Molecular Evolution of Aromatic Polyketides and Comparative Sequence Analysis of Polyketide Ketosynthase and 16S Ribosomal DNA Genes from Various Streptomyces Species
Metsä-Ketelä, Mikko, Halo, Laura, Munukka, Eveliina, Hakala, Juha, Mäntsälä, Pekka, Ylihonko, Kristiina
Published in Applied and Environmental Microbiology (01.09.2002)
Published in Applied and Environmental Microbiology (01.09.2002)
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Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster
Räty, Kaj, Kantola, Jaana, Hautala, Anne, Hakala, Juha, Ylihonko, Kristiina, Mäntsälä, Pekka
Published in Gene (26.06.2002)
Published in Gene (26.06.2002)
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Studies on a Second and Third Ring Cyclization in Anthracycline Biosynthesis
HAUTALA, ANNE, TORKKELL, SIRKE, RÄTY, KAJ, KUNNARI, TERO, KANTOLA, JAANA, MÄNTSÄLÄ, PEKKA, HAKALA, JUHA, YLIHONKO, KRISTIINA
Published in Journal of antibiotics (01.02.2003)
Published in Journal of antibiotics (01.02.2003)
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Isolation and characterization of 8-demethoxy steffimycins and generation of 2,8-demethoxy steffimycins in Streptomyces steffisburgensis by the nogalamycin biosynthesis genes
Kunnari, T, Tuikkanen, J, Hautala, A, Hakala, J, Ylihonko, K, Mantsala, P
Published in Journal of antibiotics (1997)
Published in Journal of antibiotics (1997)
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An efficient approach for screening minimal PKS genes from Streptomyces
Metsä-Ketelä, Mikko, Salo, Virpi, Halo, Laura, Hautala, Anne, Hakala, Juha, Mäntsälä, Pekka, Ylihonko, Kristiina
Published in FEMS microbiology letters (01.11.1999)
Published in FEMS microbiology letters (01.11.1999)
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Elucidation of anthracyclinone biosynthesis by stepwise cloning of genes for anthracyclines from three different Streptomyces spp
Kantola, Jaana, Kunnari, Tero, Hautala, Anne, Hakala, Juha, Ylihonko, Kristiina, Mantsala, Pekka
Published in Microbiology (Society for General Microbiology) (01.01.2000)
Published in Microbiology (Society for General Microbiology) (01.01.2000)
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Characterization of mutations in aclacinomycin A-non-producing Streptomyces galilaeus strains with altered glycosylation patterns
Raty, Kaj, Hautala, Anne, Torkkell, Sirke, Kantola, Jaana, Mantsala, Pekka, Hakala, Juha, Ylihonko, Kristiina
Published in Microbiology (Society for General Microbiology) (01.11.2002)
Published in Microbiology (Society for General Microbiology) (01.11.2002)
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Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes
Ylihonko, Kristiina, Hakala, Juha, Kunnari, Tero, Mantsalala, Pekka
Published in Microbiology (Society for General Microbiology) (01.08.1996)
Published in Microbiology (Society for General Microbiology) (01.08.1996)
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Hybrid anthracycline antibiotics: production of new anthracyclines by cloned genes from Streptomyces purpurascens in Streptomyces galilaeus
Niemi, Jarmo, Ylihonko, Kristiina, Hakala, Juha, Parssinen, Raimo, Kopio, Anja, Mantsala, Pekka
Published in Microbiology (Society for General Microbiology) (01.06.1994)
Published in Microbiology (Society for General Microbiology) (01.06.1994)
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Modifications of aclacinomycin T by aclacinomycin methyl esterase (RdmC) and aclacinomycin-10-hydroxylase (RdmB) from Streptomyces purpurascens
Wang, Yulong, Niemi, Jarmo, Airas, Kalervo, Ylihonko, Kristiina, Hakala, Juha, Mäntsälä, Pekka
Published in Biochimica et biophysica acta (14.07.2000)
Published in Biochimica et biophysica acta (14.07.2000)
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Characterization of aklavinone-11-hydroxylase from Streptomyces purpurascens
Niemi, Jarmo, Wang, Yulong, Airas, Kalervo, Ylihonko, Kristiina, Hakala, Juha, Mäntsälä, Pekka
Published in Biochimica et biophysica acta (10.02.1999)
Published in Biochimica et biophysica acta (10.02.1999)
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Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline
Kantola, Jaana, Blanco, Gloria, Hautala, Anne, Kunnari, Tero, Hakala, Juha, Mendez, Carmen, Ylihonko, Kristiina, Mäntsälä, Pekka, Salas, Jose
Published in Chemistry & biology (01.10.1997)
Published in Chemistry & biology (01.10.1997)
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