Potential treatments for neuropathic pain
HOYT, Scott B, LONDON, Clare, KARANAM, Bindhu V, XIAOHUA LI, LYONS, Kathryn A, MCGOWAN, Erin, EUAN MACINTYRE, D, MARTIN, William J, PRIEST, Birgit T, SMITH, Mchardy M, TSCHIRRET-GUTH, Richard, WARREN, Vivien A, OK, Hyun, WILLIAMS, Brande S, KACZOROWSKI, Gregory J, PARSONS, William H, GONZALEZ, Edward, DUFFY, Joseph L, ABBADIE, Catherine, DEAN, Brian, FELIX, John P, GARCIA, Maria L, JOCHNOWITZ, Nina
Published in Bioorganic & medicinal chemistry letters (15.11.2007)
Published in Bioorganic & medicinal chemistry letters (15.11.2007)
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Imidazopyridines : A novel class of hNav1.7 channel blockers
LONDON, Clare, HOYT, Scott B, LYONS, Kathryn A, XIAOHUA LI, KARANAM, Bindhu V, JOCHNOWITZ, Nina, GARCIA, Maria L, FELIX, John P, DEAN, Brian, ABBADIE, Catherine, KACZOROWSKI, Gregory J, DUFFY, Joseph L, PARSONS, William H, WILLIAMS, Brande S, WARREN, Vivien A, TSCHIRRET-GUTH, Richard, SMITH, Mchardy M, PRIEST, Birgit T, MCGOWAN, Erin, MARTIN, William J
Published in Bioorganic & medicinal chemistry letters (01.03.2008)
Published in Bioorganic & medicinal chemistry letters (01.03.2008)
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Discovery of imidazole carboxamides as potent and selective CCK1R agonists
Zhu, Cheng, Hansen, Alexa R., Bateman, Thomas, Chen, Zhesheng, Holt, Tom G., Hubert, James A., Karanam, Bindhu V., Lee, Susan J., Pan, Jie, Qian, Su, Reddy, Vijay B.G., Reitman, Marc L., Strack, Alison M., Tong, Vincent, Weingarth, Drew T., Wolff, Michael S., MacNeil, Doug J., Weber, Ann E., Duffy, Joseph L., Edmondson, Scott D.
Published in Bioorganic & medicinal chemistry (01.08.2008)
Published in Bioorganic & medicinal chemistry (01.08.2008)
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Orally bioavailable, indole-based nonpeptide GnRH receptor antagonists with high potency and functional activity
Ashton, Wallace T., Sisco, Rosemary M., Kieczykowski, Gerard R., Yang, Yi Tien, Yudkovitz, Joel B., Cui, Jisong, Mount, George R., Ren, Rena Ning, Wu, Tsuei-Ju, Shen, Xiaolan, Lyons, Kathryn A., Mao, An-Hua, Carlin, Josephine R., Karanam, Bindhu V., Vincent, Stella H., Cheng, Kang, Goulet, Mark T.
Published in Bioorganic & medicinal chemistry letters (08.10.2001)
Published in Bioorganic & medicinal chemistry letters (08.10.2001)
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2-Arylindoles as gonadotropin releasing hormone (GnRH) antagonists: optimization of the tryptamine side chain
Young, Jonathan R., Huang, Song X., Walsh, Thomas F., Wyvratt, Matthew J., Yang, Yi Tien, Yudkovitz, Joel B., Cui, Jisong, Mount, George R., Ren, Rena Ning, Wu, Tsuei-Ju, Shen, Xiaolan, Lyons, Kathryn A., Mao, An-Hua, Carlin, Josephine R., Karanam, Bindhu V., Vincent, Stella H., Cheng, Kang, Goulet, Mark T.
Published in Bioorganic & medicinal chemistry letters (11.03.2002)
Published in Bioorganic & medicinal chemistry letters (11.03.2002)
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A Novel Synthesis of Malic Acid Capped Silver Nanoparticles using Solanum lycopersicums Fruit Extract
Umadevi, M., Bindhu, M.R., Sathe, V.
Published in Journal of materials science & technology (01.04.2013)
Published in Journal of materials science & technology (01.04.2013)
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In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: Identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism
Vincent, Styliani H., Karanam, Bindhu V., Painter, Susan K., Chiu, Shuet-Hing L.
Published in Archives of biochemistry and biophysics (01.05.1992)
Published in Archives of biochemistry and biophysics (01.05.1992)
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Journal Article
Imidazopyridines: A novel class of hNav1.7 channel blockers
London, Clare, Hoyt, Scott B., Parsons, William H., Williams, Brande S., Warren, Vivien A., Tschirret-Guth, Richard, Smith, McHardy M., Priest, Birgit T., McGowan, Erin, Martin, William J., Lyons, Kathryn A., Li, Xiaohua, Karanam, Bindhu V., Jochnowitz, Nina, Garcia, Maria L., Felix, John P., Dean, Brian, Abbadie, Catherine, Kaczorowski, Gregory J., Duffy, Joseph L.
Published in Bioorganic & medicinal chemistry letters (01.03.2008)
Published in Bioorganic & medicinal chemistry letters (01.03.2008)
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Dynamics of laser produced silver plasma under film deposition conditions studied using optical emission spectroscopy
Issac, Riju C., Vasudevan Pillai, K., Harilal, S.S., Varier, Geetha K., Bindhu, C.V., Gopinath, Pramod, Radhakrishnan, P., Nampoori, V.P.N., Vallabhan, C.P.G.
Published in Applied surface science (01.02.1998)
Published in Applied surface science (01.02.1998)
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Thermal lens technique to study the effect of pH on electronic energy transfer in organic dye mixtures
Kurian, Achamma, George, Sajan D., Bindhu, C.V., Nampoori, V.P.N., Vallabhan, C.P.G.
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (01.07.2007)
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (01.07.2007)
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Investigations on nanosecond laser produced plasma in air from the multi-component material YBa2Cu3O7
VARIER, G. K, ISSAC, R. C, HARILAL, S. S, BINDHU, C. V, NAMPOORI, V. P. N, VALLABHAN, C. P. G
Published in Spectrochimica acta. Part B: Atomic spectroscopy (01.05.1997)
Published in Spectrochimica acta. Part B: Atomic spectroscopy (01.05.1997)
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Anomalous profile of a self-reversed resonance line from Ba+ in a laser produced plasma from YBa2Cu3O7
ISSAC, R. C, HARILAL, S. S, BINDHU, C. V, VARIER, G. K, NAMPOORI, V. P. N, VALLABHAN, C. P. G
Published in Spectrochimica acta. Part B: Atomic spectroscopy (10.10.1997)
Published in Spectrochimica acta. Part B: Atomic spectroscopy (10.10.1997)
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