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Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair
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Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins
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A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes
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CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits
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Disease modeling by efficient genome editing using a near PAM-less base editor in vivo
Rosello, Marion, Serafini, Malo, Mignani, Luca, Finazzi, Dario, Giovannangeli, Carine, Mione, Marina C., Concordet, Jean-Paul, Del Bene, Filippo
Published in Nature communications (15.06.2022)
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High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion
Momose, Tsuyoshi, De Cian, Anne, Shiba, Kogiku, Inaba, Kazuo, Giovannangeli, Carine, Concordet, Jean-Paul
Published in Scientific reports (06.08.2018)
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Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression
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Published in Nature communications (04.11.2022)
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Sox2, Tlx, Gli3, and Her9 converge on Rx2 to define retinal stem cells in vivo
Reinhardt, Robert, Centanin, Lázaro, Tavhelidse, Tinatini, Inoue, Daigo, Wittbrodt, Beate, Concordet, Jean-Paul, Martinez-Morales, Juan Ramón, Wittbrodt, Joachim
Published in The EMBO journal (03.06.2015)
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Characterization of dystrophin deficient rats: a new model for Duchenne muscular dystrophy
Larcher, Thibaut, Lafoux, Aude, Tesson, Laurent, Remy, Séverine, Thepenier, Virginie, François, Virginie, Le Guiner, Caroline, Goubin, Helicia, Dutilleul, Maéva, Guigand, Lydie, Toumaniantz, Gilles, De Cian, Anne, Boix, Charlotte, Renaud, Jean-Baptiste, Cherel, Yan, Giovannangeli, Carine, Concordet, Jean-Paul, Anegon, Ignacio, Huchet, Corinne
Published in PloS one (13.10.2014)
Published in PloS one (13.10.2014)
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Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells
Garcin, Edwige B, Gon, Stéphanie, Sullivan, Meghan R, Brunette, Gregory J, Cian, Anne De, Concordet, Jean-Paul, Giovannangeli, Carine, Dirks, Wilhelm G, Eberth, Sonja, Bernstein, Kara A, Prakash, Rohit, Jasin, Maria, Modesti, Mauro
Published in PLoS genetics (04.10.2019)
Published in PLoS genetics (04.10.2019)
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2C-Cas9: a versatile tool for clonal analysis of gene function
Di Donato, Vincenzo, De Santis, Flavia, Auer, Thomas O, Testa, Noé, Sánchez-Iranzo, Héctor, Mercader, Nadia, Concordet, Jean-Paul, Del Bene, Filippo
Published in Genome research (01.05.2016)
Published in Genome research (01.05.2016)
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Cancer translocations in human cells induced by zinc finger and TALE nucleases
Piganeau, Marion, Ghezraoui, Hind, De Cian, Anne, Guittat, Lionel, Tomishima, Mark, Perrouault, Loic, René, Oliver, Katibah, George E, Zhang, Lei, Holmes, Michael C, Doyon, Yannick, Concordet, Jean-Paul, Giovannangeli, Carine, Jasin, Maria, Brunet, Erika
Published in Genome research (01.07.2013)
Published in Genome research (01.07.2013)
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Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression
Sandoz, Jérémy, Nagy, Zita, Catez, Philippe, Caliskan, Gizem, Geny, Sylvain, Renaud, Jean-Baptiste, Concordet, Jean-Paul, Poterszman, Arnaud, Tora, Laszlo, Egly, Jean-Marc, Le May, Nicolas, Coin, Frédéric
Published in Nature communications (20.03.2019)
Published in Nature communications (20.03.2019)
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Cooperation, cis-interactions, versatility and evolutionary plasticity of multiple cis-acting elements underlie krox20 hindbrain regulation
Torbey, Patrick, Thierion, Elodie, Collombet, Samuel, de Cian, Anne, Desmarquet-Trin-Dinh, Carole, Dura, Mathilde, Concordet, Jean-Paul, Charnay, Patrick, Gilardi-Hebenstreit, Pascale
Published in PLoS genetics (06.08.2018)
Published in PLoS genetics (06.08.2018)
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